Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Margaret M, Racke"'
Autor:
Braydon L. Burgess, Pamela F. Parkinson, Margaret M. Racke, Veronica Hirsch-Reinshagen, Jianjia Fan, Charmaine Wong, Sophie Stukas, Louise Theroux, Jeniffer Y. Chan, James Donkin, Anna Wilkinson, Danielle Balik, Brian Christie, Judes Poirier, Dieter Lütjohann, Ronald B. DeMattos, Cheryl L. Wellington
Publikováno v:
Journal of Lipid Research, Vol 49, Iss 6, Pp 1254-1267 (2008)
Cholesterol homeostasis is of emerging therapeutic importance for Alzheimer's disease (AD). Agonists of liver-X-receptors (LXRs) stimulate several genes that regulate cholesterol homeostasis, and synthetic LXR agonists decrease neuropathological and
Externí odkaz:
https://doaj.org/article/cdf2eaade54540b79ab0a478dcf20fe2
Autor:
Andreas Ebneth, Astrid Bottelbergs, Cindy Wintmolders, Philippe Goniot, Nathalie Schussler, Emmanuel Brault, Gary J. Nabel, David R. Riddell, Yaming Wang, Alexis Bretteville, Margaret M. Racke, Véronique Blanc, Bart Roucourt, Zhi Yong Yang, Laurent Pradier, Tyler McGathey, Bradford Elmer, Jirong Lu, Michael J. O'Neill, Martine Latta-Mahieu, Liesbeth Mertens, Caroline Hersley, Paul Ferrari, Mati Lopez-Grancha, Pascal Barneoud, Nicolas Moindrot, Philippe Bertrand, Véronique Blanchard, Valerie Roudieres, Ling Liu, Sofie Carmans, Peter Larsen
Publikováno v:
Glia. 66:492-504
Chronic inflammation represents a central component in the pathogenesis of Alzheimer's disease (AD). Recent work suggests that breaking immune tolerance by Programmed cell Death-1 (PD1) checkpoint inhibition produces an IFN-γ-dependent systemic immu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a90df3d92064983926f01868f13e0e3
https://doi.org/10.1002/glia.23260
https://doi.org/10.1002/glia.23260
Autor:
Margaret M. Racke, Linda K. Thompson, David L. McKinzie, David R. Riddell, Zhixiang Yang, Leonard N. Boggs
Publikováno v:
Alzheimer's & Dementia. 14
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ad6b247170928be9bafc173972de631
https://doi.org/10.1016/j.jalz.2018.06.743
https://doi.org/10.1016/j.jalz.2018.06.743
Autor:
John A. Tzaferis, Justin T. Hole, Feng Liu, Margaret M. Racke, Ronald Demattos, Herold Oluoch
Publikováno v:
Alzheimer's & Dementia. 13
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71a87acf1f8341d4d069519af6b5a2ec
https://doi.org/10.1016/j.jalz.2017.06.697
https://doi.org/10.1016/j.jalz.2017.06.697
Autor:
Theresa A. Day, Margaret M. Racke, Jirong Lu, Justin T. Hole, Ronald B. DeMattos, Chi-Kin Chow
Publikováno v:
Alzheimer's & Dementia. 12
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d5aa14ae2d54ee7d3c11380096007ad
https://doi.org/10.1016/j.jalz.2016.06.829
https://doi.org/10.1016/j.jalz.2016.06.829
Autor:
John A. Tzaferis, Zeshan Ahmed, Ying Yt. Yang, Jirong Lu, Ronald B. DeMattos, John R. Sims, Zhixiang Yang, Dustin J. Mergott, Scott A. Monk, Celedon Gonzales, Feng Liu, Michael C. Irizarry, Philip Iversent, Michael Hutton, Patrick C. May, Christer Nordstedt, Wesley H. Anderson, Alice Fisher, Justin T. Hole, Herold Oluoch, Leonard N. Boggs, Margaret M. Racke
Publikováno v:
Alzheimer's & Dementia. 12
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cabaa7afeb5f2ff39a1d02150b35b1ca
https://doi.org/10.1016/j.jalz.2016.07.146
https://doi.org/10.1016/j.jalz.2016.07.146
Autor:
Philip Iversent, Jirong Lu, Theresa A. Day, Wesley H. Anderson, Margaret M. Racke, Alice Fisher, Zhixiang Yang, John A. Tzaferis, Dustin J. Mergott, Scott A. Monk, Leonard N. Boggs, Michael C. Irizarry, Patrick C. May, Zeshan Ahmed, Feng Liu, John R. Sims, Justin T. Hole, Michael Hutton, Ying Y.T. Yang, Ronald B. DeMattos, Christer Nordstedt, Celedon Gonzales
Publikováno v:
Alzheimer's & Dementia. 11
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3af55a735cd66417c6c43c5638258b69
https://doi.org/10.1016/j.jalz.2015.07.364
https://doi.org/10.1016/j.jalz.2015.07.364
Autor:
Donna D. Brown, David M. Holtzman, Laura I. Boone, Matthew T. Bryan, Bruce D. Gitter, Kelly R. Bales, Steven M. Paul, Maia Parsadainian, Wherly P. Hoffman, Daniel K. Ness, Kathy S. Piroozi, William H. Jordan, Deena L. Hepburn, Patrick J. C. May, Margaret M. Racke, Ronald Demattos
Publikováno v:
The Journal of Neuroscience. 25:629-636
Passive immunization with an antibody directed against the N terminus of amyloid beta (Abeta) has recently been reported to exacerbate cerebral amyloid angiopathy (CAA)-related microhemorrhage in a transgenic animal model. Although the mechanism resp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47a1652349fde1da6bc5f907996e583d
https://doi.org/10.1523/jneurosci.4337-04.2005
https://doi.org/10.1523/jneurosci.4337-04.2005
Autor:
Songqing Na, Andrew L. Glasebrook, Neal W. Roehm, Chan Hsin S. Chang, Margaret M. Racke, Marian Mosior, Steve Kovacevic
Publikováno v:
Journal of Neurochemistry. 80:1039-1048
Activated caspase-3 is considered an important enzyme in the cell death pathway. To study the specific role of caspase-3 activation in neuronal cells, we generated a stable tetracycline-regulated SK-N-MC neuroblastoma cell line, which expressed a hig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::261ac4caca38c0aec12d7376188b8cf1
https://doi.org/10.1046/j.0022-3042.2002.00787.x
https://doi.org/10.1046/j.0022-3042.2002.00787.x
Autor:
Ronald B. DeMattos, Patrick C. May, Anni Westerlund, Ulf Andreasson, Henrik Zetterberg, Niklas Mattsson, Maria Olsson, Erik Portelius, Robert A. Dean, Kaj Blennow, Margaret M. Racke
Publikováno v:
Alzheimer's Research & Therapy
The β-secretase enzyme, β-site amyloid precursor protein-cleaving enzyme 1 (BACE1), cleaves amyloid precursor protein (APP) in the first step in β-amyloid (Aβ) peptide production. Thus, BACE1 is a key target for candidate disease-modifying treatm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a3d1637729b859d7e11ebc82eb33ee9
http://europepmc.org/articles/PMC4233234
http://europepmc.org/articles/PMC4233234