Zobrazeno 1 - 10
of 667
pro vyhledávání: '"Margaret A Johnson"'
Publikováno v:
CNS Oncology, Vol 13, Iss 1 (2024)
Atypical teratoid rhabdoid tumors (AT/RT) are rare and highly malignant CNS neoplasms primarily affecting children. Adult cases are extremely uncommon, with only approximately 92 reported. Spinal AT/RT in adults is particularly rare. Here, we present
Externí odkaz:
https://doaj.org/article/cd857815a19b432e8eadd3284cc3f6ef
Autor:
Anmin Jiang, Kye Kudo, Rachel S. Gormal, Sevannah Ellis, Sikao Guo, Tristan P. Wallis, Shanley F. Longfield, Phillip J. Robinson, Margaret E. Johnson, Merja Joensuu, Frédéric A. Meunier
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract Endocytosis requires a coordinated framework of molecular interactions that ultimately lead to the fission of nascent endocytic structures. How cytosolic proteins such as dynamin concentrate at discrete sites that are sparsely distributed ac
Externí odkaz:
https://doaj.org/article/417850cc6c004c93857d76a6f63cbd31
Autor:
Amanda Mocroft, Jens D Lundgren, Michael Ross, Matthew Law, Peter Reiss, Ole Kirk, Colette Smith, Deborah Wentworth, Jacqueline Neuhaus, Christoph A Fux, Olivier Moranne, Phillipe Morlat, Margaret A Johnson, Lene Ryom, D:A:D study group, Royal Free Hospital Clinic Cohort, INSIGHT study group, SMART study group, ESPRIT study group
Publikováno v:
PLoS Medicine, Vol 12, Iss 3, p e1001809 (2015)
BackgroundChronic kidney disease (CKD) is a major health issue for HIV-positive individuals, associated with increased morbidity and mortality. Development and implementation of a risk score model for CKD would allow comparison of the risks and benef
Externí odkaz:
https://doaj.org/article/c2835c92bbb149ffb2fbec1962f07abc
Autor:
Rodrigo Funes‐Ferrada, Alanna Barrios‐Ruiz, Alejandra Yu Lee‐Mateus, Margaret M. Johnson, Sebastian Fernandez‐Bussy, David Abia‐Trujillo
Publikováno v:
Respirology Case Reports, Vol 12, Iss 5, Pp n/a-n/a (2024)
Abstract Expiratory central airway collapse (ECAC) comprising excessive central airway collapse (EDAC) and tracheobronchomalacia. Treatment is challenging for severe cases that are not candidates for surgical management. We report a case of severe EC
Externí odkaz:
https://doaj.org/article/6e2692f9ccfc4bc18bcd5882738371a1
Publikováno v:
eLife, Vol 12 (2023)
For HIV virions to become infectious, the immature lattice of Gag polyproteins attached to the virion membrane must be cleaved. Cleavage cannot initiate without the protease formed by the homo-dimerization of domains linked to Gag. However, only 5% o
Externí odkaz:
https://doaj.org/article/f429d0c25bae4a3988780ff432d687a4
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-21 (2022)
Abstract Proteins that drive processes like clathrin-mediated endocytosis (CME) are expressed at copy numbers within a cell and across cell types varying from hundreds (e.g. auxilin) to millions (e.g. clathrin). These variations contain important inf
Externí odkaz:
https://doaj.org/article/655ec900a0dd416394f760e00c23e0bf
Autor:
Fabiana Diaz‐Churion, Alejandra Yu Lee‐Mateus, David Abia‐Trujillo, Margaret M. Johnson, Andras Khoor, Neal M. Patel, Janani Reisenauer, Sebastian Fernandez‐Bussy
Publikováno v:
Respirology Case Reports, Vol 11, Iss 3, Pp n/a-n/a (2023)
Abstract Robotic‐assisted bronchoscopy (RAB) improves endoscopic diagnostic yield of solitary pulmonary nodules (SPN). Needle‐based confocal laser endomicroscopy (nCLE) is an emerging technology that allows high‐resolution, in‐vivo, real‐ti
Externí odkaz:
https://doaj.org/article/ffa258532f4542bcb6b0d25ced54a3aa
Autor:
Luxsena Sukumaran, Davide De Francesco, Alan Winston, Patrick W. G. Mallon, Nicki Doyle, Jane Anderson, Marta Boffito, Ian Williams, Frank A. Post, Jaime Vera, Memory Sachikonye, Margaret A. Johnson, Caroline A. Sabin
Publikováno v:
Frontiers in Systems Biology, Vol 3 (2023)
Introduction: As people living with HIV age, the increasing burden of multimorbidity poses a significant health challenge. The aims of this study were to identify common patterns of multimorbidity and examine changes in their burden, as well as their
Externí odkaz:
https://doaj.org/article/b82cb866df1849ac8c9a36a4a2e69afa
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 3, p e1009969 (2022)
Clathrin-coated structures must assemble on cell membranes to internalize receptors, with the clathrin protein only linked to the membrane via adaptor proteins. These structures can grow surprisingly large, containing over 20 clathrin, yet they often
Externí odkaz:
https://doaj.org/article/eca754f7ade44519805ba3b06765e7d4
Autor:
Alejandra Yu Lee-Mateus, Nikitha C. Chandra, Margaret M. Johnson, David Abia-Trujillo, Janani Reisenauer, Sebastian Fernandez-Bussy
Publikováno v:
Respiration. :1-5
Bronchoscopic biopsy of peripheral pulmonary nodules has evolved in recent years with the emergence of new technologies such as shape-sensing robotic-assisted bronchoscopy. The use of three-dimensional (3D) fluoroscopy for intraoperative visualizatio