Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Margaret Coster"'
Autor:
Ewa Markiewicz, Stephen Barnard, Jackie Haines, Margaret Coster, Orry van Geel, Weiju Wu, Shane Richards, Elizabeth Ainsbury, Kai Rothkamm, Simon Bouffler, Roy A. Quinlan
Publikováno v:
Open Biology, Vol 5, Iss 4 (2015)
Elevated cataract risk after radiation exposure was established soon after the discovery of X-rays in 1895. Today, increased cataract incidence among medical imaging practitioners and after nuclear incidents has highlighted how little is still unders
Externí odkaz:
https://doaj.org/article/4e5211e9d0c04347bacf7982eda8c5a7
Autor:
Zenon Sienkiewicz, Penny A. Jeggo, Lara Barazzuol, Lisa Woodbine, Margaret Coster, Elizabeth A. Ainsbury, Jackie Haines
Publikováno v:
International Journal of Radiation Biology
International Journal of Radiation Biology, 91(6), 495-499
International Journal of Radiation Biology, 91(6), 495-499
Following in utero exposure to low dose radiation\ud (10 – 200 mGy), we recently observed a linear induction of DNA\ud double-strand breaks (DSB) and activation of apoptosis in the\ud embryonic neuronal stem/progenitor cell compartment. No\ud signi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b896970f9ceab09252ba6e5d784935ad
http://europepmc.org/articles/PMC4673581
http://europepmc.org/articles/PMC4673581
Autor:
Sylwia Kabacik, Masumi Abe, Kevin J. Whitehill, Claudine Raffy, Kevin M. Brindle, Margaret Coster, Simon Bouffler, Zenon Sienkiewicz, Christophe Badie, Heide L. Kirschenlohr
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. :40-45
To seek alterations in gene transcription in bone marrow cells following in vivo exposure of juvenile mice to power frequency magnetic fields, young (21–24-day old) C57BL/6 mice were exposed to a 100 μT 50 Hz magnetic field for 2 h. Transcription
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3aa6b2e33b2dc7398fc7488a6584a3a7
https://doi.org/10.1016/j.mrfmmm.2013.03.005
https://doi.org/10.1016/j.mrfmmm.2013.03.005
Autor:
Julie Adam, Simon Bouffler, Margaret Coster, Elizabeth A. Ainsbury, John Thacker, Jackie Haines, Michael Cheeseman
Publikováno v:
Molecular Cancer Research. 8:1227-1233
XRCC2 has an important role in repair of DNA damage by homologous recombination. Adult Apcmin/+ (min, multiple intestinal neoplasia) mice, wild-type or heterozygous for Xrcc2 deficiency, were sham-irradiated or 2-Gy X-irradiated. Spontaneous mammary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a71872fc1ac84338efc8cf26c2dc4ee7
https://doi.org/10.1158/1541-7786.mcr-10-0089
https://doi.org/10.1158/1541-7786.mcr-10-0089
The lens of the eye: exposures in the UK medical sector and mechanistic studies of radiation effects
Autor:
S Peters, P. J. Gilvin, Ewa Markiewicz, Stephen Barnard, Elizabeth A. Ainsbury, Simon Bouffler, Roy A. Quinlan, K Slack, Margaret Coster, J. Gillan, Kai Rothkamm
Publikováno v:
Annals of the ICRP. 44
The recommendation from the International Commission on Radiological Protection that the occupational equivalent dose limit for the lens of the eye should be reduced to 20 mSv year−1, averaged over 5 years with no year exceeding 50 mSv, has stimula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abde2c559660beec6467086f7b8af806
https://pubmed.ncbi.nlm.nih.gov/25816262
https://pubmed.ncbi.nlm.nih.gov/25816262
Autor:
Margaret Coster, M. Szłuińska, R. Finnon, Robert L. Ullrich, J.C. Moody, Christopher J. Skidmore, F. Darakhshan, Simon Bouffler, K. Yoshida, Alan Edwards, R. Cox, Christophe Badie, Paul Finnon
Publikováno v:
Carcinogenesis. 27:311-318
The mapping of genes which affect individual cancer risk is an important but complex challenge. A surrogate assay of susceptibility to radiation-induced acute myeloid leukaemia (AML) in the mouse based on chromosomal radiosensitivity has been develop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16957eb8164d729443a646badd424d73
https://doi.org/10.1093/carcin/bgi207
https://doi.org/10.1093/carcin/bgi207
Autor:
Margaret Coster, Erik Cabuy, Kevin Pack, Jackie Haines, Oliver M. Sieber, Victoria E. Johnson, Jennifer L. Wilding, Predrag Slijepcevic, Nirosha Suraweera, Mohammad Ilyas, Ian Tomlinson, Andrew Silver, Walter F. Bodmer
Publikováno v:
Proceedings of the National Academy of Sciences. 102:2868-2873
Apc Min mice have provided an example of a locus (Modifier of Min1 ; Mom1 ) modifying adenoma numbers in the intestines of inbred strains. Linkage analysis located Mom1 on chromosome 4, and further investigation identified secretory phospholipase A2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e027e8ce0d3f04cf9faa21aec0250aa9
https://doi.org/10.1073/pnas.0500039102
https://doi.org/10.1073/pnas.0500039102
Publikováno v:
DNA repair. 35
Female Apc(min/+) mice carrying the BALB/c variant of Prkdc or heterozygous knockout for Xrcc2, were sham- or 2 Gy X-irradiated as adults to compare the effect of mild impairments of double-strand break (DSB) repair pathways, non-homologous end joini
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8be7708c6b836511a7d8333e460e9586
https://pubmed.ncbi.nlm.nih.gov/26435054
https://pubmed.ncbi.nlm.nih.gov/26435054
Autor:
Shreya, Saha, Lisa, Woodbine, Jackie, Haines, Margaret, Coster, Nicole, Ricket, Lara, Barazzuol, Elizabeth, Ainsbury, Zenon, Sienkiewicz, Penny, Jeggo
Publikováno v:
Journal of the Royal Society Interface
The use of X-rays for medical diagnosis is enhancing exposure to low radiation doses. Exposure to extremely low-frequency electromagnetic or magnetic fields is also increasing. Epidemiological studies show consistent associations of childhood leukaem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f432878e8364c0bead7e306ea52dbcbc
https://pubmed.ncbi.nlm.nih.gov/25209403
https://pubmed.ncbi.nlm.nih.gov/25209403
Autor:
Margaret Coster, Jeffery W. Bacher, René Huiskamp, Mariateresa Mancuso, Emmy Meijne, Jackie Haines, Simon Bouffler, Simonetta Pazzaglia
Publikováno v:
International journal of radiation biology. 86(7)
Purpose: To investigate microsatellite instability (MSI) in radiation-induced murine tumours, its dependence on tissue (haemopoietic, intestinal, mammary, brain and skin) and radiation type. Materials and methods: DNA from spontaneous, X-ray or neutr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2638cc73816976d43d776dd854277c9d
https://pubmed.ncbi.nlm.nih.gov/20545567
https://pubmed.ncbi.nlm.nih.gov/20545567