Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Maren Lindner"'
Autor:
Daniel Schiffmann, Victoria Lampkemeyer, Maren Lindner, Ann-Katrin Fleck, Kathrin Koch, Melanie Eschborn, Marie Liebmann, Jan-Kolja Strecker, Jens Minnerup, Heinz Wiendl, Luisa Klotz
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 21, p 15798 (2023)
Multiple sclerosis (MS) is a chronic inflammatory autoimmune disease causing axonal degeneration and demyelination. Exercise in mice with active monophasic experimental autoimmune encephalomyelitis (EAE) attenuates disease severity associated with di
Externí odkaz:
https://doaj.org/article/c068d9a7c46049fab23d35d4faf9a040
Autor:
Katja Thümmler, Eran Rom, Thomas Zeis, Maren Lindner, Sarah Brunner, John J. Cole, Diana Arseni, Steve Mücklisch, Julia M. Edgar, Nicole Schaeren-Wiemers, Avner Yayon, Christopher Linington
Publikováno v:
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-15 (2019)
Abstract Fibroblast growth factor (FGF) signaling contributes to failure of remyelination in multiple sclerosis, but targeting this therapeutically is complicated by its functional pleiotropy. We now identify FGF2 as a factor up-regulated by astrocyt
Externí odkaz:
https://doaj.org/article/7ee1fa64b1394a10aeb801926f69e36f
Autor:
Kathrin Koch, Maren Lindner, Ann-Katrin Fleck, Marie Liebmann, Melanie Eschborn, Lisa Zondler, Rodrigo Diéguez-Hurtado, Ralf H. Adams, Gerd Meyer zu Hörste, Alexander Zarbock, Tanja Kuhlmann, Heinz Wiendl, Luisa Klotz
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 21, p 13081 (2022)
Pericytes at the blood–brain barrier (BBB) are located between the tight endothelial cell layer of the blood vessels and astrocytic endfeet. They contribute to central nervous system (CNS) homeostasis by regulating BBB development and maintenance.
Externí odkaz:
https://doaj.org/article/9eb3bee76976410d8a417b45a429a70e
Autor:
Sonja Hochmeister, Thomas Pekar, Maren Lindner, Maja Kitic, Michaela Haindl, Maria Storch, Franz Fazekas, Christopher Linington
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e85393 (2014)
UnlabelledNeurofascin was recently reported as a target for axopathic autoantibodies in patients with multiple sclerosis (MS), a response that will exacerbate axonal pathology and disease severity in an animal model of multiple sclerosis. As transpla
Externí odkaz:
https://doaj.org/article/a25ee93f6e494efe8db53d8e25ee8830
Autor:
Maren Lindner, Tobias Bopp, Stefanie Bock, Steffen Pfeuffer, Felix Luessi, Sven G. Meuth, Jochen Huehn, Thomas Pap, Marc Pawlitzki, Stefan Bittner, Marie Liebmann, Paul Marciniak, Leoni Rolfes, Stjepana Kovac, Johannes Roth, Gerd Meyer zu Hörste, Nils Opel, Patricia Seja, Derya Cengiz, Alexander M Herrmann, Achmet Imam Chasan, Stefan Floess, Tim Hahn, Luisa Klotz, Tobias Marschall, Björn Tackenberg, Erhard Wischmeyer, Thomas Budde, Julian A. Schreiber, Udo Dannlowski, Bernhard Wünsch, Tanja Kuhlmann, Christina B Schroeter, Heinz Wiendl, Tobias Ruck, Frank Döring, Guiscard Seebohm, Lukas Gola
Publikováno v:
Cell Research
It remains largely unclear how thymocytes translate relative differences in T cell receptor (TCR) signal strength into distinct developmental programs that drive the cell fate decisions towards conventional (Tconv) or regulatory T cells (Treg). Follo
Autor:
Claudia Janoschka, Maren Lindner, Nils Koppers, Laura Starost, Marie Liebmann, Melanie Eschborn, Tilman Schneider-Hohendorf, Farina Windener, David Schafflick, Ann-Katrin Fleck, Kathrin Koch, Marie Deffner, Anna-Sophie Schwarze, Andreas Schulte-Mecklenbeck, Imke Metz, Sven G. Meuth, Catharina C. Gross, Gerd Meyer zu Hörste, Nicholas Schwab, Tanja Kuhlmann, Heinz Wiendl, Monika Stoll, Luisa Klotz
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 120(1)
After natalizumab (NAT) cessation, some multiple sclerosis (MS) patients experience a severe disease rebound. The rebound pathophysiology is still unclear; however, it has been linked to interleukin-17-producing T-helper (Th17) cells. We demonstrate
Autor:
Klotz, Kathrin Koch, Maren Lindner, Ann-Katrin Fleck, Marie Liebmann, Melanie Eschborn, Lisa Zondler, Rodrigo Diéguez-Hurtado, Ralf H. Adams, Gerd Meyer zu Hörste, Alexander Zarbock, Tanja Kuhlmann, Heinz Wiendl, Luisa
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 21; Pages: 13081
Pericytes at the blood–brain barrier (BBB) are located between the tight endothelial cell layer of the blood vessels and astrocytic endfeet. They contribute to central nervous system (CNS) homeostasis by regulating BBB development and maintenance.
Publikováno v:
Neuromethods ISBN: 9781071612125
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4ee673152fb38a16cad4ae77d106565
https://doi.org/10.1007/978-1-0716-1213-2_8
https://doi.org/10.1007/978-1-0716-1213-2_8
Alemtuzumab-induced immune phenotype and repertoire changes: implications for secondary autoimmunity
Autor:
Tobias Ruck, Sumanta Barman, Andreas Schulte-Mecklenbeck, Steffen Pfeuffer, Falk Steffen, Christopher Nelke, Christina B. Schroeter, Alice Willison, Michael Heming, Thomas Müntefering, Nico Melzer, Julia Krämer, Maren Lindner, Marianne Riepenhausen, Catharina C. Gross, Luisa Klotz, Stefan Bittner, Paolo A. Muraro, Tilman Schneider-Hohendorf, Nicholas Schwab, Gerd Meyer zu Hörste, Norbert Goebels, Sven G. Meuth, Heinz Wiendl
Publikováno v:
Brain : a journal of neurology. 145(5)
Alemtuzumab is a monoclonal antibody that causes rapid depletion of CD52-expressing immune cells. It has proven to be highly efficacious in active relapsing–remitting multiple sclerosis; however, the high risk of secondary autoimmune disorders has
Autor:
Hans R. Schöler, Francesca Ruffini, Christian Thomas, Maren Lindner, Albrecht Röpke, Yu Kang T. Xu, Jürgen Winkler, Katharina Heß, Jack P. Antel, Gianvito Martino, Laura Starost, Martin Stehling, Hannes C.A. Drexler, Linda Ottoboni, Luisa Klotz, Marc Ehrlich, Martin Herold, Tanja Kuhlmann
Publikováno v:
Acta Neuropathologica
Multiple sclerosis (MS) is the most frequent demyelinating disease in young adults and despite significant advances in immunotherapy, disease progression still cannot be prevented. Promotion of remyelination, an endogenous repair mechanism resulting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e9f91d4a45a12bbcea369738e29e074