Výsledky vyhledávání - "Margaret Barkett"

Biological characterization of Drosophila Rapgap1, a GTPase activating protein for Rap1

Autor: Fangli Chen, Adrian Quintanilla, Margaret Barkett, Kavitha T. Ram, Iswar K. Hariharan

Publikováno v: Proceedings of the National Academy of Sciences. 94:12485-12490

The activity of Ras family proteins is modulated in vivo by the function of GTPase activating proteins, which increase their intrinsic rate of GTP hydrolysis. We have isolated cDNAs encoding a GAP for the Drosophila Rap1 GTPase. Drosophila Rapgap1 en

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::255019e90dab31ac5a9d431e7969b06d
https://doi.org/10.1073/pnas.94.23.12485

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Hematopoietic growth factor receptor genes as markers of lineage commitment during in vitro development of hematopoietic cells [see comments]

Autor: Stacie A. Dalrymple, Terrill McClanahan, Frank X. Lee, Margaret Barkett

Publikováno v: Blood. 81:2903-2915

We have used two in vitro models to identify genes whose expression may serve as markers of lineage commitment during the development of hematopoietic stem cells. One system involves the development in vitro of blastocyst-derived embryonic stem cells

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ba830af40941201d9c2a26dc838b01b
https://doi.org/10.1182/blood.v81.11.2903.bloodjournal81112903

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Three mutations in v-Rel render it resistant to cleavage by cell-death protease caspase-3

Autor: Lori Lemonnier, Julia E. Dooher, Thomas D. Gilmore, Yuan Wang, Margaret Barkett, Jennifer N. Scarpati, La Vone Simmons

Publikováno v: Biochimica et biophysica acta. 1526(1)

The retroviral oncoprotein v-Rel is a transcriptional activator in the Rel/NF-kappa B family. v-Rel causes rapidly fatal lymphomas in young chickens, and transforms and immortalizes chicken lymphoid cells in vitro. Several mutations that have enhance

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6df9ddb2e857979df03a8a65abc3c648
https://pubmed.ncbi.nlm.nih.gov/11287119

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Control of apoptosis by Rel/NF-kappaB transcription factors

Autor: Thomas D. Gilmore, Margaret Barkett

Publikováno v: Oncogene. 18(49)

Apoptosis is a physiological process critical for organ development, tissue homeostasis, and elimination of defective or potentially dangerous cells in complex organisms. Apoptosis can be initiated by a wide variety of stimuli, which activate a cell

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c051808e20ecb7ee7e9af5e0065b5efe
https://pubmed.ncbi.nlm.nih.gov/10602466

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