Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Margaret Cui"'
Autor:
Stefan Radtke, Dnyanada Pande, Margaret Cui, Anai M. Perez, Yan-Yi Chan, Mark Enstrom, Stefanie Schmuck, Andrew Berger, Tom Eunson, Jennifer E. Adair, Hans-Peter Kiem
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 18, Iss , Pp 679-691 (2020)
Hematopoietic stem cell (HSC) gene therapy has the potential to cure many genetic, malignant, and infectious diseases. We have shown in a nonhuman primate gene therapy and transplantation model that the CD34+CD90+ cell fraction was exclusively respon
Externí odkaz:
https://doaj.org/article/261752fffa134004b8b8adfca84f2e43
Autor:
Rkia El-Kharrag, Kurt E. Berckmueller, Ravishankar Madhu, Margaret Cui, Gabriela Campoy, Heather M. Mack, Carl B. Wolf, Anai M. Perez, Olivier Humbert, Hans-Peter Kiem, Stefan Radtke
Publikováno v:
Mol Ther
Clinical applications of hematopoietic stem cell (HSC) gene editing are limited due to their complex and expensive logistics. HSC editing is commonly performed ex vivo using electroporation and requires good manufacturing practice (GMP) facilities, s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e005cc24577adbe147107518b4e2a261
https://doi.org/10.1016/j.ymthe.2022.02.026
https://doi.org/10.1016/j.ymthe.2022.02.026
Autor:
Stefan Radtke, Mark Enstrom, Dnyanada Pande, Ravishankar Madhu, Staci Owen, Greta Kanestrom, Margaret Cui, Anai M Perez, Hans-Peter Kiem
Publikováno v:
Blood. 140:5719-5720
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a07faaf8929f4f19ba15397400406a4d
https://doi.org/10.1182/blood-2022-158535
https://doi.org/10.1182/blood-2022-158535
Autor:
Margaret Cui, Andrew Berger, Stefanie Schmuck, Jennifer E. Adair, Anai M. Perez, Yan-Yi Chan, Tom Eunson, Hans-Peter Kiem, Stefan Radtke, Dnyanada Pande, Mark Enstrom
Publikováno v:
Molecular Therapy. Methods & Clinical Development
Molecular Therapy: Methods & Clinical Development, Vol 18, Iss, Pp 679-691 (2020)
Molecular Therapy: Methods & Clinical Development, Vol 18, Iss, Pp 679-691 (2020)
Hematopoietic stem cell (HSC) gene therapy has the potential to cure many genetic, malignant, and infectious diseases. We have shown in a nonhuman primate gene therapy and transplantation model that the CD34+CD90+ cell fraction was exclusively respon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::920b21f02a657c920794b84136a0fa70
http://europepmc.org/articles/PMC7424231
http://europepmc.org/articles/PMC7424231
Autor:
Mark Enstrom, Ravishankar Madhu, Stefan Radtke, Hans-Peter Kiem, Anai M. Perez, Margaret Cui, Dnyanada Pande
Reconstitution after hematopoietic stem cell (HSC) transplantation is assumed to occur in two distinct phases: initial recovery mediated by short-term progenitors and long-term repopulation by multipotent HSCs which do not contribute to hematopoietic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::962c6845b5571f8dc98cce5590d30e52
https://doi.org/10.1101/2021.09.21.461235
https://doi.org/10.1101/2021.09.21.461235
Autor:
Olivier Humbert, Ravishankar Madhu, Kurt Berckmueller, Stefan Radtke, Margaret Cui, Anai M. Perez, Hans-Peter Kiem, Rkia El Kharrag
Publikováno v:
Blood. 138:2933-2933
Autologous hematopoietic stem cell (HSC) gene therapy has the potential to cure millions of patients suffering from hematological diseases and disorders. Recent HSCs gene therapy trials using CRISPR/Cas9 nucleases to treat sickle cell disease (SCD) h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::26fc7ecb61c2e250bb026195c7f149c6
https://doi.org/10.1182/blood-2021-150924
https://doi.org/10.1182/blood-2021-150924
Autor:
Stefanie Schmuck, Jennifer E. Adair, Margaret Cui, Alice H. Berger, Stefan Radtke, Mark Enstrom, Anai M. Perez, Yan-Yi Chan, Tom Eunson, Hans-Peter Kiem, Dnyanada Pande
Hematopoietic stem cell (HSC) gene therapy has the potential to cure many genetic, malignant and infectious diseases. We have shown in a nonhuman primate (NHP) HSC gene therapy and transplantation model that the CD34+CD90+ cell fraction was exclusive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f11147e6dafc907e5f3bce554cdfad14
Autor:
Margaret Cui, Hans-Peter Kiem, Stefan Radtke, Clare Samuelson, Olivier Humbert, Anai M. Perez
Publikováno v:
Exp Hematol
AMD3100 (plerixafor) is a vital component of many clinical and pre-clinical transplant protocols, facilitating harvest of hematopoietic stem and progenitor cells through mobilization into the peripheral blood circulation. Repeat mobilization with AMD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9085305bb2212b92369e9fe710f46019
https://doi.org/10.1016/j.exphem.2020.11.001
https://doi.org/10.1016/j.exphem.2020.11.001