Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Maretoshi Hirai"'
Centrioles are frequently amplified in early B cell development but dispensable for humoral immunity
Autor:
Marina A. Schapfl, Gina M. LoMastro, Vincent Z. Braun, Maretoshi Hirai, Michelle S. Levine, Eva Kiermaier, Verena Labi, Andrew J. Holland, Andreas Villunger
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Centrioles define centrosome structure and function. Deregulation of centriole numbers can cause developmental defects and cancer. The p53 tumor suppressor limits the growth of cells lacking or harboring additional centrosomes and can be eng
Externí odkaz:
https://doaj.org/article/019d4fb19cb64cd6834d48d84c0fafe0
Autor:
Kiichi Hirota, Maretoshi Hirai
Publikováno v:
Reports, Vol 5, Iss 4, p 40 (2022)
Consumer rhythm-monitoring devices, such as the Apple Watch, are becoming more readily available. Irregular pulses can be detected using an optical sensor that is built into the wearable device. The Apple Watch (Apple Inc., Cupertino, CA, USA) is a c
Externí odkaz:
https://doaj.org/article/b652349f09cb44dd910825eb8368314a
Publikováno v:
Journal of Clinical Investigation. 127:569-582
Failure of trabecular myocytes to undergo appropriate cell cycle withdrawal leads to ventricular noncompaction and heart failure. Signaling of growth factor receptor ERBB2 is critical for myocyte proliferation and trabeculation. However, the mechanis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dd10197a22b1dd1997db86d3b04c77e
https://doi.org/10.1172/jci91081
https://doi.org/10.1172/jci91081
Publikováno v:
Genesis (New York, N.y. : 2000)
Summary Centrosomes are major microtubule organizing centers (MTOCs) that play an important role in chromosome segregation during cell division. Centrosomes provide a stable anchor for microtubules, constituting the centers of the spindle poles in mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11df53654da8e5d004e6636f7ed11e9c
https://doi.org/10.1002/dvg.22937
https://doi.org/10.1002/dvg.22937
Publikováno v:
Circulation research, vol 118, iss 6
No Evidence for Cardiomyocyte Number Expansion in Preadolescent Mice Alkass et al Cell . 2015;163:1026–1036. Understanding cardiomyocyte cell cycle regulation after birth is key to optimizing regenerative strategies for the heart post injury, yet p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d681536e5128bc4e4f03a509b6b0d0e8
https://escholarship.org/uc/item/938347st
https://escholarship.org/uc/item/938347st
Publikováno v:
Circulation research, vol 118, iss 1
Rationale : Discerning cardiac myocyte cell cycle behavior is challenging owing to commingled cell types with higher proliferative activity. Objective : To investigate cardiac myocyte cell cycle activity in development and the early postnatal period.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cd22674497fd00813a3c4e10ad26fa5
https://escholarship.org/uc/item/9g9667m6
https://escholarship.org/uc/item/9g9667m6
Autor:
Masahito Horiguchi, Akari Hagiwara, Tomoyuki Nakamura, Toru Kita, Tetsuya Ohbayashi, Katsuya Okawa, Maretoshi Hirai, Kenneth R. Chien
Publikováno v:
The Journal of Cell Biology
Elastic fibers are required for the elasticity and integrity of various organs. We and others previously showed that fibulin-5 (also called developing arteries and neural crest EGF-like [DANCE] or embryonic vascular EGF-like repeat–containing prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92371a60b4b6e90568c56186b5f2684e
http://europepmc.org/articles/PMC2064089
http://europepmc.org/articles/PMC2064089
Autor:
Ofer Shoshani, Yin Wang, Benjamin Vitre, Maretoshi Hirai, Don W. Cleveland, Jihane Boubaker, Thomas Cho, Lino Tessarollo, Deborah A. Swing, Sylvia M. Evans, Anita Kulukian, Andrew J. Holland, Marcus Maldonado, Elaine Fuchs
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 112, iss 46
Centrosomes are microtubule-organizing centers that facilitate bipolar mitotic spindle assembly and chromosome segregation. Recognizing that centrosome amplification is a common feature of aneuploid cancer cells, we tested whether supernumerary centr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d29825f2958b685c67083f4c8d2d7573
https://europepmc.org/articles/PMC4655534/
https://europepmc.org/articles/PMC4655534/
Autor:
Tatsuya Morimoto, Toshio Heike, Tatsutoshi Nakahata, Maretoshi Hirai, Teruhisa Kawamura, Hiromichi Wada, Koji Hasegawa, Takayuki Morisaki, Toru Kita, Koh Ono, Kyoko Hidaka
Publikováno v:
Journal of Biological Chemistry. 280:19682-19688
Differentiation of embryonic stem (ES) cells into cardiac myocytes requires activation of a cardiac-specific gene program. Histone acetyltransferases (HATs) and histone deacetylases (HDACs) govern gene expression patterns by being recruited to target
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32093b2166c973aa5ec352e19856dc0c
https://doi.org/10.1074/jbc.m412428200
https://doi.org/10.1074/jbc.m412428200
Autor:
Tatsuya Morimoto, Koh Ono, Maretoshi Hirai, Teruhisa Kawamura, Toru Kita, Koji Hasegawa, Hiromichi Wada
Publikováno v:
Journal of Biological Chemistry. 279:37640-37650
A multizinc finger protein, FOG-2, associates with a cardiac transcription factor, GATA-4, and represses GATA-4-dependent transcription. GATA-4 is required not only for normal heart development but is also involved in hypertrophic responses in cardia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cca4849fa5a8660c842cbdff4f06179
https://doi.org/10.1074/jbc.m401737200
https://doi.org/10.1074/jbc.m401737200