Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Maren Mieth"'
Autor:
Umer Bin Abdul Aziz, Ali Saoud, Marcel Bermudez, Maren Mieth, Amira Atef, Thomas Rudolf, Christoph Arkona, Timo Trenkner, Christoph Böttcher, Kai Ludwig, Angelique Hoelzemer, Andreas C. Hocke, Gerhard Wolber, Jörg Rademann
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Pneumolysin (PLY) is a cholesterol-dependent cytolysin (CDC) from Streptococcus pneumoniae, the main cause for bacterial pneumonia. Liberation of PLY during infection leads to compromised immune system and cytolytic cell death. Here, we repo
Externí odkaz:
https://doaj.org/article/d115b78ddffa4616af6f6aa528f3f42c
Autor:
Umer Bin Abdul Aziz, Ali Saoud, Marcel Bermudez, Maren Mieth, Amira Atef, Thomas Rudolf, Christoph Arkona, Timo Trenkner, Christoph Böttcher, Kai Ludwig, Angelique Hoelzemer, Andreas C. Hocke, Gerhard Wolber, Jörg Rademann
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/a9c589d94a30489c8d0d88a9d47ad5a8
Autor:
Karen Hoffmann, Benedikt Obermayer, Katja Hönzke, Diana Fatykhova, Zeynep Demir, Anna Löwa, Luiz Gustavo Teixeira Alves, Emanuel Wyler, Elena Lopez-Rodriguez, Maren Mieth, Morris Baumgardt, Judith Hoppe, Theresa C. Firsching, Mario Tönnies, Torsten T. Bauer, Stephan Eggeling, Hong-Linh Tran, Paul Schneider, Jens Neudecker, Jens C. Rückert, Achim D. Gruber, Matthias Ochs, Markus Landthaler, Dieter Beule, Norbert Suttorp, Stefan Hippenstiel, Andreas C. Hocke, Mirjana Kessler
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-17 (2022)
The GSK3 inhibitor CHIR99021 is required to maintain the alveolar lineage in alveolar progenitors grown in airway media or AT2 cells become plastic, with the observed effects acting outside of its role as a GSK3B inhibitor.
Externí odkaz:
https://doaj.org/article/04f4581a1d914ad59d4e1d253cb8de1e
Autor:
Morris Baumgardt, Maren Hülsemann, Anna Löwa, Diana Fatykhova, Karen Hoffmann, Mirjana Kessler, Maren Mieth, Katharina Hellwig, Doris Frey, Alina Langenhagen, Anne Voss, Benedikt Obermayer, Emanuel Wyler, Simon Dökel, Achim D Gruber, Ulf Tölch, Stefan Hippenstiel, Andreas C Hocke, Katja Hönzke
Publikováno v:
PLoS ONE, Vol 18, Iss 11, p e0294216 (2023)
[This corrects the article DOI: 10.1371/journal.pone.0276115.].
