Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Margaret E. Fleming"'
Autor:
Howard A. Burris, Lieping Chen, Patricia LoRusso, Muaiad Kittaneh, Jeffrey R. Infante, Solomon Langermann, Stanley Pillemer, Margaret E. Fleming, Sara Brett, John D. Powderly, Martin Devenport, Rena May, Shannon Marshall, Drew M. Pardoll, James F. Smothers, Jessica Houston Grice
Publikováno v:
Journal of Clinical Oncology. 31:3044-3044
3044 Background: PD-1/B7-H1 (PD-L1) axis blockade can reinvigorate T cells, and overcome tumor immune evasion of multiple tumor types. AMP-224 is the first recombinant B7-DC-Fc fusion protein tested in patients that binds to and modulates the PD-1 ax
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69c19b1baf0859d4237a6773531ea85f
https://doi.org/10.1200/jco.2013.31.15_suppl.3044
https://doi.org/10.1200/jco.2013.31.15_suppl.3044
Autor:
Lieping Chen, Stanley Pillemer, Muaiad Kittaneh, Sara Brett, Martin Devenport, Rena J. May, Shannon Marshall, John D. Powderly, Jeffrey R. Infante, Jessica Houston Grice, Howard A. Burris, Margaret E. Fleming, Solomon Langermann, Drew M. Pardoll, James F. Smothers, Patricia LoRusso
Publikováno v:
Cancer Research. 73:LB-193
Background: AMP-224 is a recombinant Fc fusion protein that binds to the programmed death-1 (PD-1) receptor. This first-in-human study was designed to determine the safety, tolerability, maximum tolerated dose (MTD), pharmacokinetic (PK) profile, pha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f519d7fa1923da20a5763a076001b47c
https://doi.org/10.1158/1538-7445.am2013-lb-193
https://doi.org/10.1158/1538-7445.am2013-lb-193