Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Margaret G Filbert"'
Publikováno v:
Annals of the New York Academy of Sciences. 890:330-335
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54f29bec45364d112acaaca2cb99ad55
https://doi.org/10.1111/j.1749-6632.1999.tb08010.x
https://doi.org/10.1111/j.1749-6632.1999.tb08010.x
Autor:
Mauricio Montal, James P. Apland, J. A. Biser, Michael Adler, Margaret G. Filbert, Antonio Ferrer-Montiel
Publikováno v:
Journal of Applied Toxicology. 19:S23-S26
Botulinum neurotoxin serotypes A and E (BoNT/A and BoNT/E) block neurotransmitter release, presumably by cleaving SNAP-25, a protein involved in docking of synaptic vesicles with the presynaptic plasma membrane. Three excitation-secretion uncoupling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3228b9ceede75e43fc321297b20b7fd2
https://doi.org/10.1002/(sici)1099-1263(199912)19:1+3.0.co
https://doi.org/10.1002/(sici)1099-1263(199912)19:1+
Publikováno v:
Annals of the New York Academy of Sciences. 890:505-514
Neuroprotective effects of HU-211 (dexanabinol), a synthetic nonpsychotropic analog of tetrahydrocannabinol, on brain damage resulting from soman-induced seizures were examined in male Sprague-Dawley rats challenged with 1.6 LD50 soman. At 5 or 40 mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfcfeccea4689416dcf46f4527e6655b
https://doi.org/10.1111/j.1749-6632.1999.tb08032.x
https://doi.org/10.1111/j.1749-6632.1999.tb08032.x
Publikováno v:
Journal of Applied Toxicology. 19:S13-S17
The binding activity of a rabbit polyclonal antiserum raised against a 51-residue peptide (P51) homologous to human VAMP2 (residues 44–94) was examined. Human VAMP2 is an 18-kDa protein located on the external membrane of small synaptic vesicles an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::449c57b0ea12bd99abd28660008eddce
https://doi.org/10.1002/(sici)1099-1263(199912)19:1+3.0.co
https://doi.org/10.1002/(sici)1099-1263(199912)19:1+
Publikováno v:
International Journal of Toxicology. 16:103-118
The effects on membrane fluidity of inhibitors of acetylcholinesterase (A ChE) as well as those of certain nicotinic agonists have been examined in synaptosomes prepared from the electroplax of Torpedo californica. Electron paramagnetic resonance (EP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46ccc592f58a6a8979ee983fdab75672
https://doi.org/10.1080/109158197227215
https://doi.org/10.1080/109158197227215
Autor:
Catherine D. Smith, Lee J. Martin, Margaret G. Filbert, Gerald P. H. Ballough, Frank J. Cann, Jeffry S. Forster, C.E. Kling, J.S. Graham, Sorabe Phann
Publikováno v:
Journal of Neuroscience Methods. 61:23-32
We have assessed the efficacy of MAP-2 immunohistochemistry as a marker of seizure-related brain damage and its suitability for quantitation of the damage using densitometric and morphometric image analysis. Seizures were produced in rats by administ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f797b429c480d6ead4dc384406cbe8de
https://doi.org/10.1016/0165-0270(95)00019-q
https://doi.org/10.1016/0165-0270(95)00019-q
Publikováno v:
Archives of Toxicology. 69:384-390
An in vitro mammalian model neuronal system to evaluate the intrinsic toxicity of soman and other neurotoxicants as well as the efficacy of potential countermeasures was investigated. The link between soman toxicity, glutamate hyperactivity and neuro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6adaa4531a2e5a80edb697052334b1d1
https://doi.org/10.1007/s002040050188
https://doi.org/10.1007/s002040050188
Autor:
Jeffry S. Forster, Frank J. Cann, Leland W. Dochterman, Margaret G. Filbert, Catherine D. Smith, Sorabe Phann
Publikováno v:
Drug Development Research. 30:45-53
The effect of intravenous mannitol on soman-induced neuropathology and cardio-myopathy was studied in rats. Soman, an organophosphorus agent, irreversibly inhibits total body acetylcholinesterase and induces a cholinototoxic syndrome in rats which re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b4f10d0f5cf98a7a07a90c8409099e45
https://doi.org/10.1002/ddr.430300107
https://doi.org/10.1002/ddr.430300107
Autor:
Margaret G. Filbert, Michael Adler
Publikováno v:
FEBS Letters. 267:107-110
The role of butyrylcholinesterase (BuChE) and acetylcholinesterase (AChE) in regulating acetylcholine (ACh) lifetime was investigated by use of selective cholinesterase (ChE) inhibitors. Addition of 1 μM tetraisopropylpyrophosphoramide (iso-OMPA) le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa9da1ab46b98676607fc84f92aa3c02
https://doi.org/10.1016/0014-5793(90)80300-8
https://doi.org/10.1016/0014-5793(90)80300-8
Autor:
Fat-Chun T. Chang, Margaret G. Filbert, Everette T. Beers, Daniel L. Rickett, Robert E. Foster
Publikováno v:
Toxicology and Applied Pharmacology. 102:233-250
Soman-induced respiratory failure was investigated in awake, behaving guinea pigs chronically instrumented to allow concurrent recordings of medullary respiratory-related unit (RRU) activity, diaphragm electromyogram (DEMG), and electrocorticogram. R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::658217b5b59f67abfb69f4e9d5cd3569
https://doi.org/10.1016/0041-008x(90)90023-n
https://doi.org/10.1016/0041-008x(90)90023-n