Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Margaret J. DeBell"'
Autor:
Priya Chaudhary, Thomas S. Scanlan, Edvinas Pocius, Brooke A. Napier, Gail Marracci, Hannah Miller, Skylar J. Ferrara, Evan Calkins, Dennis Bourdette, Margaret J. DeBell, Ben Emery
Publikováno v:
Cell Chem Biol
bioRxiv
bioRxiv
Triggering receptor expressed on myeloid cells-2 (TREM2) is a cell surface receptor on macrophages and microglia that senses and responds to disease associated signals to regulate the phenotype of these innate immune cells. The TREM2 signaling pathwa
Autor:
Mitra D. Shokat, Tania Banerji, Margaret J. DeBell, Lisa L. Kirkemo, Thomas S. Scanlan, Meredith D. Hartley
Publikováno v:
Cell Chem Biol
X-linked adrenoleukodystrophy (X-ALD) is a genetic disease involving loss of function of the peroxisomal transporter ABCD1, resulting in an inappropriate increase in very long chain fatty acid (VLCFA) concentrations throughout the body. Elevated leve
Autor:
Priya Chaudhary, Lisa L. Kirkemo, Meredith D. Hartley, Edvinas Pocius, Dennis Bourdette, Mitra D. Shokat, Tapasree Banerji, Danielle Galipeau, Gail Marracci, Margaret J. DeBell, Ian J. Tagge, Thomas S. Scanlan, Evan Calkins, Shelby Van Leuven, J. Matthew Meinig, Skylar J. Ferrara, Tania Banerji, Hannah Miller, Ben Emery
Publikováno v:
JCI Insight. 4
Oligodendrocyte processes wrap axons to form neuroprotective myelin sheaths, and damage to myelin in disorders, such as multiple sclerosis (MS), leads to neurodegeneration and disability. There are currently no approved treatments for MS that stimula