Zobrazeno 1 - 10
of 312
pro vyhledávání: '"Margaret, Warner"'
Autor:
Zhenle Zang, Huachun Yin, Zhulin Du, Ruxin Xie, Ling Yang, Yun Cai, Liuyongwei Wang, Dandan Zhang, Xin Li, Tianyao Liu, Hong Gong, Junwei Gao, Hui Yang, Margaret Warner, Jan-Ake Gustafsson, Haiwei Xu, Xiaotang Fan
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Valproic acid (VPA) exposure during pregnancy leads to a higher risk of autism spectrum disorder (ASD) susceptibility in offspring. Human dorsal forebrain organoids were used to recapitulate course of cortical neurogenesis in the developing human bra
Externí odkaz:
https://doaj.org/article/7875d3f5d05146f08e2b5231e1db2430
Autor:
Xiaoyu Song, Wanfu Wu, Yubing Dai, Margaret Warner, Ivan Nalvarte, Per Antonson, Mukesh Varshney, Jan-Åke Gustafsson
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 15, p 12461 (2023)
Liver X receptors (LXRα and LXRβ) are oxysterol-activated nuclear receptors that play key roles in cholesterol homeostasis, the central nervous system, and the immune system. We have previously reported that LXRαβ-deficient mice are more suscepti
Externí odkaz:
https://doaj.org/article/bdae6b7e1a6e4f4b9d2428fcc414948b
Publikováno v:
Biomedicines, Vol 10, Iss 9, p 2165 (2022)
In this review, we discuss the role of liver X receptors (LXRs) in glial cells (microglia, oligodendrocytes and astrocytes) in the central nervous system (CNS). LXRs are oxysterol-activated nuclear receptors that, in adults, regulate genes involved i
Externí odkaz:
https://doaj.org/article/64e63d034d174950b5340830d48d0a70
Autor:
Jonas Abdel-Khalik, Eylan Yutuc, Peter J. Crick, Jan-Åke Gustafsson, Margaret Warner, Gustavo Roman, Kevin Talbot, Elizabeth Gray, William J. Griffiths, Martin R. Turner, Yuqin Wang
Publikováno v:
Journal of Lipid Research, Vol 58, Iss 1, Pp 267-278 (2017)
As neurons die, cholesterol is released in the central nervous system (CNS); hence, this sterol and its metabolites may represent a biomarker of neurodegeneration, including in amyotrophic lateral sclerosis (ALS), in which altered cholesterol levels
Externí odkaz:
https://doaj.org/article/9d8e6d3705504fb48c95baea8195e5c8
Autor:
Merianne Spencer, Margaret Warner, Jodi Cisewski, Arialdi Miniño, David Dodds, Janaka Perera, Farida Ahmad
This report provides national drug overdose death rates involving fentanyl, methamphetamine, cocaine, heroin, and oxycodone by sex, age, race and Hispanic origin, and public health region.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c9d4752a8cbc8d033e74d8b6747fc018
https://doi.org/10.15620/cdc:125504
https://doi.org/10.15620/cdc:125504
Autor:
David J. Kuter, Merlin Efraim, Jiri Mayer, Marek Trněný, Vickie McDonald, Robert Bird, Thomas Regenbogen, Mamta Garg, Zane Kaplan, Nikolay Tzvetkov, Philip Y. Choi, A.J. Gerard Jansen, Milan Kostal, Ross Baker, Jaromir Gumulec, Eun-Ju Lee, Ilona Cunningham, Isaac Goncalves, Margaret Warner, Ralph Boccia, Terry Gernsheimer, Waleed Ghanima, Olga Bandman, Regan Burns, Ann Neale, Dolca Thomas, Puneet Arora, Beiyao Zheng, Nichola Cooper
Publikováno v:
New England Journal of Medicine, 386(15), 1421-1431. Massachussetts Medical Society
BACKGROUND Rilzabrutinib, an oral, reversible covalent inhibitor of Bruton's tyrosine kinase, may increase platelet counts in patients with immune thrombocytopenia by means of dual mechanisms of action: decreased macrophage (Fcγ receptor)-mediated p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c172dc9093fbc35c4c4cf3aff5170e5c
https://doi.org/10.1056/nejmoa2110297
https://doi.org/10.1056/nejmoa2110297
Autor:
Rebecca H, Bitsko, Angelika H, Claussen, Jesse, Lichstein, Lindsey I, Black, Sherry Everett, Jones, Melissa L, Danielson, Jennifer M, Hoenig, Shane P, Davis Jack, Debra J, Brody, Shiromani, Gyawali, Matthew J, Maenner, Margaret, Warner, Kristin M, Holland, Ruth, Perou, Alex E, Crosby, Stephen J, Blumberg, Shelli, Avenevoli, Jennifer W, Kaminski, Reem M, Ghandour, Leah N, Meyer
Publikováno v:
MMWR Supplements. 71:1-42
Mental health encompasses a range of mental, emotional, social, and behavioral functioning and occurs along a continuum from good to poor. Previous research has documented that mental health among children and adolescents is associated with immediate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62b282b1e14246b10cb10d37555af823
https://doi.org/10.15585/mmwr.su7102a1
https://doi.org/10.15585/mmwr.su7102a1
Publikováno v:
Journal of Molecular Endocrinology. 68:R1-R9
Summary After the discovery of ERβ, a novel role for dihydrotestosterone (DHT) in estrogen signaling was revealed. Instead of just being a better androgen, DHT was found to be a precursor of the ERβ agonist 5α-androstane-3β, 17β-diol (3βAdiol),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bdea9c92ff8ec1826ff39c231cd6b90
https://doi.org/10.1530/jme-21-0121
https://doi.org/10.1530/jme-21-0121
Publikováno v:
NCHS data brief. (457)
Drug overdose deaths have been rising over the past 2 decades in the United States (1-4). This report uses the most recent data from the National Vital Statistics System (NVSS) to update statistics on deaths from drug overdose in the United States, s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::921c301f718dcd067e7fdebc0fdaac81
https://pubmed.ncbi.nlm.nih.gov/36598401
https://pubmed.ncbi.nlm.nih.gov/36598401