Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Margaret Guo"'
Autor:
Smarajit Mondal, Muthukumar Ramanathan, Weili Miao, Robin M. Meyers, Deepti Rao, Vanessa Lopez-Pajares, Zurab Siprashvili, David L. Reynolds, Douglas F. Porter, Ian Ferguson, Poornima Neela, Yang Zhao, Lindsey M. Meservey, Margaret Guo, Yen-Yu Yang, Lin Li, Yinsheng Wang, Paul A. Khavari
Publikováno v:
Nat Methods
DNA-protein interactions mediate physiologic gene regulation and may be altered by DNA variants linked to polygenic disease. To enhance the speed and signal-to-noise ratio (SNR) in the identification and quantification of proteins associated with spe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1452d2bebadbf1c8bd27e79e4a0d825d
https://doi.org/10.1038/s41592-022-01552-w
https://doi.org/10.1038/s41592-022-01552-w
Publikováno v:
Briefings in Bioinformatics
Network biology is useful for modeling complex biological phenomena; it has attracted attention with the advent of novel graph-based machine learning methods. However, biological applications of network methods often suffer from inadequate follow-up.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0eef46c358d00f3ef26860444e94b10c
https://pubmed.ncbi.nlm.nih.gov/34849568
https://pubmed.ncbi.nlm.nih.gov/34849568
Autor:
Arun P. Wiita, Bryant Dm, Margaret Guo, Guanqing Ou, FuiBoon Kai, Wei Guo, Viasnoff, Sophie Dumont, Dorit Hanein, Ravi Radhakrishnan, Yisu Han, Alexandra F. Long, Hai Huang, Andrew M. Leidal, Valerie M. Weaver, Richard W. Tourdot, Niels Volkmann, Guido Gaietta, Mark F. Swift, Jason J. Northey, Connor Stashko
Primary tissue organoids and cell spheroids recapitulate tissue physiology with remarkable fidelity. We investigated how engagement with a three dimensional laminin-rich extracellular matrix supports the polarized, stress resilient spheroid phenotype
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa1e3be97f3b2adb21e8286ebf08cec3
https://doi.org/10.1101/2021.07.14.452329
https://doi.org/10.1101/2021.07.14.452329
Publikováno v:
Nat Rev Genet
Single-cell RNA sequencing (scRNA-seq) identifies cell subpopulations within tissue but does not capture their spatial distribution nor reveal local networks of intercellular communication acting in situ. A suite of recently developed techniques that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef45d80daf3a377b20b6340b147a7eb4
https://pubmed.ncbi.nlm.nih.gov/34145435
https://pubmed.ncbi.nlm.nih.gov/34145435
Autor:
Yen-Yu Yang, Ronald L. Shanderson, Muthukumar Ramanathan, Jordan M. Meyers, Paul A. Khavari, Yinsheng Wang, Catherine A. Blish, David Reynolds, Aimee Beck, Deepti Rao, Yang Zhao, Margaret Guo, Ian D Ferguson, Weili Miao, Laura K. Donohue, Xue Yang
Publikováno v:
PLoS Pathogens, Vol 17, Iss 10, p e1009412 (2021)
PLoS Pathogens
bioRxiv
PLoS Pathogens
bioRxiv
Viral proteins localize within subcellular compartments to subvert host machinery and promote pathogenesis. To study SARS-CoV-2 biology, we generated an atlas of 2422 human proteins vicinal to 17 SARS-CoV-2 viral proteins using proximity proteomics.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::effd24503a8fda690940ab94fd8c31b7
https://doi.org/10.1101/2021.02.23.432450
https://doi.org/10.1101/2021.02.23.432450
Publikováno v:
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing
Scopus-Elsevier
PSB
Scopus-Elsevier
PSB
One in five Americans experience mental illness, and roughly 75% of psychiatric prescriptions do not successfully treat the patient’s condition. Extensive evidence implicates genetic factors and signaling disruption in the pathophysiology of these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::589a47b73cc13a28c80191a05264af14
https://pubmed.ncbi.nlm.nih.gov/31797637
https://pubmed.ncbi.nlm.nih.gov/31797637
Publikováno v:
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing
Millions of Americans are affected by rare diseases, many of which have poor survival rates. However, the small market size of individual rare diseases, combined with the time and capital requirements of pharmaceutical R&D, have hindered the developm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::424bcefe831b3e11594d1a8fb7c54e6a
https://pubmed.ncbi.nlm.nih.gov/31797619
https://pubmed.ncbi.nlm.nih.gov/31797619
Autor:
William W. Lu, Frankie Leung, Margaret Guo, Christian X Fang, Sloan Austin Kulper, Kam Yim Sze, Xiaodan Ren, Alfonso H.W. Ngan, Kerstin Schneider
Publikováno v:
Journal of the Mechanical Behavior of Biomedical Materials. 80:128-136
Many features of orthopaedic implants have been previously examined regarding their influence on migration in trabecular bone under axial loading, with screw thread design being one of the most prominent examples. There has been comparatively little
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eebfb42da8f14f903f4acd0d066f066f
https://doi.org/10.1016/j.jmbbm.2018.01.025
https://doi.org/10.1016/j.jmbbm.2018.01.025
Autor:
Andrew L. Ji, Margaret Guo, Daniel Sunwook Kim, Adam J. Rubin, Sumaira Z. Aasi, Joakim Lundeberg, Kim Thrane, T. Hollmig, Paul A. Khavari
Publikováno v:
Journal of Investigative Dermatology. 141:S17
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::860fdc7f5f631c0fff03656cd32bc029
https://doi.org/10.1016/j.jid.2021.02.111
https://doi.org/10.1016/j.jid.2021.02.111
Autor:
Paul A. Khavari, Margaret Guo, Vanessa Lopez-Pajares, Yang Zhao, Gayatri Gowrishankar, Laura K. Donohue, Aparna Bhaduri, A. Guerrero, Sanjiv S. Gambhir
Publikováno v:
Journal of Investigative Dermatology. 141:S24
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::81daad4f50a34ae621438d32a935af4d
https://doi.org/10.1016/j.jid.2021.02.151
https://doi.org/10.1016/j.jid.2021.02.151