Zobrazeno 1 - 10
of 85
pro vyhledávání: '"Margaret Ashton"'
Autor:
Amatta Mirandari, Helen Parker, Margaret Ashton-Key, Benjamin Stevens, Renata Walewska, Kostas Stamatopoulos, Dean Bryant, David G. Oscier, Jane Gibson, Jonathan C. Strefford
Publikováno v:
Exploration of Targeted Anti-tumor Therapy, Vol 5, Iss 4, Pp 877-901 (2024)
Splenic marginal zone lymphoma (SMZL) is a rare, predominantly indolent B-cell lymphoma constituting fewer than 2% of lymphoid neoplasms. However, around 30% of patients have a shorter survival despite currently available treatments and the prognosis
Externí odkaz:
https://doaj.org/article/ad841940a5e44526b382eb52d66bee83
Autor:
Elizabeth J. Soilleux, Daniel T. Rodgers, Jinlong J. Situ, Shelley C. Evans, Venkata N. Konda, Han-Chieh Yang, Jianxiong Pang, Isabella Gilbey Smith, Pete Rajesh, Maryam Salimi, Soo Weei Ng, Julia Jones, Jodi L. Miller, Rachel Etherington, Margaret Ashton-Key, Graham Ogg
Publikováno v:
Diagnostics, Vol 14, Iss 22, p 2479 (2024)
Background/Objectives: T-cell lymphomas are often histologically indistinguishable from benign T-cell infiltrates, and diagnosis typically relies on slow, complex, and expensive multiplexed PCR reactions, requiring significant training and experience
Externí odkaz:
https://doaj.org/article/e6a2c6b212a24342a8501376bc0f3ffe
Autor:
Charles N. Birts, Constantinos Savva, Stéphanie A. Laversin, Alicia Lefas, Jamie Krishnan, Aron Schapira, Margaret Ashton-Key, Max Crispin, Peter W. M. Johnson, Jeremy P. Blaydes, Ellen Copson, Ramsey I. Cutress, Stephen A. Beers
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Obesity can initiate, promote, and maintain systemic inflammation via metabolic reprogramming of macrophages that encircle adipocytes, termed crown-like structures (CLS). In breast cancer the presence of CLS has been correlated to high body
Externí odkaz:
https://doaj.org/article/da0c57731b534a49b7c1cad924db34c5
Autor:
Emily R. Webb, Silvia Lanati, Carol Wareham, Alistair Easton, Stuart N. Dunn, Tatyana Inzhelevskaya, Freja M. Sadler, Sonya James, Margaret Ashton-Key, Mark S. Cragg, Stephen A. Beers, Juliet C. Gray
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-17 (2020)
Abstract Immunotherapy offers a potentially less toxic, more tumor-specific treatment for neuroblastoma than conventional cytotoxic therapies. Accurate and reproducible immune competent preclinical models are key to understanding mechanisms of action
Externí odkaz:
https://doaj.org/article/1cd179c8bd0e4a0ba1a1db6fa9ea0186
Autor:
Russell Foxall, Priyanka Narang, Bridget Glaysher, Elin Hub, Emma Teal, Mark C. Coles, Margaret Ashton-Key, Stephen A. Beers, Mark S. Cragg
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
Diffuse large cell B cell lymphoma (DLBCL) accounts for approximately 30%–40% of all non-Hodgkin lymphoma (NHL) cases. Current first line DLBCL treatment results in long-term remission in more than 60% of cases. However, those patients with primary
Externí odkaz:
https://doaj.org/article/f7e066eab461442e986826c1d67e4590
Autor:
Carla Fuster, David Martín-Garcia, Olga Balagué, Alba Navarro, Ferran Nadeu, Dolors Costa, Miriam Prieto, Itziar Salaverria, Blanca Espinet, Alfredo Rivas-Delgado, Maria José Terol, Eva Giné, Pilar Forcada, Margaret Ashton-Key, Xose S. Puente, Steven H. Swerdlow, Sílvia Beà, Elias Campo
Publikováno v:
Haematologica, Vol 105, Iss 8 (2020)
Externí odkaz:
https://doaj.org/article/36418909a9c442de849c902edba59109
Autor:
Shamzah Araf, Jun Wang, Margaret Ashton-Key, Koorosh Korfi, Doriana Di Bella, Ana Rio-Machin, Mariette Odabashian, Vipul Foria, Ming-Qing Du, Francesco Cucco, Sharon Barrans, Peter Johnson, Sophie R. Laird, Andrew M. Fisher, Jonathan O. Cullis, Trevor A. Graham, Jessica Okosun, Jude Fitzgibbon, Laura Chiecchio
Publikováno v:
Haematologica, Vol 104, Iss 4 (2019)
Externí odkaz:
https://doaj.org/article/9c978eeedf684e758ab8e3dfc16c178b
Autor:
Sarah Moody, Joe Sneath Thompson, Shih-Sung Chuang, Hongxiang Liu, Markus Raderer, George Vassiliou, Iwona Wlodarska, Fangtian Wu, Sergio Cogliatti, Alistair Robson, Margaret Ashton-Key, Yingwen Bi, John Goodlad, Ming-Qing Du
Publikováno v:
Haematologica, Vol 103, Iss 8 (2018)
Mucosa-associated lymphoid tissue (MALT) lymphoma originates from a background of diverse chronic inflammatory disorders at various anatomic sites. The genetics underlying its development, particularly in those associated with autoimmune disorders, i
Externí odkaz:
https://doaj.org/article/229a2f1ed1f34b63a5623d7458eb845e
Autor:
Findlay Bewicke-Copley, Koorosh Korfi, Shamzah Araf, Brendan Hodkinson, Emil Kumar, Thomas Cummin, Margaret Ashton-Key, Sharon Barrans, Suzan van Hoppe, Cathy Burton, Mohamed Elshiekh, Simon Rule, Nicola Crosbie, Andrew Clear, Maria Calaminici, Hendrik Runge, Robert K. Hills, David W. Scott, Lisa M. Rimsza, Geetha Menon, Chulin Sha, John R. Davies, Ai Nagano, Andrew Davies, Daniel Painter, Alexandra Smith, John Gribben, Kikkeri N. Naresh, David R. Westhead, Jessica Okosun, Andrew Steele, Daniel J. Hodson, Sriram Balasubramanian, Peter Johnson, Jun Wang, Jude Fitzgibbon
Publikováno v:
Blood Advances. 7:845-855
Despite the effectiveness of immuno-chemotherapy, 40% of patients with diffuse large B-cell lymphoma (DLBCL) experience relapse or refractory disease. Longitudinal studies have previously focused on the mutational landscape of relapse but fell short