Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Margaret C. Minkwitz"'
Autor:
Phillip E. Korenblat, Margaret C. Minkwitz, James P. Kemp, William Mezzanotte, Joseph E. Scherger
Publikováno v:
Annals of Allergy, Asthma & Immunology. 84:217-225
Background The Accolate Clinical Experience and Pharmacoepidemiology Trial (ACCEPT), evaluated zafirlukast in a wide spectrum of patients from a variety of clinical practices. Objective To determine the effect of age on the response to zafirlukast 20
Publikováno v:
Chest. 115:336-342
We evaluated the efficacy of the leukotriene receptor antagonist zafirlukast (Accolate), 20 mg twice daily, as monotherapy in patients with severe persistent asthma (defined by an FEV160% of predicted before treatment and frequent night-time symptoms
Autor:
Michael J. Watts, Stephen C. Lazarus, Hofer Wong, Margaret C. Minkwitz, Bernard J. Lavins, Homer A. Boushey
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 156:1725-1730
Inhalation of sulfur dioxide (SO2) causes bronchoconstriction in most people with asthma. To examine the role of leukotrienes in this response, the antagonism of SO2-induced bronchoconstriction by a single oral dose of the leukotriene receptor antago
Publikováno v:
Annals of allergy, asthmaimmunology : official publication of the American College of Allergy, Asthma,Immunology. 82(5)
New drug evaluations in patients with mild asthma are sometimes complicated by enrollment of patients whose disease is too mild to show improvement with therapy. A peak expiratory flow (PEF) variability criterion may help to more clearly define a mil
Autor:
Catherine M. Bonuccelli, Robert A. Nathan, Steven G. Simonson, Donald P. Tashkin, William C. Howland, Margaret C. Minkwitz
Publikováno v:
The Journal of allergy and clinical immunology. 103(2 Pt 1)
Consensus asthma guidelines recommend antileukotriene agents as alternative therapy to existing anti-inflammatory medications; however, the full therapeutic potential of these medications has not yet been determined.The purpose of this study was to a
Autor:
Robert L. Wortmann, Ralph H. Schumacher, William A. Palo, Nancy Joseph-Ridge, Michael A. Becker, Patricia A. McDonald, Daniel Flores, Roderick J. Halbert, Jeannine Guenther, Kate Zhong, Pierre N. Tarcot, Margaret C. Minkwitz, Nancy A. Devine, Jacobo Mintzer
Publikováno v:
The Consultant Pharmacist. 21:76-77
Publikováno v:
Chest. 105(2)
Three inhalation formulations of ICI 204,219 were compared for antagonism of antigen-induced bronchoconstriction in 16 subjects with asthma who demonstrated reproducible hypersensitivity to allergen during screening challenges. Each subject received
Publikováno v:
Clinical pharmacology and therapeutics. 54(4)
The peptide-leukotriene antagonist, ICI 204,219 [4-(5-cyclopentyloxycarbonylamino-lmethylindol-3-ylmethyl)-3-methoxy-n-o-tolylsulfonyl benzamide], was administered 12 hours before an inhaled leukotriene D4 (LTD4) challenge during a double-blind, plac