Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Margaret A. Adelsman"'
Membrane localization of v-ErbB is required but not sufficient for ligand-independent transformation
Autor:
Nita J. Maihle, Margaret A. Adelsman, Trace A. Christensen, Denise C. Connolly, Courtney A. Lovejoy, Andrew J. Danielsen
Publikováno v:
Experimental Cell Research. 296:285-293
The v-ErbB retroviral oncogene is a transduced, mutated copy of the avian EGF receptor gene, and its expression is sufficient to induce tumor formation in vivo. The structural alterations that release the oncogenic potential of the v-ErbB oncogene ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::891541b9b3874b77a05209e28ead105e
https://doi.org/10.1016/j.yexcr.2004.01.023
https://doi.org/10.1016/j.yexcr.2004.01.023
Publikováno v:
The EMBO journal. 20(6)
Stimulation of T cells via the CD3--T-cell receptor (TCR) complex results in rapid increases in beta 1 integrin-mediated adhesion via poorly defined intracellular signaling events. We demonstrate that TCR-mediated activation of beta 1 integrins requi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c0d6c495187c570b8e3df8f46581088
https://pubmed.ncbi.nlm.nih.gov/11250890
https://pubmed.ncbi.nlm.nih.gov/11250890
Publikováno v:
Molecular biology of the cell. 10(9)
Integrins and growth factor receptors are important participants in cellular adhesion and migration. The EGF receptor (EGFR) family of tyrosine kinases and the beta1-integrin adhesion receptors are of particular interest, given the implication for th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdb14bda129b46ca488a8eaf771a0d09
https://pubmed.ncbi.nlm.nih.gov/10473632
https://pubmed.ncbi.nlm.nih.gov/10473632
Mutant v-erbB products of avian c-erbB1 have previously been used to correlate structural domains of the receptor encoded by this proto-oncogene with tissue-specific transformation potential. In these studies, deletion of the ligand-binding domain of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78bd26bddf18343d65d5957717aa92e0
https://europepmc.org/articles/PMC190099/
https://europepmc.org/articles/PMC190099/
