Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Margaret A. Scull"'
Autor:
Niayesh Razi, Weizhong Li, Maxinne A. Ignacio, Jeffrey M. Loube, Eva L. Agostino, Xiaoping Zhu, Margaret A. Scull, Jeffrey J. DeStefano
Publikováno v:
Respiratory Research, Vol 24, Iss 1, Pp 1-11 (2023)
Abstract Background SARS-CoV-2, the agent responsible for the COVID-19 pandemic, enters cells through viral spike glycoprotein binding to the cellular receptor, angiotensin-converting enzyme 2 (ACE2). Given the lack of effective antivirals targeting
Externí odkaz:
https://doaj.org/article/b7423d2e95a8442f8391cf82c24054b9
Autor:
Monty E. Goldstein, Maxinne A. Ignacio, Jeffrey M. Loube, Matthew R. Whorton, Margaret A. Scull
Publikováno v:
Viruses, Vol 16, Iss 8, p 1282 (2024)
Rhinovirus C (RV-C) infects airway epithelial cells and is an important cause of acute respiratory disease in humans. To interrogate the mechanisms of RV-C-mediated disease, animal models are essential. Towards this, RV-C infection was recently repor
Externí odkaz:
https://doaj.org/article/03cfa3f44b634fafa597432eba8ed483
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-9 (2022)
Influenza A virus movement in mucus is found to be affected by the mesh structure of the gel network and further analysis reveals weak IAV-mucus binding.
Externí odkaz:
https://doaj.org/article/fc1f231787794dae902950d4855d062c
Autor:
Ethan Iverson, Kira Griswold, Daniel Song, Talita B. Gagliardi, Kajal Hamidzadeh, Mehmet Kesimer, Sanju Sinha, Melissa Perry, Gregg A. Duncan, Margaret A. Scull
Publikováno v:
mBio, Vol 13, Iss 4 (2022)
ABSTRACT Influenza A virus (IAV) causes significant morbidity and mortality in the human population. Tethered mucin 1 (MUC1) is highly expressed in airway epithelium, the primary site of IAV replication, and also by other cell types that influence IA
Externí odkaz:
https://doaj.org/article/28f23bc5faf040c18f6238af702af84f
Autor:
Ursula Andreo, Ype P. de Jong, Margaret A. Scull, Jing W. Xiao, Koen Vercauteren, Corrine Quirk, Michiel C. Mommersteeg, Sonia Bergaya, Arjun Menon, Edward A. Fisher, Charles M. Rice
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 4, Iss 3, Pp 405-417 (2017)
Background & Aims: Hepatitis C virus (HCV) is a leading cause of chronic liver diseases and the most common indication for liver transplantation in the United States. HCV particles in the blood of infected patients are characterized by heterogeneous
Externí odkaz:
https://doaj.org/article/f81b24bdf4364b179d790a21b3bc8ca6
Autor:
Constantin N. Takacs, Ursula Andreo, Viet Loan Dao Thi, Xianfang Wu, Caroline E. Gleason, Michelle S. Itano, Gabriella S. Spitz-Becker, Rachel L. Belote, Brenna R. Hedin, Margaret A. Scull, Charles M. Rice, Sanford M. Simon
Publikováno v:
Cell Reports, Vol 21, Iss 2, Pp 431-441 (2017)
Summary: Secretory cells produce diverse cargoes, yet how they regulate concomitant secretory traffic remains insufficiently explored. Rab GTPases control intracellular vesicular transport. To map secretion pathways, we generated a library of lentivi
Externí odkaz:
https://doaj.org/article/fa22d4a9059a426fa651430a48004744
Publikováno v:
Viruses, Vol 12, Iss 12, p 1425 (2020)
Respiratory viruses remain a significant cause of morbidity and mortality in the human population, underscoring the importance of ongoing basic research into virus–host interactions. However, many critical aspects of infection are difficult, if not
Externí odkaz:
https://doaj.org/article/edfc9341a2704fe5a30f45a02f28f200
Autor:
Margaret M. Scull
Publikováno v:
Journal of Religious History. 46:281-302
Publikováno v:
Science Advances. 8
Secreted mucus is a frontline defense against respiratory infection, enabling the capture and swift removal of infectious or irritating agents from the lungs. Airway mucus is composed of two mucins: mucin 5B (MUC5B) and 5AC (MUC5AC). Together, they f
Autor:
Margaret M. Scull, Niall Gilmartin
Publikováno v:
Women's History Review. 31:721-740
Although the practice of strip searching of female prisoners in Northern Ireland was used in the1970s, it reached its height in Armagh Jail between 1980 and 1986. Based on in-depth interviews and e...