Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Margaret C. Eggo"'
Autor:
Christopher J. McCabe, Kristien Boelaert, Jayne A. Franklyn, John C. Watkinson, Wendy E. Leadbeater, Jeffrey A. Knauf, Margaret C. Eggo, Adrian Warfield, Erica Gentilin, Vicki E. Smith, Robert I. Seed, Neil Sharma, Jim C.W. Fong, Greg D. Lewy, Martin L. Read
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Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::135cefef3a1dba892a6fbb1f007ac725
https://doi.org/10.1158/0008-5472.22391399.v1
https://doi.org/10.1158/0008-5472.22391399.v1
Autor:
Christopher J. McCabe, Kristien Boelaert, Jayne A. Franklyn, John C. Watkinson, Wendy E. Leadbeater, Jeffrey A. Knauf, Margaret C. Eggo, Adrian Warfield, Erica Gentilin, Vicki E. Smith, Robert I. Seed, Neil Sharma, Jim C.W. Fong, Greg D. Lewy, Martin L. Read
Pituitary tumor transforming gene (PTTG)-binding factor (PBF or PTTG1IP) is a little characterized proto-oncogene that has been implicated in the etiology of breast and thyroid tumors. In this study, we created a murine transgenic model to target PBF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::42353d8d2975333dc5409ddcf1604ee9
https://doi.org/10.1158/0008-5472.c.6503249.v1
https://doi.org/10.1158/0008-5472.c.6503249.v1
Publikováno v:
Journal of Cellular Physiology. 227:1992-2002
Human thyroid follicular cells in culture expressed the mRNAs for the receptors for vascular endothelial growth factors (VEGFRs). The relative expression was neuropilin1 = neuropilin2 = VEGFR2 > VEGFR1 > VEGFR3. Western blotting for VEGFR2 showed lab
Publikováno v:
Experimental Neurology. 233:154-162
The role of taurine in regulating glucose-induced nitrosative stress has been examined in human Schwann cells, a model for understanding the pathogenesis of diabetic neuropathy. Exposure to high glucose increased nitrated proteins (1.56 fold p
Autor:
Margaret C. Eggo
Publikováno v:
Current Opinion in Endocrinology, Diabetes and Obesity. 17:396-401
Purpose of review For de-novo thyroid hormone synthesis ex vivo, thyroid follicular cells require a serum-free medium supplying nutrients, iodide, thyroid-stimulating hormone and insulin-like growth factor I (IGF-I) (or insulin). Under these conditio
Autor:
Margaret C. Eggo, Martin L. Read, Moray J. Campbell, Jayne A. Franklyn, Gary M. Reynolds, Christopher McCabe, Neil Sharma, Laura Buckley, Greg Lewy, Vicki Smith, Kristien Boelaert, Laurence Loubiere, Craig L. Doig, Rachel Watkins
Publikováno v:
Cancer Research. 70:3739-3749
Pituitary tumor transforming gene (PTTG) binding factor (PBF; PTTG1IP) is a relatively uncharacterized oncoprotein whose function remains obscure. Because of the presence of putative estrogen response elements (ERE) in its promoter, we assessed PBF r
Autor:
John Watkinson, Kristien Boelaert, Martin L. Read, Margaret C. Eggo, Sally R. James, Andrew S. Turnell, Christopher McCabe, Vicki Smith, Jayne A. Franklyn, Jim Fong, Gregory Lewy, Rachel Watkins
Publikováno v:
Journal of Cell Science. 122:3393-3402
Differentiated thyroid cancers and their metastases frequently exhibit reduced iodide uptake, impacting on the efficacy of radioiodine ablation therapy. PTTG binding factor (PBF) is a proto-oncogene implicated in the pathogenesis of thyroid cancer. W
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 297:E620-E628
In human Schwann cells, the role of taurine in regulating glucose-induced changes in antioxidant defense systems has been examined. Treatment with high glucose for 7 days induced reactive oxygen species, increased 4-hydroxynoneal adducts (20 ± 5%, P
Publikováno v:
British Journal of Surgery. 95:281-293
Background Antiangiogenic therapy has become a reality with the recent introduction of bevacizumab, a monoclonal antibody against vascular endothelial growth factor. Methods Relevant medical literature from PubMed, National Institute for Health and C
Publikováno v:
Digestive Diseases and Sciences. 52:373-378
Impaired butyrate oxidation and raised counts of sulfate-reducing bacteria in the colon of patients with ulcerative colitis (UC) indicate that the disease may be induced or aggravated by hydrogen sulfide toxicity. We aimed to examine enzymatic remova