Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Margaret E Choi"'
Autor:
Kathleen J. Propert, Xiangping Lu, Margaret E Choi, Frederick J. Balzer, Shira T. Rosenblum, Daniel J VanBelzen, Leonard T. Su, Peter P. Nghiem, Joe N. Kornegay, Marilyn A. Mitchell, Mihail Petrov, Shangzhen Zhou, Benjamin W. Kozyak, Christopher D. Greer, Alock Malik, Yafeng Song, Andrew F. Mead, Ranjith K Krishnankutty, Robert A. French, Hansell H. Stedman, Emanuele Loro, Leon Morales, Tejvir S. Khurana
Publikováno v:
Nature Medicine. 25:1505-1511
The essential product of the Duchenne muscular dystrophy (DMD) gene is dystrophin1, a rod-like protein2 that protects striated myocytes from contraction-induced injury3,4. Dystrophin-related protein (or utrophin) retains most of the structural and pr
Autor:
Yafeng, Song, Leon, Morales, Alock S, Malik, Andrew F, Mead, Christopher D, Greer, Marilyn A, Mitchell, Mihail T, Petrov, Leonard T, Su, Margaret E, Choi, Shira T, Rosenblum, Xiangping, Lu, Daniel J, VanBelzen, Ranjith K, Krishnankutty, Frederick J, Balzer, Emanuele, Loro, Robert, French, Kathleen J, Propert, Shangzhen, Zhou, Benjamin W, Kozyak, Peter P, Nghiem, Tejvir S, Khurana, Joe N, Kornegay, Hansell H, Stedman
Publikováno v:
Mol Ther
The essential product of the Duchenne muscular dystrophy (DMD) gene is dystrophin
Autor:
Yafeng Song, Andrew F. Mead, Leonard T. Su, Hansell H. Stedman, Mihail Petrov, Marilyn A. Mitchell, Margaret E Choi, Joe N. Kornegay, Xiangping Lu, Daniel J VanBelzen, Maxwell Joffe, Alock Malik, Tejvir Tejvir Khurana
Publikováno v:
Molecular Therapy. 24:S37
The majority of mutations causing Duchenne muscular dystrophy (DMD) are multi-exon, frameshifting deletions, complicating therapy with recombinant dystrophin because of the potential for chronic immune recognition of the “non-self” protein. The p