Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Margaret H. O'Connor"'
Autor:
Kristen E. Rhodin, Denisse Porras Fimbres, Danielle N. Burner, Shayna Hollander, Margaret H. O’Connor, Georgia M. Beasley
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
The presence of lymph node metastases is a well-studied prognostic factor for cutaneous melanoma. Characterization of melanoma lymph node metastases and their association with survival in multiple, large observational studies has led to recognition o
Externí odkaz:
https://doaj.org/article/01f1818af0a84a8fbe989ea01c5b5d32
Autor:
Margaret H. O’Connor, Roshell Muir, Marita Chakhtoura, Michael Fang, Eirini Moysi, Susan Moir, Alison J. Carey, Alyssa Terk, Carmen N. Nichols, Talibah Metcalf, Constantinos Petrovas, Mark J. Cameron, Virginie Tardif, Elias K. Haddad
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
Margaret O’Connor et al. report a new Innate Lymphoid Cell population in human tonsils and lymph nodes that inhibit the functional interaction of follicular helper T cells and germinal center B cells. They show that this cell population is expanded
Externí odkaz:
https://doaj.org/article/a866230b1fdc4b2fb508ecc62a24397c
Autor:
Stephanie M. Matt, Emily A. Nickoloff-Bybel, Yi Rong, Kaitlyn Runner, Hannah Johnson, Margaret H. O’Connor, Elias K. Haddad, Peter J. Gaskill
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Despite widespread use of antiretroviral therapy (ART), HIV remains a major public health issue. Even with effective ART many infected individuals still suffer from the constellation of neurological symptoms now known as neuroHIV. These symptoms can
Externí odkaz:
https://doaj.org/article/6dd73394af4f49e1bfabab1ce234e598
Autor:
Susan Moir, Talibah Metcalf, Margaret H. O’Connor, Eirini Moysi, Marita Chakhtoura, Alison J. Carey, Virginie Tardif, Mike Fang, Constantinos Petrovas, Mark J. Cameron, Carmen N. Nichols, Alyssa R. Terk, Elias K. Haddad, Roshell Muir
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
Innate Lymphoid Cells (ILCs) are immune cells typically found on mucosal surfaces and in secondary lymphoid organs where they regulate the immune response to pathogens. Despite their key role in the immune response, there are still fundamental gaps i
Autor:
Virginie Tardif, William F. Sutton, Ogan K. Kumova, Nancy L. Haigwood, Marita Chakhtoura, Delphine C. Malherbe, Michele A. Kutzler, Ebony N. Gary, Elias K. Haddad, Margaret H. O’Connor
Publikováno v:
Vaccine
Adenosine deaminase-1 (ADA-1) plays both enzymatic and non-enzymatic roles in regulating immune cell function. Mutations in the ADA1 gene account for 15% of heritable severe-combined immunodeficiencies. We determined previously that ADA1 expression d
Autor:
Susan Moir, Rafael Cubas, Aarthi Talla, Margaret H. O’Connor, Carmen N. Nichols, Elias K. Haddad, Virginie Tardif, Brian Richardson, Mark J. Cameron, Mike Fang, Marita Chakhtoura
Publikováno v:
PLoS Pathogens, Vol 17, Iss 7, p e1009732 (2021)
PLoS Pathogens
PLoS Pathogens, 2021, 17 (7), pp.e1009732. ⟨10.1371/journal.ppat.1009732⟩
PLoS Pathogens, Public Library of Science, 2021, 17 (7), pp.e1009732. ⟨10.1371/journal.ppat.1009732⟩
PLoS Pathogens
PLoS Pathogens, 2021, 17 (7), pp.e1009732. ⟨10.1371/journal.ppat.1009732⟩
PLoS Pathogens, Public Library of Science, 2021, 17 (7), pp.e1009732. ⟨10.1371/journal.ppat.1009732⟩
We have recently demonstrated that the function of T follicular helper (Tfh) cells from lymph nodes (LN) of HIV-infected individuals is impaired. We found that these cells were unable to provide proper help to germinal center (GC)-B cells, as observe
Autor:
Eishi Noguchi, Koji Tanaka, Jasmine D. Peake, Hiroshi Nakagawa, Chiaki Noguchi, Amber Theriault, Shivani Sheth, Margaret H. O’Connor, Baicheng Lin
Publikováno v:
Molecular Oncology
Individuals with Fanconi anemia (FA), a rare genetic bone marrow failure syndrome, have an increased risk of young‐onset head and neck squamous cell carcinomas (SCCs) and esophageal SCC. The FA DNA repair pathway is activated upon DNA damage induce
Publikováno v:
Advanced Concepts in Human Immunology: Prospects for Disease Control ISBN: 9783030339456
Chimeric antigen receptor (CAR) T cells have emerged as a potential groundbreaking treatment for patients with advanced B-cell and other hematologic malignancies. CAR T cells recognize and eliminate tumor cells via cytotoxic killing, independent of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0569e0d1f10a2e053ab35bd8bb316617
https://doi.org/10.1007/978-3-030-33946-3_7
https://doi.org/10.1007/978-3-030-33946-3_7
Autor:
Paola Vinci, Elena Garcia-Martinez, Margaret H. O’Connor, Anastasiya Egorova, Jason Kuttiyara, Viktor Arnhold, Doris M. Ponce, Alan M. Hanash
Publikováno v:
The Journal of Immunology. 204:87.14-87.14
Innate lymphoid cells (ILCs) are associated with protective mucosal responses after allogeneic bone marrow transplantation (allo-BMT). However, the specific in vivo roles of ILCs after BMT remain unclear. We thus sought to characterize the kinetics a
Autor:
Marita Chakhtoura, Mike Fang, Rafael Cubas, Margaret H O'Connor, Carmen N Nichols, Brian Richardson, Aarthi Talla, Susan Moir, Mark J Cameron, Virginie Tardif, Elias K Haddad
Publikováno v:
PLoS Pathogens, Vol 17, Iss 7, p e1009732 (2021)
We have recently demonstrated that the function of T follicular helper (Tfh) cells from lymph nodes (LN) of HIV-infected individuals is impaired. We found that these cells were unable to provide proper help to germinal center (GC)-B cells, as observe
Externí odkaz:
https://doaj.org/article/291573c3b8f04ece8dfdb7a54f6e1523