Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Margaret Kiddoe"'
Autor:
Margaret Kiddoe, Olivia Linton, C. Edgar Cook, John A. Kepler, Zhihua Sui, Sheela Bhattacharjee, George F. Allan, Scott G. Lundeen, Chunyang Jin, Govindarajan Manikumar
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 17:5754-5757
A series of novel 11β-aryl-4′,5′-dihydrospiro[estra-4,9-diene-17β,4′-oxazole] analogs have been evaluated for their antagonist hormonal properties using the T47D cell-based alkaline phosphatase assay and the A549 cell-based functional assay.
Autor:
Kimberly N. Beers, Stephanie C. Hamel, Carolyn Campen, Steven K. Wetter, Stephen S. Palmer, Peter J. Connolly, Pat Kraft, Donna Haynes-Johnson, Audrey Phillips, Margaret Kiddoe, Muh Tsann Lai
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 7:2551-2556
Research directed toward the discovery of non-steroidal ligands for steroid receptors led to the preparation of a series of substituted 1-phenyl-7-benzyltetrahydroindazole-3-carboxaldehydes. Appropriately substituted 3-formyl analogs (4) were found t
Autor:
C. Edgar Cook, Olivia Linton, George F. Allan, Sheela Bhattacharjee, Scott G. Lundeen, John A. Kepler, Chunyang Jin, Margaret Kiddoe, Zhihua Sui, Govindarajan Manikumar
Publikováno v:
ChemInform. 39
Autor:
George F. Allan, Margaret Kiddoe, Elizabeth Lombardi, Philip J. Rybczynski, Donald W. Combs, Muh-Tsann Lai, Donna Haynes-Johnson, Stephen S. Palmer, Gary D. Hodgen, Patricia Kraft, Phyllis Pedersen, Amy Hutchins, Carolyn Campen
Publikováno v:
The Journal of steroid biochemistry and molecular biology. 75(1)
We have characterized a series of nonsteroidal progesterone receptor ligands, the tetrahydropyridazines. Compounds in this series, exemplified by RWJ 26819, demonstrate high affinity and unprecedented specificity for the progesterone receptor relativ