Výsledky vyhledávání - "Margaret L. Harbison"

Mice homozygous for a null mutation of activin βB are viable and fertile

Autor: Margaret L. Harbison, Maureen Gendron-Maguire, Thomas Gridley, Heinrich Schrewe

Publikováno v: Mechanisms of Development. 47:43-51

We have made a null mutation in the mouse activin beta B gene by deleting the portion of the gene encoding the proteolytic cleavage site and the majority of the coding region for the mature processed protein. Mice homozygous for this mutation complet

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::209c0a572fc04f31a62b64ea4f698574
https://doi.org/10.1016/0925-4773(94)90094-9

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Androgenetic mouse embryonic stem cells are pluripotent and cause skeletal defects in chimeras: Implications for genetic imprinting

Autor: Susan J. Abbondanzo, Margaret L. Harbison, Colin L. Stewart, Jeffrey R. Mann, Inder Gadi

Publikováno v: Cell. 62:251-260

The inviability of diploid androgenetic and parthenogenetic embryos suggests imprinting of paternal and maternal genes during germ cell development, and differential expression of loci depending on parental inheritance appears to be involved. To faci

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea5499a58a4499d0f889cb13f00f25e9
https://doi.org/10.1016/0092-8674(90)90363-j

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Cell proliferation and global methylation status changes in mouse liver after phenobarbital and/or choline-devoid, methionine-deficient diet administration

Autor: Margaret L. Harbison, J C Downing, Jay I. Goodman, Jennifer L. Counts, Juan I. Sarmiento, R. Michael McClain

Publikováno v: Carcinogenesis. 17(6)

Our laboratory is testing the hypothesis that hypomethylation of DNA [a decreased content of 5-methylcytosine (5MeC) compared with cytosine] facilitates aberrant oncogene expression involved in tumorigenesis, using a model system of mouse strains wit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01aa99291b1611e876077e46513563bf
https://pubmed.ncbi.nlm.nih.gov/8681439

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Evaluation of an interleukin-1 receptor antagonist in the rat acetic acid-induced colitis model

Autor: J. Little, D. Schmolze, A. Srivastava, R. C. Thompson, Margaret L. Harbison, P. L. Kilian, C. L. Wilson, R. S. Chesonis, M. Pignatello, Peter C. Will, T. K. Thomas, Julia Symington

Publikováno v: Agents and actions. 34(1-2)

The anti-inflammatory activity of the IL-1 receptor antagonist, IL-1ra, was evaluated in the acetic acid (HOAc)-induced model of colitis in rats. Animals treated with 10 mg/kg IL-1ra or vehicle were evaluated for general health, acute phase response,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a78519d5327243f42a741f6967d2442
https://pubmed.ncbi.nlm.nih.gov/1838896

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Mice homozygous for the ablm1 mutation show poor viability and depletion of selected B and T cell populations

Autor: Elizabeth J. Robertson, Teresa J Humaran, Jeff D. Hardin, Katherine S. Bowdish, Margaret L. Harbison, Alan M. Stall, Stephen P. Goff, Pamela L. Schwartzberg, Sharon Boast

Publikováno v: Cell. 65(7)

The c-abl gene, originally identified as the cellular homolog of the transforming gene of the Abelson murine leukemia virus, encodes a protein-tyrosine kinase of unknown function that is expressed in all mammalian tissues. We have previously describe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2580663765450a0af9a755624475e82
https://pubmed.ncbi.nlm.nih.gov/2065353

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Adjusting for confounded variables: Pulmonary function and smoking in a special population

Autor: Joseph D. Brain, Margaret L. Harbison, Henry A. Feldman

Publikováno v: Environmental Research. 43:251-266

Confounded variables present an obstacle to valid inference in many environmental and occupational studies. We describe a series of procedures that we used to address this problem in a study of pulmonary function and smoking. Subjects were drawn from

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::830eb36b4d5fe465ab11306267262504
https://doi.org/10.1016/s0013-9351(87)80076-2

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Protein characterization and targeted disruption of Grg, a mouse gene related to the groucho transcript of the Drosophila enhancer of split complex

Autor: Maureen Gendron-Maguire, Margaret L. Harbison, Moisés Mallo, Thomas Gridley

Publikováno v: Scopus-Elsevier
CIÊNCIAVITAE

The Grg gene encodes a 197 amino acid protein homologous to the amino-terminal domain of the product of the groucho gene of the Drosophila Enhancer of split complex. Analysis with a polyclonal antisera specific for the Grg protein revealed that Grg i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d571dc6a522b252f419258b2467bb502
http://www.scopus.com/inward/record.url?eid=2-s2.0-0028823991&partnerID=MN8TOARS