Externí odkaz:
https://doaj.org/article/27cd70b6b78d49fa83211a11aca3609c
Autor:
Morris Baumgardt, Maren Hülsemann, Anna Löwa, Diana Fatykhova, Karen Hoffmann, Mirjana Kessler, Maren Mieth, Katharina Hellwig, Doris Frey, Alina Langenhagen, Anne Voss, Benedikt Obermayer, Emanuel Wyler, Simon Dökel, Achim D Gruber, Ulf Tölch, Stefan Hippenstiel, Andreas C Hocke, Katja Hönzke
Publikováno v:
PLoS ONE, Vol 17, Iss 12, p e0276115 (2022)
Human-based organ models can provide strong predictive value to investigate the tropism, virulence, and replication kinetics of viral pathogens. Currently, such models have received widespread attention in the study of SARS-CoV-2 causing the COVID-19
Externí odkaz:
https://doaj.org/article/8548fe5158d547d49eb225ae552d3bb8
Autor:
Quach Ngoc Tung, Vu Van Loi, Tobias Busche, Andreas Nerlich, Maren Mieth, Johanna Milse, Jörn Kalinowski, Andreas C. Hocke, Haike Antelmann
Publikováno v:
Redox Biology, Vol 20, Iss , Pp 514-525 (2019)
Mycothiol (MSH) functions as major low molecular weight (LMW) thiol in the industrially important Corynebacterium glutamicum. In this study, we genomically integrated an Mrx1-roGFP2 biosensor in C. glutamicum to measure dynamic changes of the MSH red
Externí odkaz:
https://doaj.org/article/a9f737a49ffd4f44b14c40bd667dcb28
Autor:
Anja Kittel, Fabian Müller, Jörg König, Maren Mieth, Heinrich Sticht, Oliver Zolk, Ana Kralj, Markus R Heinrich, Martin F Fromm, Renke Maas
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e88544 (2014)
Elevated plasma concentrations of asymmetric (ADMA) and symmetric (SDMA) dimethylarginine have repeatedly been linked to adverse clinical outcomes. Both methylarginines are substrates of alanine-glyoxylate aminotransferase 2 (AGXT2). It was the aim o
Externí odkaz:
https://doaj.org/article/0cd03e167a524df2bf191c5634ff32d1
Autor:
Pietro Ravani, Renke Maas, Fabio Malberti, Paola Pecchini, Maren Mieth, Robert Quinn, Giovanni Tripepi, Francesca Mallamaci, Carmine Zoccali
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e72694 (2013)
BACKGROUND AND AIMS: Homoarginine, a precursor of nitric oxide, is an inverse predictor of death in dialysis patients and in subjects with cardiovascular disease and normal kidney function but its relationship with clinical outcomes in chronic kidney
Externí odkaz:
https://doaj.org/article/bdc3a1aedc254df584671fb34d08df85
Autor:
Katja Hönzke, Benedikt Obermayer, Christin Mache, Diana Fatykhova, Mirjana Kessler, Simon Dökel, Emanuel Wyler, Morris Baumgardt, Anna Löwa, Karen Hoffmann, Patrick Graff, Jessica Schulze, Maren Mieth, Katharina Hellwig, Zeynep Demir, Barbara Biere, Linda Brunotte, Angeles Mecate-Zambrano, Judith Bushe, Melanie Dohmen, Christian Hinze, Sefer Elezkurtaj, Mario Tönnies, Torsten T. Bauer, Stephan Eggeling, Hong-Linh Tran, Paul Schneider, Jens Neudecker, Jens C. Rückert, Kai M. Schmidt-Ott, Jonas Busch, Frederick Klauschen, David Horst, Helena Radbruch, Josefine Radke, Frank Heppner, Victor M. Corman, Daniela Niemeyer, Marcel A. Müller, Christine Goffinet, Ronja Mothes, Anna Pascual-Reguant, Anja Erika Hauser, Dieter Beule, Markus Landthaler, Stephan Ludwig, Norbert Suttorp, Martin Witzenrath, Achim D. Gruber, Christian Drosten, Leif-Erik Sander, Thorsten Wolff, Stefan Hippenstiel, Andreas C. Hocke
BackgroundSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) utilises the angiotensin-converting enzyme 2 (ACE2) transmembrane peptidase as cellular entry receptor. However, whether SARS-CoV-2 in the alveolar compartment is strictly ACE2-de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8acfc0972291e89181040408e1f0a61b
http://edoc.mdc-berlin.de/21721/2/21721suppl.pdf
http://edoc.mdc-berlin.de/21721/2/21721suppl.pdf
Autor:
Umer Bin Abdul Aziz, Marcel Bermudez, Maren Mieth, Ali Saoud, Thomas Rudolf, Christoph Arkona, Christoph Böttcher, Kai Ludwig, Andreas Hocke, Gerhard Wolber, Jörg Rademann
Pneumolysin (PLY) is a pore-forming, cholesterol-dependent cytolysin (CDC) from Streptococcus pneumoniae, the main bacterial cause for community-acquired pneumonia. Liberation of PLY during host infection leads to strong immune activation and cytolyt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf770df6fe13660674e9526f10f54b86
https://doi.org/10.26434/chemrxiv-2022-fx0d2
https://doi.org/10.26434/chemrxiv-2022-fx0d2