Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Margaret C.L. Tse"'
Publikováno v:
Cellular Physiology and Biochemistry, Vol 50, Iss 4, Pp 1574-1584 (2018)
Background/Aims: Fibronectin type III domain-containing protein 5 (FNDC5), also known as irisin, is a myokine secreted from muscle in response to exercise. However, the molecular mechanisms that regulate FNDC5 expression and the functional significan
Externí odkaz:
https://doaj.org/article/e973227504af4ba28ca4a257c4902ff6
Publikováno v:
Molecular and Cellular Biology. 33:1797-1808
Fyn is a tyrosine kinase with multiple roles in a variety of cellular processes. Here we report that Fyn is a new kinase involved in adipocyte differentiation. Elevated Fyn protein is detected specifically in the adipocytes of obese mice. Moreover, F
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cddde8916aba36ef2ec950a7c95d6018
https://doi.org/10.1128/mcb.01410-12
https://doi.org/10.1128/mcb.01410-12
Publikováno v:
Gene. 412:26-38
Insulin-like growth factors (IGFs) belong to a family of growth factors with structural homology to proinsulin. Up till now, no specific details regarding the transcriptional regulation by autocrine, paracrine or endocrine effector molecules in vivo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f875df2e5ec19253362ab4189dba9ca5
https://doi.org/10.1016/j.gene.2007.12.023
https://doi.org/10.1016/j.gene.2007.12.023
Publikováno v:
General and Comparative Endocrinology. 155:729-741
Prolactin (PRL) is the most versatile hormone identified with multiple functions from osmoregulation in euryhaline fish to lactation in mammals. However, little is known about the basic physiological control of PRL in stenohaline freshwater fish. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c39cb4c3deb751a7a6c0e9ef8b781cbc
https://doi.org/10.1016/j.ygcen.2007.08.008
https://doi.org/10.1016/j.ygcen.2007.08.008
Autor:
Keqiang Ye, Reed Otten, Shuai Zhang, Margaret C.L. Tse, Xia Liu, Robin H Schmidt, Liegang Liu, Chi Bun Chan
SummaryChronic activation of brain-derived neurotrophic factor (BDNF) receptor TrkB is a potential method to prevent development of obesity, but the short half-life and nonbioavailable nature of BDNF hampers validation of the hypothesis. We report he
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da7fe056fefa125173be57be90912eb8
https://europepmc.org/articles/PMC4369457/
https://europepmc.org/articles/PMC4369457/
Publikováno v:
The Journal of Neuroscience. 26:3299-3308
Human astrocytes express Fas yet are resistant to Fas-induced apoptosis. Here, we report that calcium/calmodulin-dependent protein kinase II (CaMKII) is constitutively activated in human astrocytes and protects the cells from apoptotic stimulation by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ede120f6d0e59d12bb8c2b0817697240
https://doi.org/10.1523/jneurosci.5572-05.2006
https://doi.org/10.1523/jneurosci.5572-05.2006
Autor:
Jeffrey J. Olson, Margaret C.L. Tse, Shi-Yong Sun, Jin H. Song, Chunhai Hao, Anita C. Bellail, Surasak Phuphanich
Publikováno v:
Journal of Cellular and Molecular Medicine
To explore the molecular mechanisms by which glioblastomas are resistant to tumour necrosis factor-related apoptosis-inducing ligand (TRAIL), we examined TRAIL signalling pathways in the tumours. TRAIL has four membrane-anchored receptors, death rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e153ac950e9249802c2d39f2ea793a79
https://pubmed.ncbi.nlm.nih.gov/19432816
https://pubmed.ncbi.nlm.nih.gov/19432816
Autor:
Kevin R. Mott, Hui Mien Hsiao, Nattawat Onlamoon, Guey Chuen Perng, Margaret C.L. Tse, Crystal Lane
Publikováno v:
Journal of neuroimmunology. 213(1-2)
Chemokines are important in HSE development in the CNS but underlying regulatory events are unknown. Two-hybrid binding assays identified that intercellular adhesion molecule 5 (ICAM-5), an immune modulator in the CNS, interacted with neurovirulence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18db208b726d1a2370f7aeb292988a00
https://pubmed.ncbi.nlm.nih.gov/19589604
https://pubmed.ncbi.nlm.nih.gov/19589604
Autor:
Anita C. Bellail, Surasak Phuphanich, Jin H. Song, Fadlo R. Khuri, Margaret C.L. Tse, Norman M. Kneteman, Chunhai Hao
Publikováno v:
Cancer research. 67(14)
Tumor necrosis factor–related apoptosis-inducing ligand (TRAIL) is capable of inducing apoptosis in non–small cell lung carcinoma (NSCLC). However, many of the human NSCLC cell lines are resistant to TRAIL, and TRAIL treatment of the resistant ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fa82c3d1496e22017c653329d479ce6
https://pubmed.ncbi.nlm.nih.gov/17638906
https://pubmed.ncbi.nlm.nih.gov/17638906
Publikováno v:
The FASEB Journal. 21
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d31fb265e401438448ee0afe65b0b5a2
https://doi.org/10.1096/fasebj.21.5.a31-b
https://doi.org/10.1096/fasebj.21.5.a31-b