Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Maren M. Limberg"'
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 3, p 1922 (2024)
The transient receptor potential vanilloid 1 (TRPV1) is a non-selective cation channel expressed on sensory neurons and immune cells. We hypothesize that TRPV1 plays a role in human eosinophil function and is modulated by inflammatory conditions. TRP
Externí odkaz:
https://doaj.org/article/fe2891a5bb0943d6a8e7f6abfa21fdb4
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Basophils are rare cells in the peripheral blood which have the capability to infiltrate into the skin. Invasion of basophils has been detected in pruritic skin diseases, including atopic dermatitis, bullous pemphigoid, chronic spontaneous urticaria
Externí odkaz:
https://doaj.org/article/51c7398c8373498bb14a6fd98ee5f38a
Publikováno v:
Biomolecules, Vol 13, Iss 7, p 1019 (2023)
Bullous pemphigoid (BP) is an autoimmune blistering skin disease, of which the incidence has increased in recent years. BP is characterized by circulating IgG and IgE autoantibodies against the hemidesmosomal proteins BP180 and BP230. Although autoan
Externí odkaz:
https://doaj.org/article/3e987168f7dc4de397724c27d80f4325
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 7, p 6105 (2023)
Allergic diseases are accompanied by a variety of symptoms such as pruritus, coughing, sneezing, and watery eyes, which can result in severe physiological and even psychological impairments. The exact mechanisms of these conditions are not yet comple
Externí odkaz:
https://doaj.org/article/2fefb9290c4c4b1ba712e5f3f31d81b8
Publikováno v:
Biomolecules, Vol 13, Iss 3, p 485 (2023)
Autoimmune bullous skin diseases (AIBDs), such as bullous pemphigoid (BP) and pemphigus, are characterized and caused by autoantibodies targeting structural proteins. In BP, clinical experience and recent systematic evaluation identified pruritus to
Externí odkaz:
https://doaj.org/article/9c0a812ccee648a7abd03cf28e5f48b9
Autor:
Natalie Gray, Maren M. Limberg, Daniela Wiebe, Tobias Weihrauch, Anna Langner, Nicola Brandt, Anja U. Bräuer, Ulrike Raap
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 24, p 16117 (2022)
Basophils are key effector cells in atopic diseases, and the signaling sphingolipid Sphigosine-1-phosphate (S1P) is emerging as an important mediator in these conditions. The possible interaction of S1P and basophils and the resulting biological effe
Externí odkaz:
https://doaj.org/article/13ca43b7c4e74b0491af2936fd18f78d
Autor:
Aylin Ruppenstein, Maren M. Limberg, Karin Loser, Andreas E. Kremer, Bernhard Homey, Ulrike Raap
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
Pruritus is a common, but very challenging symptom with a wide diversity of underlying causes like dermatological, systemic, neurological and psychiatric diseases. In dermatology, pruritus is the most frequent symptom both in its acute and chronic fo
Externí odkaz:
https://doaj.org/article/28d87b33bf1e472986a8253dc32d77a3
Autor:
Aylin, Ruppenstein, Maren M, Limberg, Karin, Loser, Andreas E, Kremer, Bernhard, Homey, Ulrike, Raap
Publikováno v:
Frontiers in Medicine
Pruritus is a common, but very challenging symptom with a wide diversity of underlying causes like dermatological, systemic, neurological and psychiatric diseases. In dermatology, pruritus is the most frequent symptom both in its acute and chronic fo
Autor:
Maren M. Limberg, Niels Decher, Jürgen Daut, Kai Siebert, Stefan Kling, Vijay Renigunta, Xinle Zou, Marylou Zuzarte, Susanne Rinné, Thomas Fischer, Günter Schlichthörl
Publikováno v:
Molecular Biology of the Cell
SNARE proteins can have functions unrelated to membrane fusion. The unassembled form of the SNARE protein syntaxin-8 interacts with the K+ channel TASK-1; both proteins are internalized via clathrin-mediated endocytosis in a cooperative manner. This
Autor:
Birgit Stallmeyer, Michael F. Netter, Niels Decher, Eric Schulze-Bahr, Sven Zumhagen, Andrew A. Grace, Susanne Rinné, Alison J. Coffey, Doris Böckelmann, Jane Rogers, Maren M. Limberg
Publikováno v:
Basic Research in Cardiology. 108
Andersen-Tawil syndrome (ATS) is characterized by dysmorphic features, periodic paralyses and abnormal ventricular repolarization. After genotyping a large set of patients with congenital long-QT syndrome, we identified two novel, heterozygous KCNJ2