Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Margaret L. Tang"'
Autor:
Gady Cojocaru, Margaret L. Tang, Patrick Wall, Sandeep Kumar, Eran Ophir, Hsin-Yuan Cheng, John J. Hunter, Ling Leung, Andrew W. Drake, Maya F. Kotturi, Masha Frenkel, Kathryn Logronio, David Bernados, Moran Galperin, Kyle Hansen, Spencer Liang, Samir Qurashi, Mark A. White, Zoya Alteber, Sarah Whelan
Publikováno v:
Cancer Immunology, Immunotherapy. 70:3525-3540
Immune checkpoint inhibitors (ICIs) have emerged as promising therapies for the treatment of cancer. However, existing ICIs, namely PD-(L)1 and CTLA-4 inhibitors, generate durable responses only in a subset of patients. TIGIT is a co-inhibitory recep
Autor:
Giuseppe A. Papalia, Margaret L. Tang, Mary Haak-Frendscho, Andrew W. Drake, Scott L. Klakamp, Gregory Landes
Publikováno v:
Analytical Biochemistry. 429:58-69
To characterize a proprietary therapeutic monoclonal antibody (mAb) candidate, a rigorous biophysical study consisting of 53 Biacore and kinetic exclusion assay (KinExA) experiments was undertaken on the therapeutic mAb complexing with its target ant