Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Margalida Rotger"'
Autor:
Javier Martinez-Picado, Paul J. McLaren, Itziar Erkizia, Maureen P. Martin, Susana Benet, Margalida Rotger, Judith Dalmau, Dan Ouchi, Steven M. Wolinsky, Sudhir Penugonda, Huldrych F. Günthard, Jacques Fellay, Mary Carrington, Nuria Izquierdo-Useros, Amalio Telenti
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-7 (2016)
Binding of virus, HIV-1, to cellular protein Siglec-1 is important for infection of immune cells. Here the authors show that a natural mutation leading to production of truncated Siglec-1 reduces HIV binding and infectivity transfer in vitro, but doe
Externí odkaz:
https://doaj.org/article/959f141fdeb24fdea52d8605fca12220
Autor:
Nathan W. Cummins, Jacqueline Neuhaus, Haitao Chu, James Neaton, Christoph Wyen, Jürgen K. Rockstroh, Daniel J. Skiest, Mark A. Boyd, Saye Khoo, Margalida Rotger, Amalio Telenti, Richard Weinshilboum, Andrew D. Badley
Publikováno v:
EBioMedicine, Vol 2, Iss 7, Pp 706-712 (2015)
Background: Efavirenz (EFV) based antiretroviral therapy is expanding worldwide. However discontinuation of EFV containing regimens is common in some patients, particularly black patients, due most often to neuropsychiatric side effects. These advers
Externí odkaz:
https://doaj.org/article/b06c99aa97ef4a24a4db61e3fba56276
Autor:
Helen Kovari, Stefan Russmann, Bruno Ledergerber, Daniel Müller, Margalida Rotger, Pablo Velli, Matthias Cavassini, Juan Ambrosioni, Andrea Bregenzer, Marcel Stöckle, Enos Bernasconi, Andri Rauch, Roberto F Speck, Swiss HIV Cohort Study
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0133879 (2015)
Ribavirin (RBV) is an essential component of most current hepatitis C (HCV) treatment regimens and still standard of care in the combination with pegylated interferon (pegIFN) to treat chronic HCV in resource limited settings. Study results in HIV/HC
Externí odkaz:
https://doaj.org/article/3bc3e031088548a5999f863df2410cdd
Autor:
M. Guidi, Mona Arab-Alameddine, Margalida Rotger, Manel Aouri, Amalio Telenti, Laurent A. Decosterd, Thierry Buclin, Chantal Csajka
Publikováno v:
CHIMIA, Vol 66, Iss 5 (2012)
Pharmacokinetic variability in drug levels represent for some drugs a major determinant of treatment success, since sub-therapeutic concentrations might lead to toxic reactions, treatment discontinuation or inefficacy. This is true for most antiretro
Externí odkaz:
https://doaj.org/article/3a79cf769bba41729437f48593d67ad7
Autor:
Tracy R Glass, Margalida Rotger, Amalio Telenti, Laurent Decosterd, Chantal Csajka, Heiner C Bucher, Huldrych F Günthard, Martin Rickenbach, Dunja Nicca, Bernard Hirschel, Enos Bernasconi, Gilles Wandeler, Manuel Battegay, Catia Marzolini, Swiss HIV Cohort Study
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e29186 (2012)
BackgroundGood adherence to antiretroviral therapy (ART) is critical for successful HIV treatment. However, some patients remain virologically suppressed despite suboptimal adherence. We hypothesized that this could result from host genetic factors i
Externí odkaz:
https://doaj.org/article/e7c083a016aa471fa1e1875c14944286
Autor:
Margalida Rotger, Kristen K Dang, Jacques Fellay, Erin L Heinzen, Sheng Feng, Patrick Descombes, Kevin V Shianna, Dongliang Ge, Huldrych F Günthard, David B Goldstein, Amalio Telenti, Swiss HIV Cohort Study, Center for HIV/AIDS Vaccine Immunology
Publikováno v:
PLoS Pathogens, Vol 6, Iss 2, p e1000781 (2010)
There is great interindividual variability in HIV-1 viral setpoint after seroconversion, some of which is known to be due to genetic differences among infected individuals. Here, our focus is on determining, genome-wide, the contribution of variable
Externí odkaz:
https://doaj.org/article/70b9ed040f53413f865b468509610dbd
Publikováno v:
Zdravniški Vestnik, Vol 72, Iss 10 (2003)
Background. Nasal carriage of Staphylococcus aureus is an important risk factor for later infection with the same strain. Topical mupirocin is used for S. aureus nasal decolonization. However, due to increasing mupirocin misuse resistance may develop
Externí odkaz:
https://doaj.org/article/541ddb1770f24779a80310ac8365a7e3
Autor:
Aparna Ponnurangam, Thomas Krey, George Ssebyatika, Veronika Lodermeyer, Margalida Rotger, Vânia Passos, Angelina Malassa, Ellen Ewald, Amalio Telenti, Christine S. Falk, Christina M. Stürzel, Christine Goffinet, Frank Kirchhoff
Publikováno v:
Journal of virology
Journal of Virology
Journal of virology, vol. 92, no. 14, pp. 1
Journal of Virology
Journal of virology, vol. 92, no. 14, pp. 1
Cellular antiviral proteins interfere with distinct steps of replication cycles of viruses. The galectin 3 binding protein (LGALS3BP, also known as 90K) was previously shown to lower the infectivity of nascent human immunodeficiency virus type 1 (HIV
Autor:
Daniel J. Skiest, Jürgen K. Rockstroh, James D. Neaton, Christoph Wyen, Jacqueline Neuhaus, Andrew D. Badley, Margalida Rotger, Richard M. Weinshilboum, Amalio Telenti, Mark A. Boyd, Saye Khoo, Nathan W. Cummins, Haitao Chu
Publikováno v:
EBioMedicine, Vol 2, Iss 7, Pp 706-712 (2015)
Ebiomedicine, vol. 2, no. 7, pp. 706-712
EBioMedicine
Ebiomedicine, vol. 2, no. 7, pp. 706-712
EBioMedicine
Background Efavirenz (EFV) based antiretroviral therapy is expanding worldwide. However discontinuation of EFV containing regimens is common in some patients, particularly black patients, due most often to neuropsychiatric side effects. These adverse
Autor:
Stefan P. Kuster, Laurent A. Decosterd, Margalida Rotger, Huldrych F. Günthard, Amalio Telenti, Manel Aouri, Alexia Anagnostopoulos
Publikováno v:
Antiviral Therapy. 18:739-743
Here, we describe severe neuropsychiatric symptoms in an HIV-positive Asian man with extremely high efavirenz plasma levels while receiving standard treatment with efavirenz/tenofovir/emtricitabine fixed-dose regimen. Genetic examination revealed com