Molecular Regulation of Bone Turnover in Juvenile Idiopathic Arthritis: Animal Models, Cellular Features and TNFα

Autor: Harry C Blair, Jonathan Soboloff, Irina L Tourkova, Jamie L. McCall, Suravi Ray, Margalit E Rosenkranz, Cristina Sobacchi, Lisa J Robinson, John B Barnett

Publikováno v: Frontiers in Bioscience-Landmark, Vol 29, Iss 7, p 248 (2024)

We review the abnormal bone turnover that is the basis of idiopathic inflammatory or rheumatoid arthritis and bone loss, with emphasis on Tumor Necrosis Factor-alpha (TNFα)-related mechanisms. We review selected data on idiopathic arthritis in juven

Externí odkaz: https://doaj.org/article/8affe27a801d44a09bf66b64021e954b

Relentless placoid chorioretinitis: A review of four cases in pediatric and young adult patients with a discussion of therapeutic strategies

Autor: Haniah A. Zaheer, Jamie Odden, Meghal Gagrani, Fatma Zaguia, Careen Lowder, Andreea Coca, Margalit E. Rosenkranz, Preeti Patil-Chhablani, Raphaelle Ores, Francois Boussion, Chad Indermill, José-Alain Sahel, Ken Nischal, Debra A. Goldstein, Marie-Helene Errera

Publikováno v: Frontiers in Pediatrics, Vol 11 (2023)

IntroductionRelentless placoid chorioretinitis (RPC) is a rare, bilateral disease of the retinal pigment epithelium. The clinical course is prolonged and relapsing. No standard treatment has been established to date. The purpose of this case series i

Externí odkaz: https://doaj.org/article/cced4da45bb5492fbc58980b4be2792e

Analysis of user trends in digital health communities using big data mining.

Autor: Keinan R; Department of Computer Science, Lev Academic Center, Jerusalem College of Technology, Jerusalem, Israel., Margalit E; Department of Computer Science, Lev Academic Center, Jerusalem College of Technology, Jerusalem, Israel., Bouhnik D; Department of Computer Science, Lev Academic Center, Jerusalem College of Technology, Jerusalem, Israel.

Publikováno v: PloS one [PLoS One] 2024 Aug 26; Vol. 19 (8), pp. e0290803. Date of Electronic Publication: 2024 Aug 26 (Print Publication: 2024).

A unifying framework for functional organization in early and higher ventral visual cortex.

Autor: Margalit E; Neurosciences Graduate Program, Stanford University, Stanford, CA 94305, USA. Electronic address: eshed.margalit@gmail.com., Lee H; Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139, USA., Finzi D; Department of Psychology, Stanford University, Stanford, CA 94305, USA; Department of Computer Science, Stanford University, Stanford, CA 94305, USA., DiCarlo JJ; Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Center for Brains Minds and Machines, Massachusetts Institute of Technology, Cambridge, MA 02139, USA., Grill-Spector K; Department of Psychology, Stanford University, Stanford, CA 94305, USA; Wu Tsai Neurosciences Institute, Stanford University, Stanford, CA 94305, USA., Yamins DLK; Department of Psychology, Stanford University, Stanford, CA 94305, USA; Department of Computer Science, Stanford University, Stanford, CA 94305, USA; Wu Tsai Neurosciences Institute, Stanford University, Stanford, CA 94305, USA.

Publikováno v: Neuron [Neuron] 2024 Jul 17; Vol. 112 (14), pp. 2435-2451.e7. Date of Electronic Publication: 2024 May 10.

T Cell Receptor-Independent, CD31/IL-17A-Driven Inflammatory Axis Shapes Synovitis in Juvenile Idiopathic Arthritis

Autor: Ian D. Ferguson, Patricia Griffin, Joshua J. Michel, Hiroshi Yano, Sarah L. Gaffen, Robert G. Mueller, Jeffrey A. Dvergsten, Jon D. Piganelli, Margalit E. Rosenkranz, Daniel A. Kietz, Abbe N. Vallejo

Publikováno v: Frontiers in Immunology, Vol 9 (2018)

T cells are considered autoimmune effectors in juvenile idiopathic arthritis (JIA), but the antigenic cause of arthritis remains elusive. Since T cells comprise a significant proportion of joint-infiltrating cells, we examined whether the environment

Externí odkaz: https://doaj.org/article/757c2d5e02994195bbce2ee52debeb3b