Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Maren Diepenbruck"'
Autor:
Gaetana Restivo, Aizhan Tastanova, Zsolt Balázs, Federica Panebianco, Maren Diepenbruck, Caner Ercan, Bodgan-T. Preca, Jürg Hafner, Walter P. Weber, Christian Kurzeder, Marcus Vetter, Simone Münst Soysal, Christian Beisel, Mohamed Bentires-Alj, Salvatore Piscuoglio, Michael Krauthammer, Mitchell P. Levesque
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-12 (2022)
Fresh vs. slow-frozen tissues from various malignancies are compared for the establishment of 2D, 3D and ex vivo cultures, as well as for scRNAseq analysis, and found to be comparable and suitable for cancer research.
Externí odkaz:
https://doaj.org/article/87d96e9a64c244768ec47752d441b0e3
Autor:
Daniela A. Ferraro, Francesca Patella, Sara Zanivan, Cinzia Donato, Nicola Aceto, Monica Giannotta, Elisabetta Dejana, Maren Diepenbruck, Gerhard Christofori, Martin Buess
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-13 (2019)
Abstract Background The tumour microenvironment is a critical regulator of malignant cancer progression. While endothelial cells have been widely studied in the context of tumour angiogenesis, their role as modulators of cancer cell invasion and migr
Externí odkaz:
https://doaj.org/article/d0db17bd31394cb094787352d975e11f
Autor:
Maren Diepenbruck, Stefanie Tiede, Meera Saxena, Robert Ivanek, Ravi Kiran Reddy Kalathur, Fabiana Lüönd, Nathalie Meyer-Schaller, Gerhard Christofori
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
miRNAs have been involved in tumour development and progression. Here the authors uncover a double feedback loop between miR-1199-5p and the Zeb1, potentially coordinating a protein involved in epithelial mesenchymal transition and tumour metastasis.
Externí odkaz:
https://doaj.org/article/30db2a3701054bcb82fae40e87e50062
Autor:
Maren Diepenbruck, Gerhard Christofori
Publikováno v:
Cell Stress, Vol 1, Iss 3, Pp 139-140 (2017)
Epithelial to mesenchymal transition (EMT) as well as its reversal process, mesenchymal to epithelial transition (MET), are essential and well-controlled cellular processes during embryonic development. Tightly controlled regulatory mechanisms guide
Externí odkaz:
https://doaj.org/article/a6a86d7f41b54dfa9171d87e5cde07ef
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e48651 (2012)
IntroductionIncreasing evidence supports a role of an epithelial to mesenchymal transition (EMT) process in endowing subsets of tumor cells with properties driving malignant tumor progression and resistance to cancer therapy. To advance our understan
Externí odkaz:
https://doaj.org/article/bd1da152b8244402af51e446f2e33a11
Autor:
Milica Vulin, Charly Jehanno, Atul Sethi, Ana Luísa Correia, Milan M. S. Obradović, Joana Pinto Couto, Marie-May Coissieux, Maren Diepenbruck, Bogdan-Tiberius Preca, Katrin Volkmann, Priska Auf der Maur, Alexander Schmidt, Simone Münst, Loïc Sauteur, Michal Kloc, Marta Palafox, Adrian Britschgi, Vincent Unterreiner, Olaf Galuba, Isabelle Claerr, Sandra Lopez-Romero, Giorgio G. Galli, Daniel Baeschlin, Ryoko Okamoto, Savas D. Soysal, Robert Mechera, Walter P. Weber, Thomas Radimerski, Mohamed Bentires-Alj
Publikováno v:
Oncogene. 41:4459-4473
Plasticity delineates cancer subtypes with more or less favourable outcomes. In breast cancer, the subtype triple-negative lacks expression of major differentiation markers, e.g., estrogen receptor α (ERα), and its high cellular plasticity results
Autor:
Gerhard Christofori, Stefanie Tiede, Maren Diepenbruck, Robert Ivanek, Nathalie Meyer-Schaller
Publikováno v:
Oncogene. 39:4728-4740
An epithelial to mesenchymal transition (EMT) is an embryonic dedifferentiation program which is aberrantly activated in cancer cells to acquire cellular plasticity. This plasticity increases the ability of breast cancer cells to invade into surround
Autor:
Gerhard Christofori, Ravi Kiran Reddy Kalathur, Mizue Hisano, Salvatore Risoli, Robert Ivanek, Maren Diepenbruck, Meera Saxena, Melanie Neutzner, Thomas R. Bürglin, Kirti Sharma
Publikováno v:
Journal of cell science. 134(21)
The vast majority of breast cancer-associated deaths are due to metastatic spread of cancer cells, a process aided by epithelial-to-mesenchymal transition (EMT). Mounting evidence has indicated that long non-coding RNAs (lncRNAs) also contribute to t
Autor:
Nathalie, Meyer-Schaller, Stefanie, Tiede, Robert, Ivanek, Maren, Diepenbruck, Gerhard, Christofori
Publikováno v:
Oncogene. 39(24)
An epithelial to mesenchymal transition (EMT) is an embryonic dedifferentiation program which is aberrantly activated in cancer cells to acquire cellular plasticity. This plasticity increases the ability of breast cancer cells to invade into surround
Autor:
Nathalie Meyer-Schaller, Maren Diepenbruck, Simona Pavan, Meera Saxena, Ravi Kiran Reddy Kalathur, Gerhard Christofori
Publikováno v:
Oncogene. 37:4197-4213
An epithelial to mesenchymal transition (EMT) has been correlated to malignant tumor progression and metastasis by promoting cancer cell migration and invasion and chemoresistance. Hence, finding druggable EMT effectors is critical to efficiently int