Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Margaret D. Myers"'
Publikováno v:
Developmental cell, vol 37, iss 2
Membrane remodeling by BAR (Bin, Amphiphysin, RVS) domain-containing proteins, such as endophilins and amphiphysins, is integral to the process of endocytosis. However, little is known about the regulation of endocytic BAR domain activity. We have id
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0c70c51133a48a6e41ea2351274f406
https://doi.org/10.1016/j.devcel.2016.03.012
https://doi.org/10.1016/j.devcel.2016.03.012
Autor:
Gregory S. Payne, Margaret D. Myers
Publikováno v:
The Journal of cell biology, vol 216, iss 2
The Journal of Cell Biology
The Journal of Cell Biology
VPS13 proteins are widely conserved in eukaryotes and associated with human neurodegenerative and neurodevelopmental diseases. De et al. describe the lipid specificity and structure of yeast Vps13p, providing insight into its role in both TGN late en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9666d91fe60bb6a624bcbc44d82c4cbb
https://escholarship.org/uc/item/2852c3rz
https://escholarship.org/uc/item/2852c3rz
Autor:
Margaret D. Myers, Carmen White, Arthur Weiss, Hamid Band, Leonard L. Dragone, Tomasz Sosinowski, Hua Gu
Publikováno v:
Nature Immunology. 7:57-66
The adaptor molecule SLAP and E3 ubiquitin ligase c-Cbl each regulate expression of T cell receptor (TCR)-CD3 on thymocytes. Here we provide genetic and biochemical evidence that both molecules function in the same pathway. TCR-CD3 expression was sim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca3ca5db8213fdff648b164194843cd2
https://doi.org/10.1038/ni1291
https://doi.org/10.1038/ni1291
Publikováno v:
Immunological reviews. 232(1)
Src-like adapter proteins (SLAP and SLAP-2) constitute a family of proteins that are expressed in a variety of cell types but are studied most extensively in lymphocytes. They have been shown to associate with proximal components of the T-cell recept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75132bada29d47ee7fd1565ccaaa372e
https://pubmed.ncbi.nlm.nih.gov/19909366
https://pubmed.ncbi.nlm.nih.gov/19909366
Autor:
Leonard L. Dragone, Margaret D. Myers, Hua Gu, Carmen White, Tomasz Sosinowski, Shyam Gadwal, Arthur Weiss
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 103(48)
Src-like adaptor protein (SLAP) and c-Cbl recently have been shown to cooperate in regulating T cell receptor (TCR) levels in developing T cells. SLAP also is expressed in developing B cells, and its deficiency leads to alterations in B cell receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45b61dbb2d62aa0fffcc56184a7e7d94
https://pubmed.ncbi.nlm.nih.gov/17110436
https://pubmed.ncbi.nlm.nih.gov/17110436
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 176(1)
The avidity of BCRs and TCRs influences signal strength during processes of lymphocyte development. Avidity is determined by both the intrinsic affinity for Ag and surface levels of the Ag receptor. The Src-like adaptor protein (SLAP) is a regulator
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f612e3c88f58dfeb4975fc2f6e09c30b
https://pubmed.ncbi.nlm.nih.gov/16365426
https://pubmed.ncbi.nlm.nih.gov/16365426
Publikováno v:
The Journal of Cell Biology
Src-like adaptor protein (SLAP) down-regulates expression of the T cell receptor (TCR)–CD3 complex during a specific stage of thymocyte development when the TCR repertoire is selected. Consequently, SLAP−/− thymocytes display alterations in thy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::821abfefc5b40b0859cd6341eae3cac9
https://pubmed.ncbi.nlm.nih.gov/16027224
https://pubmed.ncbi.nlm.nih.gov/16027224