Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Margaret A Snowden"'
Autor:
Helen A. Fletcher, Margaret A. Snowden, Bernard Landry, Wasima Rida, Iman Satti, Stephanie A. Harris, Magali Matsumiya, Rachel Tanner, Matthew K. O’Shea, Veerabadran Dheenadhayalan, Leah Bogardus, Lisa Stockdale, Leanne Marsay, Agnieszka Chomka, Rachel Harrington-Kandt, Zita-Rose Manjaly-Thomas, Vivek Naranbhai, Elena Stylianou, Fatoumatta Darboe, Adam Penn-Nicholson, Elisa Nemes, Mark Hatherill, Gregory Hussey, Hassan Mahomed, Michele Tameris, J Bruce McClain, Thomas G. Evans, Willem A. Hanekom, Thomas J. Scriba, Helen McShane
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
BCG vaccine confers only partial protection against tuberculosis. Here the authors show that the risk of tuberculosis infection and progression to disease in BCG-immunized children positively correlates with the frequency of activated HLA-DR+CD4+T ce
Externí odkaz:
https://doaj.org/article/edab3b0f77064ee189c1a3294bd52daa
Autor:
Tamzin Furtado, Samuel Franzen, Francois van Loggerenberg, Gwenaelle Carn, Shannon Grahek, Megan McBride, Maureen Power, Jennifer O'Reilly, Barbara Savarese, Margaret Ann Snowden, Gwynn Stevens, Almarie Uys, Trudie Lang
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 8, Iss 11, p e3225 (2014)
Externí odkaz:
https://doaj.org/article/771c08bec9f44df8bd3a9349b065abad
Autor:
Helen A. Fletcher, Margaret A. Snowden, Bernard Landry, Wasima Rida, Iman Satti, Stephanie A. Harris, Magali Matsumiya, Rachel Tanner, Matthew K. O’Shea, Veerabadran Dheenadhayalan, Leah Bogardus, Lisa Stockdale, Leanne Marsay, Agnieszka Chomka, Rachel Harrington-Kandt, Zita-Rose Manjaly-Thomas, Vivek Naranbhai, Elena Stylianou, Fatoumatta Darboe, Adam Penn-Nicholson, Elisa Nemes, Mark Hatherill, Gregory Hussey, Hassan Mahomed, Michele Tameris, J. Bruce McClain, Thomas G. Evans, Willem A. Hanekom, Thomas J. Scriba, Helen McShane
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-1 (2016)
Nature Communications 7, Article number: 11290 (2016); Published: 12 April 2016; Updated: 6 May 2016. The original version of this Article contained an error in the spelling of the author Mark Hatherill, which was incorrectly given as Mark Hatheril.
Externí odkaz:
https://doaj.org/article/b95da97828c544a898fe07abb1e26945
Autor:
Rhea N. Coler, Tracey A. Day, Ruth Ellis, Franco M. Piazza, Anna Marie Beckmann, Julie Vergara, Tom Rolf, Lenette Lu, Galit Alter, David Hokey, Lakshmi Jayashankar, Robert Walker, Margaret Ann Snowden, Tom Evans, Ann Ginsberg, Steven G. Reed, The TBVPX-113 Study Team
Publikováno v:
npj Vaccines, Vol 3, Iss 1, Pp 1-9 (2018)
NPJ Vaccines
NPJ Vaccines
Tuberculosis (TB) is the leading cause of infectious death worldwide. Development of improved TB vaccines that boost or replace BCG is a major global health goal. ID93 + GLA-SE is a fusion protein TB vaccine candidate combined with the Toll-like Rece
Autor:
Helen McShane, Bernard Landry, Matthew K. O'Shea, Thomas J. Scriba, Elena Stylianou, Gregory D Hussey, Julius Muller, Willem A. Hanekom, Stephanie A. Harris, Zita-Rose Manjaly Thomas, Hassan Mahomed, Lisa Stockdale, Iman Satti, Margaret A Snowden, Magali Matsumiya, Stanley Kimbung Mbandi, Leanne Marsay, J. Bruce McClain, Michele Tameris, Mark Hatherill, Rachel Tanner, Thomas G. Evans, Rachel Harrington-Kandt, Agnieszka Chomka, Helen A. Fletcher, Vivek Naranbhai
Publikováno v:
JCI Insight
Immune activation is associated with increased risk of tuberculosis (TB) disease in infants. We performed a case-control analysis to identify drivers of immune activation and disease risk. Among 49 infants who developed TB disease over the first 2 ye
