Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Margaret C. Carpenter"'
Autor:
Shiwei Xu, Margaret C. Carpenter, Rachel L. Spreng, Scott D. Neidich, Sharanya Sarkar, DeAnna Tenney, Derrick Goodman, Sheetal Sawant, Shalini Jha, Brooke Dunn, M. Juliana McElrath, Valerie Bekker, Sarah V. Mudrak, Robin Flinko, George K. Lewis, Guido Ferrari, Georgia D. Tomaras, Xiaoying Shen, Margaret E. Ackerman
Publikováno v:
npj Vaccines, Vol 7, Iss 1, Pp 1-14 (2022)
Abstract Adjuvants can alter the magnitude, characteristics, and persistence of the humoral response to protein vaccination. HIV vaccination might benefit from tailored adjuvant choice as raising a durable and protective response to vaccination has b
Externí odkaz:
https://doaj.org/article/9ea7f299da3f47918d880c37d8b44de9
Publikováno v:
Curr Opin HIV AIDS
Purpose of review Recent work defining Fc-mediated effector functions for both viral control and protection against infection is summarized and considered along with new strategies to drive robust Fc-mediated responses. Recent findings In new human a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::793ab1a7c1553abf8eea1766fd901038
https://doi.org/10.1097/coh.0000000000000638
https://doi.org/10.1097/coh.0000000000000638
Intracellular Zn2+ transients modulate global gene expression in dissociated rat hippocampal neurons
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-14 (2019)
Zinc (Zn2+) is an integral component of many proteins and has been shown to act in a regulatory capacity in different mammalian systems, including as a neurotransmitter in neurons throughout the brain. While Zn2+ plays an important role in modulating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57274d64b5e326efa79d5d3e1810a805
http://link.springer.com/article/10.1038/s41598-019-45844-2
http://link.springer.com/article/10.1038/s41598-019-45844-2
Autor:
Sherry Stanfield-Oakley, Wes Rountree, Guido Ferrari, George M. Shaw, Margaret E. Ackerman, Christopher A.L. Remmel, Steven G. Reed, Georgia D. Tomaras, Yunfei Wang, Zhongyan Lu, Barton F. Haynes, Nathan Vandergrift, Faith Schiro, Galit Alter, Margherita Rosati, Hung V. Trinh, Celia C. LaBranche, Katelyn Faircloth, Mangala Rao, Xiaoying Shen, Ronald S. Veazey, Wilton B. Williams, Munir Alam, David Venzon, Xintao Hu, Kevin O. Saunders, Bapi Pahar, George N. Pavlakis, Jason Dufour, Preston A. Marx, Pyone P. Aye, Joshua A. Weiner, Jishnu Das, Antonio Valentin, Margaret C. Carpenter, Barbara K. Felber, David C. Montefiori
Publikováno v:
Cell Rep
Summary We compare immunogenicity and protective efficacy of an HIV vaccine comprised of env and gag DNA and Env (Envelope) proteins by co-administration of the vaccine components in the same muscles or by separate administration of DNA + protein in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4790df4efa90b525ae6011971373d20
https://europepmc.org/articles/PMC7329227/
https://europepmc.org/articles/PMC7329227/
Publikováno v:
Analytical Chemistry. 89:9601-9608
Genetically-encoded sensors based on fluorescence resonance energy transfer (FRET) are powerful tools for quantifying and visualizing analytes in living cells, and when targeted to organelles have the potential to define distribution of analytes in d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c4f23085f06227f75f0ab9fc4b55b4e
https://doi.org/10.1021/acs.analchem.7b02933
https://doi.org/10.1021/acs.analchem.7b02933
Autor:
David L. Ollis, Dean E. Wilcox, Nataša Mitić, Gerhard Schenk, Margaret C. Carpenter, Lawrence R. Gahan, Marcelo Monteiro Pedroso, Fernanda Ely
Publikováno v:
Biochemistry. 56:3328-3336
Glycerophosphodiesterase (GpdQ) from Enterobacter aerogenes is a binuclear metallohydrolase with a high affinity for metal ions at its α site but a lower affinity at its β site in the absence of a substrate. Isothermal titration calorimetry (ITC) h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56802c34bffdd8a565de0597b2948da5
https://doi.org/10.1021/acs.biochem.6b01200
https://doi.org/10.1021/acs.biochem.6b01200
Autor:
Amy E. Palmer, Margaret C. Carpenter
Publikováno v:
Essays in Biochemistry. 61:237-243
Ca2+ and Zn2+ dynamics have been identified as important drivers of physiological processes. In order for these dynamics to encode function, the cell must have sensors that transduce changes in metal concentration to specific downstream actions. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::901f1cd5949a1eb6ddba2e86a30f7ee9
https://doi.org/10.1042/ebc20160069
https://doi.org/10.1042/ebc20160069
Autor:
Steven Van Buskirk, Brett L. Fiedler, Kyle P. Carter, Ralph Jimenez, Margaret C. Carpenter, Yan Qin, Amy E. Palmer
Publikováno v:
Analytical Chemistry. 89:711-719
Fluorescent biosensors are important measurement tools for in vivo quantification of pH, concentrations of metal ions and other analytes, and physical parameters such as membrane potential. Both the development of these sensors and their implementati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db993dba013a81d0ce51a6ebf1c2b6af
https://doi.org/10.1021/acs.analchem.6b03235
https://doi.org/10.1021/acs.analchem.6b03235
Publikováno v:
Scientific Reports
Zinc (Zn2+) is an integral component of many proteins and has been shown to act in a regulatory capacity in different mammalian systems, including as a neurotransmitter in neurons throughout the brain. While Zn2+ plays an important role in modulating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::faa9c201061be10ae0e465152b077bfe
https://pubmed.ncbi.nlm.nih.gov/31253848
https://pubmed.ncbi.nlm.nih.gov/31253848
Publikováno v:
ACS Chemical Biology. 11:2744-2751
Various fluorescent probes have been developed to reveal the biological functions of intracellular labile Zn2+. Here, we present Green Zinc Probe (GZnP), a novel genetically encoded Zn2+ sensor design based on a single fluorescent protein (single-FP)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f25ee87f44d173bba782cc324c9ae8b6
https://doi.org/10.1021/acschembio.6b00442
https://doi.org/10.1021/acschembio.6b00442