Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Margaret A. Gustafson"'
Autor:
Margaret A Gustafson, Elizabeth M McCormick, Lalith Perera, Matthew J Longley, Renkui Bai, Jianping Kong, Matthew Dulik, Lishuang Shen, Amy C Goldstein, Shana E McCormack, Benjamin L Laskin, Bart P Leroy, Xilma R Ortiz-Gonzalez, Meredith G Ellington, William C Copeland, Marni J Falk
Publikováno v:
PLoS ONE, Vol 14, Iss 9, p e0221829 (2019)
Mitochondrial DNA (mtDNA) genome integrity is essential for proper mitochondrial respiratory chain function to generate cellular energy. Nuclear genes encode several proteins that function at the mtDNA replication fork, including mitochondrial single
Externí odkaz:
https://doaj.org/article/63b1a4fb63464668996acd615bcb408a
Publikováno v:
eLife, Vol 5 (2016)
Externí odkaz:
https://doaj.org/article/68dcb1b595d74425b305c46f4c848e81
Publikováno v:
eLife, Vol 5 (2016)
The Golgi complex is the central sorting compartment of eukaryotic cells. Arf guanine nucleotide exchange factors (Arf-GEFs) regulate virtually all traffic through the Golgi by activating Arf GTPase trafficking pathways. The Golgi Arf-GEFs contain mu
Externí odkaz:
https://doaj.org/article/6af0cd482bc6469ba8f78c3e69fa72c7
Publikováno v:
Cell Reports. 40:111282
The Golgi complex is the central sorting station of the eukaryotic secretory pathway. Traffic through the Golgi requires activation of Arf guanosine triphosphatases that orchestrate cargo sorting and vesicle formation by recruiting an array of effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40065ed72187a4fcc95958b66f4477b5
https://doi.org/10.1016/j.celrep.2022.111282
https://doi.org/10.1016/j.celrep.2022.111282
Publikováno v:
DNA Repair (Amst)
Several mutations in the gene for the mitochondrial single stranded DNA binding protein (SSBP1) have recently been implicated in human disease, but initial reports are insufficient to explain the molecular mechanism of disease, including the possible
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4486221b386cadf4006408b8804a8a97
https://pubmed.ncbi.nlm.nih.gov/34464898
https://pubmed.ncbi.nlm.nih.gov/34464898
Autor:
Holger Prokisch, Evan H. Baugh, Valentina Del Dotto, Michele Carbonelli, Rocco Liguori, Mirjana Gusic, Wolfgang Sperl, Tommaso Pippucci, Nicholas Stong, Pamela Magini, Enrico Bertini, William C. Copeland, Alessandra Maresca, Francesca Diomedi-Camassei, Shashi K. Nagaraj, Ioana Cutcutache, Bertil Macao, Alessandro Iannaccone, Francesco Emma, Piero Barboni, Marco Seri, Vandana Shashi, Zsolt Szilagyi, Farid Ullah, Camille Peron, Valerio Carelli, Chiara La Morgia, Ivano Di Meo, Martin Armstrong, Jennifer A. Sullivan, Saskia B. Wortmann, Nicholas Katsanis, Leonardo Caporali, Kamal Khan, Maria Falkenberg, Valeria Tiranti, Mays A. El-Dairi, Erica E. Davis, Maria Lucia Valentino, Margaret A. Gustafson, Claudia Zanna, Rosalba Carrozzo, Sylvia Boesch, Flavia Palombo, Francesca Tagliavini, Robert Kopajtich, Matthew Page
Publikováno v:
J. Clin. Invest. 130, 108-125 (2020)
Inherited optic neuropathies include complex phenotypes, mostly driven by mitochondrial dysfunction. We report an optic atrophy spectrum disorder, including retinal macular dystrophy and kidney insufficiency leading to transplantation, associated wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f59384a409cfa55c80cfd8e64162ba11
https://europepmc.org/articles/PMC6934201/
https://europepmc.org/articles/PMC6934201/
Publikováno v:
The FASEB Journal. 33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2618fa2dd7bc9966314118585b702115
https://doi.org/10.1096/fasebj.2019.33.1_supplement.657.2
https://doi.org/10.1096/fasebj.2019.33.1_supplement.657.2
Publikováno v:
Molecular Biology of the Cell
The Rab GTPase Ypt1 recruits the Golgi Arf-GEFs Gea1, Gea2, and Sec7 to distinct parts of the Golgi. Early Golgi localized Gea1 and Gea2 prefer neutral membranes, whereas late Golgi localized Sec7 prefers anionic membranes. The C-terminal domains of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a33f31a8fef2e41379aa8cdbe12da00
http://europepmc.org/articles/PMC5706993
http://europepmc.org/articles/PMC5706993
Publikováno v:
DNA Repair (Amst)
Maintenance and replication of the mitochondrial genome (mtDNA) is essential to mitochondrial function and eukaryotic energy production through the electron transport chain. mtDNA is replicated by a core set of proteins: Pol γ, Twinkle, and the sing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc2e3ed25638115944f5184537959337
https://doi.org/10.1016/j.dnarep.2020.102916
https://doi.org/10.1016/j.dnarep.2020.102916
Publikováno v:
Journal of Biological Chemistry. 287:9222-9229
Cyclobutane thymine dimers (T-T) comprise the majority of DNA damage caused by short wavelength ultraviolet radiation. These lesions generally block replicative DNA polymerases and are repaired by nucleotide excision repair or bypassed by translesion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::280f9f8a6ffaa886261c604b737d4708
https://doi.org/10.1074/jbc.m111.306852
https://doi.org/10.1074/jbc.m111.306852