Autor:
Julius Muller, Rachel Tanner, Magali Matsumiya, Margaret A. Snowden, Bernard Landry, Iman Satti, Stephanie A. Harris, Matthew K. O’Shea, Lisa Stockdale, Leanne Marsay, Agnieszka Chomka, Rachel Harrington-Kandt, Zita-Rose Manjaly Thomas, Vivek Naranbhai, Elena Stylianou, Stanley Kimbung Mbandi, Mark Hatherill, Gregory Hussey, Hassan Mahomed, Michele Tameris, J. Bruce McClain, Thomas G. Evans, Willem A. Hanekom, Thomas J. Scriba, Helen McShane, Helen A. Fletcher
Immune activation is associated with increased risk of tuberculosis (TB) disease in infants. We performed a case-control analysis to identify drivers of immune activation and disease risk. Among 49 infants who developed TB disease over the first two
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bab979e8ce32010c1639197f3a1c59d
Autor:
Colleen Krohn, Zhongkai Shi, Hadn Africa, Gregory D. Hussey, Bruce McClain, Yolande Brown, Hassan Mahomed, Søren T. Hoff, Lebohang Makhethe, Margaret A Snowden, Hennie Geldenhuys, Mark Hatherill, Elisma Schoeman, Angelique Kany Kany Luabeya, Thomas J. Scriba, Sara Suliman, Cheryl L. Day, Ingrid Kromann, Erica Smit, Michele Tameris, E. Jane Hughes, Peter Bang, Benjamin M. Kagina, Peter Andersen, Willem A. Hanekom
Publikováno v:
Vaccine. 33:4130-4140
Background H56:IC31 is a candidate tuberculosis vaccine comprising a fusion protein of Ag85B, ESAT-6 and Rv2660c, formulated in IC31 adjuvant. This first-in-human, open label phase I trial assessed the safety and immunogenicity of H56:IC31 in healthy
Autor:
Dereck Tait, Willem A. Hanekom, Mark Hatherill, Ruth D. Ellis, Margaret A Snowden, Gavin J. Churchyard, Thomas J. Evans, Ann M. Ginsberg
Publikováno v:
Tuberculosis. 95:352-357
A recent trial of a leading tuberculosis (TB) vaccine candidate in 3000 South African infants failed to show protection over that from BCG alone, and highlights the difficulties in clinical development of TB vaccines. Progression of vaccine candidate
Autor:
Gavin J. Churchyard, Bernard Landry, Margaret A Snowden, Macaya Douoguih, J. Bruce McClain, Maria Grazia Pau, David A. Hokey, J. Sadoff, Veerabadran Dheenadhayalan
Publikováno v:
Vaccine. 33:1890-1896
Background The safety and immunogenicity of a replication deficient adenovirus serotype 35 tuberculosis (TB) vaccine containing gene inserts for Antigens (Ag) 85A, Ag85B and TB10.4 (AERAS-402/AD35.TB-S) was evaluated in previously BCG vaccinated, HIV
Autor:
Macaya Douoguih, Willem A. Hanekom, Andrew Graves, Benjamin M. Kagina, Jacqueline G. Benko, Jonathan G. Goldin, Maria Grazia Pau, Richard N. van Zyl-Smit, Rodney Dawson, Mary Bateman, Aliasgar Esmail, Barbara Shepherd, Margaret A Snowden, Thomas J. Scriba, Eric D. Bateman, David A. Hokey, Eva M. van Rikxoort, Jerald C. Sadoff, Sadritdin Ishmukhamedov, Brian Abel, Kathryn Tucker Rutkowski, J. Bruce McClain
Publikováno v:
American Journal of Respiratory and Critical Care Medicine, 195, 9, pp. 1171-1180
American Journal of Respiratory and Critical Care Medicine, 195, 1171-1180
American Journal of Respiratory and Critical Care Medicine, 195, 1171-1180
Item does not contain fulltext RATIONALE: Administration of tuberculosis (TB) vaccines in participants with previous or current pulmonary TB may have the potential for causing harmful postvaccination immunologic (Koch-type) reactions. OBJECTIVES: To
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82525e5c44ffaea8e5434c3e4b67de0d
https://hdl.handle.net/2066/175095
https://hdl.handle.net/2066/175095