No alteration in NK function or ζ chain expression in NK and T cells of cervical cancer patients

Autor: Peter L. Stern, Henry C Kitchener, Margaret F Duggan-Keen, Toli S Onon

Publikováno v: Gynecologic Oncology. 89:120-128

Objectives To investigate in vitro natural killer (NK) cell activity and expression of signal-transducing ζ chains in patients with cervical cancer. Patients and methods Experiments were performed with frozen lymphocytes from patients at all disease

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2599bcc1d27c49d22991052298165ee7
https://doi.org/10.1016/s0090-8258(03)00009-x

Human papillomavirus type 16 E6/E7-specific cytotoxic T lymphocytes in women with cervical neoplasia

Autor: Simon N. Stacey, Marij J. Stukart, Hetty J. Bontkes, Peter L. Stern, Margaret F. Duggan-Keen, Leszek K. Borysiewicz, René H.M. Verheijen, Jan M. M. Walboomers, Chris J.L.M. Meijer, Rik J. Scheper, Tanja D. de Gruijl, Stephen Man, Adrie J.C. van den Muysenberg

Publikováno v: Bontkes, H J, de Gruijl, T D, van den Muysenberg, A J C, Verheijen, R H M, Stukart, M J, Meijer, C J L M, Scheper, R J, Stacey, S N, Duggan-Keen, M F, Stern, P L, Man, S, Borysiewicz, L K & Walboomers, J M M 2000, ' Human papillomavirus type 16 E6/E7-specific cytotoxic T lymphocytes in women with cervical neoplasia ', International Journal of Cancer, vol. 88, no. 1, pp. 92-98 . https://doi.org/10.1002/1097-0215(20001001)88:1<92::AID-IJC15>3.0.CO;2-E
International Journal of Cancer, 88(1), 92-98. Wiley-Liss Inc.

Infection with oncogenic human papillomavirus (HPV) types is associated with the development of cervical neoplasia (CIN). The E6 and E7 oncoproteins are constitutively expressed in these lesions and are therefore putative targets for the immune respo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0dd1593996e18c34b41165b3a138ddf
http://www.scopus.com/inward/record.url?scp=0033863513&partnerID=8YFLogxK

Immune responses against human papillomavirus (HPV) type 16 virus-like particles in a cohort study of women with cervical intraepithelial neoplasia. I. Differential T-helper and IgG responses in relation to HPV infection and disease outcome

Autor: R.J. Scheper, Theo J.M. Helmerhorst, J. M. M. Walboomers, R.H.M. Verheijen, M. J. Stukart, Esther W. M. Kueter, T. D. De Gruijl, Peter L. Stern, Pierre Coursaget, C. Dupuy, Margaret F Duggan-Keen, C. J. L. M. Meijer, H. J. Bontkes

Publikováno v: Journal of General Virology
Journal of General Virology, Microbiology Society, 1999, 80 (2), pp.399-408. ⟨10.1099/0022-1317-80-2-399⟩
Journal of General Virology, 80, 399-408. Microbiology Society
de Gruijl, T D, Bontkes, H J, Walboomers, J M, Coursaget, P, Stukart, M J, Dupuy, C, Kueter, E, Verheijen, R H, Helmerhorst, T J, Duggan-Keen, M F, Stern, P L, Meijer, C J & Scheper, R J 1999, ' Immune responses against human papillomavirus (HPV) type 16 virus-like particles in a cohort study of women with cervical intraepithelial neoplasia. I. Differential T-helper and IgG responses in relation to HPV infection and disease outcome ', Journal of General Virology, vol. 80 ( Pt 2), pp. 399-408 . https://doi.org/10.1099/0022-1317-80-2-399
Journal of General Virology, 80 ( Pt 2), 399-408. Society for General Microbiology

T-helper (Th) cell-dependent IL-2 production and plasma IgG responses to virus-like particles consisting of the human papillomavirus type 16 (HPV-16) major capsid protein L1 (L1-VLP) were determined in patients with cytological evidence of cervical i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51a25aed73106e928eae8a865ce65e67
https://doi.org/10.1099/0022-1317-80-2-399

Comparative analysis of cell surface antigens expressed by cell lines derived from human germ cell tumours

Autor: Ivan Damjanov, Martin F. Pera, José Luis Millán, Peter W. Andrews, Peter L. Stern, Leendert H. J. Looijenga, Niels E. Skakkebæk, Aleksander Giwercman, Hans-J. Schmoll, Masumi Sawada, J. Wolter Oosterhuis, Jun-ichi Hata, Wilhelm van Putten, Margaret F Duggan-Keen, Alexander von Keitz, Jochen Casper

Publikováno v: International Journal of Cancer. 66:806-816

The pattern of cell surface antigen expression of a set of cell lines derived from human germ cell tumours and corresponding to various cell phenotypes found within these tumours was studied using immunofluorescence. Twenty-two different antibodies w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5a40c62f167c41eacf70b762489385e8
https://doi.org/10.1002/(sici)1097-0215(19960611)66:6<806::aid-ijc17>3.0.co

Frequency of down-regulation of individual HLA-A and -B alleles in cervical carcinomas in relation to TAP-1 expression

Autor: P. J. F. Snijders, Jan M. M. Walboomers, F. V. Cromme, Robin D Hunter, Margaret F Duggan-Keen, Patrick Keating, Peter L. Stern, Philip A. Dyer

Publikováno v: British Journal of Cancer

The development of cervical carcinoma is strongly associated with specific types of human papillomaviruses (HPVs). A role for cellular immunity in cervical disease is supported by the increased occurrence of HPV-associated lesions in immunosuppressed

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d8a48e48a5201a87f5e0a9b4b3b6d5c
http://europepmc.org/articles/PMC2033975