Zobrazeno 1 - 10
of 138
pro vyhledávání: '"Margaret Dah-Tsyr Chang"'
Autor:
Hsien-Neng Huang, Chun-Wei Kuo, Yu-Ling Hung, Chia-Hung Yang, Yu-Han Hsieh, Yu-Chieh Lin, Margaret Dah-Tsyr Chang, Yen-Yin Lin, Jen-Chung Ko
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Assessing programmed death ligand 1 (PD-L1) expression through immunohistochemistry (IHC) is the golden standard in predicting immunotherapy response of non-small cell lung cancer (NSCLC). However, observation of heterogeneous PD-L1 distribu
Externí odkaz:
https://doaj.org/article/869d680d9eed43efb3829c3934160895
Autor:
Pei-Wen Huang, Hsu Ouyang, Bang-Yi Hsu, Yu-Ruei Chang, Yu-Chieh Lin, Yung-An Chen, Yu-Han Hsieh, Chien-Chung Fu, Chien-Feng Li, Ching-Hung Lin, Yen-Yin Lin, Margaret Dah-Tsyr Chang, Tun-Wen Pai
Publikováno v:
Heliyon, Vol 9, Iss 2, Pp e13171- (2023)
Hematoxylin and eosin (H&E) staining is the gold standard for tissue characterization in routine pathological diagnoses. However, these visible light dyes do not exclusively label the nuclei and cytoplasm, making clear-cut segmentation of staining si
Externí odkaz:
https://doaj.org/article/4c7cee8caa764213bd5f05dbe6b4f5b2
Autor:
Li-Yu Lee, Cheng-Han Yang, Yu-Chieh Lin, Yu-Han Hsieh, Yung-An Chen, Margaret Dah-Tsyr Chang, Yen-Yin Lin, Chun-Ta Liao
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundPerineural invasion (PNI), a form of local invasion defined as the ability of cancer cells to invade in, around, and through nerves, has a negative prognostic impact in oral cavity squamous cell carcinoma (OCSCC). Unfortunately, the diagnos
Externí odkaz:
https://doaj.org/article/2bd61f31d143410ea2066b9b1c73d5ce
Autor:
Ping-Hsueh Kuo, Yi-Hsien Teng, Ann-Lun Cin, Wen Han, Pei-Wan Huang, Lily Hui-Ching Wang, Yu-Ting Chou, Jia-Ling Yang, Yun-Long Tseng, Minhsiung Kao, Margaret Dah-Tsyr Chang
Publikováno v:
Drug Delivery, Vol 27, Iss 1, Pp 542-555 (2020)
Nanoparticles (NPs), such as liposomes, effectively evade the severe toxicity of unexpected accumulation and passively shuttle drugs into tumor tissues by enhanced permeability and retention. In the case of non-small cell lung cancer and pancreatic d
Externí odkaz:
https://doaj.org/article/e52312b323f24bb8aa40cd945a0e992d
Autor:
Tse-Kai Fu, Ping-Hsueh Kuo, Yen-Chang Lu, Hsing-Ni Lin, Lily Hui-Ching Wang, Yu-Chun Lin, Yu-Chen Kao, Huey-Min Lai, Margaret Dah-Tsyr Chang
Publikováno v:
Biomolecules, Vol 10, Iss 1, p 101 (2020)
Cosmeceutical peptides have become an important topic in recent decades in both academic and industrial fields. Many natural or synthetic peptides with different biological functions including anti-ageing, anti-oxidation, anti-infection and anti-pigm
Externí odkaz:
https://doaj.org/article/adcbfbdcd5f24750a153d5acf491c83b
Autor:
Tse-Kai Fu, Sim-Kun Ng, Yi-En Chen, Yuan-Chuan Lee, Fruzsina Demeter, Mihály Herczeg, Anikó Borbás, Cheng-Hsun Chiu, Chung-Yu Lan, Chyi-Liang Chen, Margaret Dah-Tsyr Chang
Publikováno v:
Marine Drugs, Vol 17, Iss 6, p 355 (2019)
More than 80% of infectious bacteria form biofilm, which is a bacterial cell community surrounded by secreted polysaccharides, proteins and glycolipids. Such bacterial superstructure increases resistance to antimicrobials and host defenses. Thus, to
Externí odkaz:
https://doaj.org/article/1e491604a8c842ff8d8c782b8167ef94
Publikováno v:
Neurobiology of Disease, Vol 58, Iss , Pp 13-18 (2013)
Amyotrophic lateral sclerosis (ALS) is a complicate and progressive onset devastating neurodegenerative disease. Its pathogenic mechanisms remain unclear and there is no specific test for diagnosis. For years, researchers have been vigorously searchi
Externí odkaz:
https://doaj.org/article/2a3bfd3c5e6b4bd68dca1e7cdf0ae39d
Autor:
Margaret Dah-Tsyr Chang, Ping-Hsueh Kuo, Tan-chi Fan, Chien-Jung Chen, Hao-Teng Chang, Yuan-Chuan Lee, Ta-Jen Hung, Noboru Tomiya, Wei-Tang Chang
Publikováno v:
International Journal of Molecular Sciences, Vol 14, Iss 9, Pp 19067-19085 (2013)
Human eosinophil derived neurotoxin (EDN), a granule protein secreted by activated eosinophils, is a biomarker for asthma in children. EDN belongs to the human RNase A superfamily possessing both ribonucleolytic and antiviral activities. EDN interact
Externí odkaz:
https://doaj.org/article/fdc004b2e790472586c404ca9b18fe76
Autor:
Shun-Long Weng, Shing-Jyh Chang, Yi-Chieh Cheng, Hua-Yong Wang, Tao-Yeuan Wang, Margaret Dah-Tsyr Chang, Hsei-Wei Wang
Publikováno v:
Taiwanese Journal of Obstetrics & Gynecology, Vol 50, Iss 4, Pp 447-457 (2011)
Objective: Mesenchymal stem cells (MSCs) are an attractive source for providing the cells necessary for regenerating damaged tissues. Fetal MSCs (fMSCs) are known to proliferate fast and have an excellent osteogenic capacity, yet the underlying mecha
Externí odkaz:
https://doaj.org/article/a34dc2d0db1146669a42b3d9d5c326f5
Publikováno v:
Taiwanese Journal of Obstetrics & Gynecology, Vol 48, Iss 4, Pp 356-369 (2009)
Objective: Somatic CD34+ CD38− stem cells can differentiate into cells of hematopoietic and endothelial lineages and have been clinically used to treat diseases. These stem cells can be obtained from cord blood (CB), bone marrow or granulocyte-macr
Externí odkaz:
https://doaj.org/article/de57d24dcc0243b2ba8951e5fd867179