Bronchial thermoplasty: interventional therapy in asthma

Autor: Philine Kaukel, Felix J.F. Herth, Maren Schuhmann

Publikováno v: Therapeutic Advances in Respiratory Disease, Vol 8 (2014)

Bronchial thermoplasty is a new treatment option for patients with severe bronchial asthma who remain symptomatic despite maximal medical therapy. The aim of this interventional therapy option is the reduction of smooth muscle in the central and peri

Externí odkaz: https://doaj.org/article/2c4d43b38cde41b7a7c4f549dda03eb9

Switch from IL-5 to IL-5-Receptor α Antibody Treatment in Severe Eosinophilic Asthma

Autor: Christian Taube, Tobias Welte, Benjamin Seeliger, Felix J.F. Herth, Karl-Christian Bergmann, Juergen Behr, Stephanie Korn, Nikolaus Kneidinger, Katrin Milger, Hendrik Suhling, Jan Fuge, Roland Buhl, Maren Schuhmann, Nora Drick, Benjamin Kendziora

Publikováno v: Journal of Asthma and Allergy. 13:605-614

Background Anti-IL-5 antibodies represent an established therapy for severe eosinophilic asthma (SEA), but some patients show inadequate response. The objective of this study was to assess the effects of a switch to anti-IL-5Rα therapy in patients w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2397e866f22c9046021ddd636264f502
https://doi.org/10.2147/jaa.s270298

Prediction of anti-tuberculosis treatment duration based on a 22-gene transcriptomic model

Autor: Sebastian Marwitz, January Weiner, Thierry Rolling, Victor Spinu, Dörte Nitschkowski, Florian P. Maurer, Marius Müller, Jan Heyckendorf, Anna M. Mandalakas, Jan Rybniker, Torsten Goldmann, Maja Reimann, Michael Hoelscher, Markus Unnewehr, Korkut Avsar, Helmut J. F. Salzer, Elmira Ibraim, Ioana D. Olaru, Andrea Rachow, Gunar Günther, Frank van Leth, Maren Schuhmann, Dagmar Schaub, Christoph Lange, Barbara Kalsdorf, Cristina Popa, Elena Terhalle, Patricia Sanchez-Carballo, Irina Kontsevaya, Isabelle Suárez, Stefan H. E. Kaufmann, Andrew R. DiNardo

Publikováno v: European respiratory journal, 58(3):2003492. European Respiratory Society
Heyckendorf, Jan; Marwitz, Sebastian; Reimann, Maja; Avsar, Korkut; DiNardo, Andrew; Günther, Gunar; Hoelscher, Michael; Ibraim, Elmira; Kalsdorf, Barbara; Kaufmann, Stefan H E; Kontsevaya, Irina; van Leth, Frank; Mandalakas, Anna Maria; Maurer, Florian P; Müller, Marius; Nitschkowski, Dörte; Olaru, Ioana D; Popa, Cristina; Rachow, Andrea; Rolling, Thierry; ... (2021). Prediction of anti-tuberculosis treatment duration based on a 22-gene transcriptomic model. European respiratory journal, 58(3) European Respiratory Society 10.1183/13993003.03492-2020
European Respiratory Journal, 58(3):2003492, 1-13. European Respiratory Society
Heyckendorf, J, Marwitz, S, Reimann, M, Avsar, K, DiNardo, A R, Günther, G, Hoelscher, M, Ibraim, E, Kalsdorf, B, Kaufmann, S H E, Kontsevaya, I, van Leth, F, Mandalakas, A M, Maurer, F P, Müller, M, Nitschkowski, D, Olaru, I D, Popa, C, Rachow, A, Rolling, T, Rybniker, J, Salzer, H J F, Sanchez-Carballo, P, Schuhmann, M, Schaub, D, Spinu, V, Suárez, I, Terhalle, E, Unnewehr, M, Weiner, J, Goldmann, T & Lange, C 2021, ' Prediction of anti-tuberculosis treatment duration based on a 22-gene transcriptomic model ', European Respiratory Journal, vol. 58, no. 3, 2003492, pp. 1-13 . https://doi.org/10.1183/13993003.03492-2020

BackgroundThe World Health Organization recommends standardised treatment durations for patients with tuberculosis (TB). We identified and validated a host-RNA signature as a biomarker for individualised therapy durations for patients with drug-susce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef72f5ef3406b43fadab06b729aeb5be
https://pure.amc.nl/en/publications/prediction-of-antituberculosis-treatment-duration-based-on-a-22gene-transcriptomic-model(4a364caf-28af-4e65-80f0-2ab79f922338).html

Utility of Endobronchial Ultrasound in Assessment of Intrathoracic Lesions in Paediatric Patients

Autor: Ralf Eberhardt, John Massie, Sarath Ranganathan, Louis Irving, Daniel P Steinfort, Felix J.F. Herth, Maren Schuhmann, Shivanthan Shanthikumar

Publikováno v: Respiration. 98:340-346

Introduction: In adults, linear endobronchial ultrasound (EBUS) is the preferred modality to sample intrathoracic adenopathy and radial EBUS is a useful tool to biopsy peripheral pulmonary nodules. Utility in children is less well known. Objectives:

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e76d543c6775275c40b50b318fa2b6f
https://doi.org/10.1159/000501466

A 22-gene transcriptomic model indicating individual therapy durations in multidrug-resistant tuberculosis

Autor: Helmut J. F. Salzer, Barbara Kalsdorf, Sebastian Marwitz, Victor Spinu, Frank van Leth, Michael Hoelscher, Elmira Ibraim, Andrea Rachow, Maren Schuhmann, Marius Müller, Jan Heyckendorf, Dörte Nitschkowski, Korkut Avsar, Irina Kontsevaya, Isabelle Suárez, Stefan H. E. Kaufmann, Christoph Lange, Andrew R. DiNardo, Patricia Sanchez-Carballo, Elena Terhalle, Ioana D. Olaru, Jan Rybniker, Cristina Popa, Gunar Günther, Florian P. Maurer, Dagmar Schaub, January Weiner, Thierry Rolling, Markus Unnewehr, Anna M. Mandalakas, Torsten Goldmann, Maja Reimann

Emerging multidrug-resistant tuberculosis is a major global health challenge. The World Health Organization currently recommends treatment durations of 9–18 months or more for patients with multidrug-resistant tuberculosis. We identified and valida

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cd7fd7aa56c60682229863be629c339
https://doi.org/10.1101/2020.08.21.20177238