Zobrazeno 1 - 10 of 100 pro vyhledávání: '"Margalit Efrati"'
1
Diffusing Alpha-Emitters Radiation Therapy Promotes a Proimmunogenic Tumor Microenvironment and Synergizes With Programmed Cell Death Protein 1 Blockade
Autor: Sara Del, Mare, Yossi, Nishri, Amit, Shai, Margalit, Efrati, Lisa, Deutsch, Robert B, Den, Itzhak, Kelson, Yona, Keisari, Vered, Domankevich
Publikováno v: International Journal of Radiation Oncology*Biology*Physics. 115:707-718
Diffusing alpha-emitters Radiation Therapy (DaRT) releases alpha-emitting atoms into the tumor microenvironment. The treatment effectively ablates human and mice xenografts and shows 100% response rates in skin or head and neck squamous cell carcinom
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b030324251fa56f5747e8a13c0853b3d
https://doi.org/10.1016/j.ijrobp.2022.08.043
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2
Akademický článek
RIG-1-Like Receptor Activation Synergizes With Intratumoral Alpha Radiation to Induce Pancreatic Tumor Rejection, Triple-Negative Breast Metastases Clearance, and Antitumor Immune Memory in Mice
Autor: Vered Domankevich, Margalit Efrati, Michael Schmidt, Eran Glikson, Fairuz Mansour, Amit Shai, Adi Cohen, Yael Zilberstein, Elad Flaisher, Razvan Galalae, Itzhak Kelson, Yona Keisari
Publikováno v: Frontiers in Oncology, Vol 10 (2020)
Diffusing alpha-emitting radiation therapy (DaRT) employs intratumoral Ra-224-coated seeds that efficiently destroy solid tumors by slowly releasing alpha-emitting atoms inside the tumor. In immunogenic tumor models, DaRT was shown to activate system
Externí odkaz: https://doaj.org/article/23fa0247ceb54ed68d69c6fe4badcc7e
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4
Akademický článek
Quantification of Two Fluorophores’ Concentration Ratio in a Mice Model in Preparation for a Proposed Method for Early Detection of Alzheimer’s Disease
Autor: Osnat Harbater, Margalit Efrati, Israel Gannot
Publikováno v: Applied Sciences, Vol 8, Iss 5, p 745 (2018)
Many biomedical applications require concentration measurements of biological compounds, which may be achieved using targeted fluorescent probes. It has been shown that the ratio between amyloid-Beta and tau protein in the cerebrospinal fluid (CSF) i
Externí odkaz: https://doaj.org/article/d056f9eebd2745d3aab07c285ae7c629
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5
Akademický článek
Human apoE3 but not apoE4 rescues impaired astrocyte activation in apoE null mice
Autor: Gal Ophir, Sigal Meilin, Margalit Efrati, Joab Chapman, Dimitri Karussis, Allen Roses, Daniel M Michaelson
Publikováno v: Neurobiology of Disease, Vol 12, Iss 1, Pp 56-64 (2003)
The allele E4 of apolipoprotein E (apoE) is an important risk factor for Alzheimer’s disease (AD) and the chronic brain inflammation which is associated with AD is more pronounced in subjects who carry this allele. In the present study, we employed
Externí odkaz: https://doaj.org/article/aa14c8444e1846f8acaf71a89d61fce5
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7
Combining alpha radiation-based brachytherapy with immunomodulators promotes complete tumor regression in mice via tumor-specific long-term immune response
Autor: Michael Schmidt, Hans-Georg Rammensee, Sujit S. Nair, Itzhak Kelson, Margalit Efrati, Ashutosh K. Tewari, Adi Cohen, Vered Domankevich, Yona Keisari
Publikováno v: Cancer Immunology, Immunotherapy
Diffusing alpha-emitters radiation therapy (DaRT) is the only known method for treating solid tumors with highly destructive alpha radiation. More importantly, as a monotherapy, DaRT has been shown to induce a systemic antitumor immune response follo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61ba093144a48274158613d2afe20834
https://pubmed.ncbi.nlm.nih.gov/31637474
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9
Quantification of Two Fluorophores’ Concentration Ratio in a Mice Model in Preparation for a Proposed Method for Early Detection of Alzheimer’s Disease
Autor: Israel Gannot, Osnat Harbater, Margalit Efrati
Publikováno v: Applied Sciences; Volume 8; Issue 5; Pages: 745
Applied Sciences, Vol 8, Iss 5, p 745 (2018)
Many biomedical applications require concentration measurements of biological compounds, which may be achieved using targeted fluorescent probes. It has been shown that the ratio between amyloid-Beta and tau protein in the cerebrospinal fluid (CSF) i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d0f3c6adcebdf1844d3d8ad5b18ede9
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