Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Maren Scharfe"'
Autor:
Kathrin Alpers, Elisabeth Vatareck, Lothar Gröbe, Mathias Müsken, Maren Scharfe, Susanne Häussler, Jürgen Tomasch
Publikováno v:
mSystems, Vol 8, Iss 2 (2023)
ABSTRACT Bacteria either duplicate their chromosome once per cell division or a new round of replication is initiated before the cells divide, thus cell cycles overlap. Here, we show that the opportunistic pathogen Pseudomonas aeruginosa switches fro
Externí odkaz:
https://doaj.org/article/6d451498c0cd4d009f2bd1c5ec6682ea
Autor:
Izabela J. Swierzy, Ulrike Händel, Alexander Kaever, Michael Jarek, Maren Scharfe, Dirk Schlüter, Carsten G. K. Lüder
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Abstract The apicomplexan parasite Toxoplasma gondii infects various cell types in avian and mammalian hosts including humans. Infection of immunocompetent hosts is mostly asymptomatic or benign, but leads to development of largely dormant bradyzoite
Externí odkaz:
https://doaj.org/article/f792f7d58180444994f3bde4f80e7e1b
Autor:
Sonja Koppenhöfer, Hui Wang, Maren Scharfe, Volkhard Kaever, Irene Wagner-Döbler, Jürgen Tomasch
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
Quorum sensing (QS) coordinates population wide gene expression of bacterial species. Highly adaptive traits like gene transfer agents (GTA), morphological heterogeneity, type 4 secretion systems (T4SS), and flagella are QS controlled in Dinoroseobac
Externí odkaz:
https://doaj.org/article/0b474a82cffb433ab139f4178c1ceade
Autor:
Katja Koeppen, Thomas H Hampton, Michael Jarek, Maren Scharfe, Scott A Gerber, Daniel W Mielcarz, Elora G Demers, Emily L Dolben, John H Hammond, Deborah A Hogan, Bruce A Stanton
Publikováno v:
PLoS Pathogens, Vol 12, Iss 6, p e1005672 (2016)
Bacterial outer membrane vesicle (OMV)-mediated delivery of proteins to host cells is an important mechanism of host-pathogen communication. Emerging evidence suggests that OMVs contain differentially packaged short RNAs (sRNAs) with the potential to
Externí odkaz:
https://doaj.org/article/cceee9c8232f4dbabd18829891c35879
Autor:
Dorte Bohla, Martin Herold, Imke Panzer, Melanie K Buxa, Tamer Ali, Jeroen Demmers, Marcus Krüger, Maren Scharfe, Michael Jarek, Marek Bartkuhn, Rainer Renkawitz
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107765 (2014)
Chromatin insulators of higher eukaryotes functionally divide the genome into active and inactive domains. Furthermore, insulators regulate enhancer/promoter communication, which is evident from the Drosophila bithorax locus in which a multitude of r
Externí odkaz:
https://doaj.org/article/98b2b417259442eca46af26921b9687d
Autor:
Katharina Schlereth, Charlotte Heyl, Anna-Maria Krampitz, Marco Mernberger, Florian Finkernagel, Maren Scharfe, Michael Jarek, Ellen Leich, Andreas Rosenwald, Thorsten Stiewe
Publikováno v:
PLoS Genetics, Vol 9, Iss 8, p e1003726 (2013)
p53 protects us from cancer by transcriptionally regulating tumor suppressive programs designed to either prevent the development or clonal expansion of malignant cells. How p53 selects target genes in the genome in a context- and tissue-specific man
Externí odkaz:
https://doaj.org/article/6c9c5e8d44a94f84b682b14adaaee1b6
Autor:
Andreas Dötsch, Denitsa Eckweiler, Monika Schniederjans, Ariane Zimmermann, Vanessa Jensen, Maren Scharfe, Robert Geffers, Susanne Häussler
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e31092 (2012)
In this study, we evaluated how gene expression differs in mature Pseudomonas aeruginosa biofilms as opposed to planktonic cells by the use of RNA sequencing technology that gives rise to both quantitative and qualitative information on the transcrip
Externí odkaz:
https://doaj.org/article/138b05846ea84acf9c64fae40d57ac6e
Autor:
Karin Meier, Eve-Lyne Mathieu, Florian Finkernagel, L Maximilian Reuter, Maren Scharfe, Gunther Doehlemann, Michael Jarek, Alexander Brehm
Publikováno v:
PLoS Genetics, Vol 8, Iss 5, p e1002676 (2012)
Mutations in the l(3)mbt tumour suppressor result in overproliferation of Drosophila larval brains. Recently, the derepression of different gene classes in l(3)mbt mutants was shown to be causal for transformation. However, the molecular mechanisms o
Externí odkaz:
https://doaj.org/article/5f87c05781644189a59d1321525ecaa4
Autor:
Till Adhikary, Kerstin Kaddatz, Florian Finkernagel, Anne Schönbauer, Wolfgang Meissner, Maren Scharfe, Michael Jarek, Helmut Blöcker, Sabine Müller-Brüsselbach, Rolf Müller
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e16344 (2011)
Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors with essential functions in lipid, glucose and energy homeostasis, cell differentiation, inflammation and metabolic disorders, and represent important drug targets. PPARs heter
Externí odkaz:
https://doaj.org/article/4bbf80cb4acd497f8dcab065e313d310
Autor:
Kathrin Alpers, Elisabeth Vatareck, Lothar Gröbe, Mathias Müsken, Maren Scharfe, Susanne Häussler, Jürgen Tomasch
In bacteria, either chromosome duplication is coupled to cell division with only one replication round per cell cycle or DNA is replicated faster than the cells divide thus both processes are uncoupled. Here, we show that the opportunistic pathogenPs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9144ba155d0c355b73973ab8dec2c009
https://doi.org/10.1101/2022.11.10.516079
https://doi.org/10.1101/2022.11.10.516079
