Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Margaret J. Degnan"'
Autor:
Hung Jocelyn H, Leslie M. Werbel, Margaret J. Degnan, Daniel F. Ortwine, Dennis Joseph Mcnamara, Susan E. Uhlendorf, Stephen J. Kesten
Publikováno v:
Journal of Medicinal Chemistry. 35:3429-3447
To improve upon the activity and properties of the 3-aryl-7-chloro-3,4- dihydro-1,9(2H,10H)-acridinediones, a variety of 1-[(alkylamino)alkylene]imino derivatives (3) were prepared and shown to be highly active antimalarial agents in both rodents and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ef56274b649c8c9999d0c71996f199e
https://doi.org/10.1021/jm00097a001
https://doi.org/10.1021/jm00097a001
Autor:
Leslie M. Werbel, Margaret J. Degnan
Publikováno v:
Journal of Medicinal Chemistry. 30:2151-2154
A variety of analogues of 2,4-diamino-6-[(aryl)thio]quinazolines with known antimalarial properties were prepared wherein the 4-amino group was replaced by hydrazino and hydroxyamino moieties. Such changes were found to reduce markedly the antimalari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1fde565c4730d64591b58093dc776fb3
https://doi.org/10.1021/jm00394a038
https://doi.org/10.1021/jm00394a038
Autor:
Barbara Whitney, Judith L. Johnson, Dennis Joseph Mcnamara, Leslie M. Werbel, Norman L. Colbry, Margaret J. Degnan
Publikováno v:
Journal of Heterocyclic Chemistry. 16:881-894
The synthesis of a series of N,N-dialkyl-6-(substituted phenyl)-1,2,4,5-tetrazin-3-amines (IV) by two routes is described. The first route (Scheme I) involved the oxidative cyclization of formazans (II) to 3-bromo-6-(substituted phenyl)-1,2,4,5-tetra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ad3c1580264a728998faa4818e3bfd2
https://doi.org/10.1002/jhet.5570160511
https://doi.org/10.1002/jhet.5570160511