Effects of dosage in new users of lamotrigine inducing epidermal necrolysis: Results of the German Registry of Severe Skin Reactions

Autor: Sophie Diederich, Ulrich Hemmeter, Maren Paulmann, Maja Mockenhaupt

Publikováno v: Epilepsia. 64:1259-1265

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c365b9cac965dbd121135602b26171e8
https://doi.org/10.1111/epi.17563

Epidermal necrolysis in the context of immuno‐oncologic medication as well as kinase inhibitors and biologics

Autor: Mirjana, Ziemer, Viviane, Fries, Maren, Paulmann, Maja, Mockenhaupt

Publikováno v: JDDG: Journal der Deutschen Dermatologischen Gesellschaft. 20:777-786

Stevens-Johnson syndrome and toxic epidermal necrolysis are severe, primarily drug-induced reactions of skin and mucosa. Since they differ in the extent of skin detachment but not in etiology, they are grouped together as epidermal necrolysis (EN). D

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::358400fd540c1521f9fd0b6389bd3459
https://doi.org/10.1111/ddg.14711

Severe skin reactions: clinical picture, epidemiology, etiology, pathogenesis, and treatment

Autor: Maja Mockenhaupt, Maren Paulmann

Publikováno v: Allergo Journal International. 28:311-326

Severe skin reactions, mostly following medication use, are rare and can be associated with high mortality. A suitable treatment approach that is able to reduce mortality is needed. Recent publications on this topic were reviewed and evaluated. In th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f6921f0e412f2b2938d6fa713f67fac8
https://doi.org/10.1007/s40629-019-00111-8

Loss-of-function myeloperoxidase mutations are associated with increased neutrophil counts and pustular skin disease

Autor: Marta Vergnano, Maja Mockenhaupt, Natashia Benzian-Olsson, Maren Paulmann, Katarzyna Grys, Satveer K. Mahil, Charlotte Chaloner, Ines A. Barbosa, Suzannah August, A. David Burden, Siew-Eng Choon, Hywel Cooper, Alex A. Navarini, Nick J. Reynolds, Shyamal Wahie, Richard B. Warren, Andrew Wright, Ulrike Huffmeier, Patrick Baum, Sudha Visvanathan, Jonathan N. Barker, Catherine H. Smith, Francesca Capon, Thamir Abraham, Mahmud Ali, David Baudry, Anthony Bewley, Christopher E.M. Griffiths, John Ingram, Susan Kelly, Mohsen Korshid, Effie Ladoyanni, John McKenna, Freya Meynell, Richard Parslew, Prakash Patel, Angela Pushparajah, Nick Reynolds, Catherine Smith, Richard Warren

Publikováno v: Hueffmeier, U, Baum, P, Visvanathan, S & Barker, J N & Smith, C H 2020, ' Loss-of-function myeloperoxidase mutations are associated with increased neutrophil counts and pustular skin disease ', American Journal of Human Genetics, vol. 107, no. 3, pp. 539-543 . https://doi.org/10.1016/j.ajhg.2020.06.020
APRICOT and PLUM study team 2020, ' Loss-of-Function Myeloperoxidase Mutations Are Associated with Increased Neutrophil Counts and Pustular Skin Disease ', American Journal of Human Genetics . https://doi.org/10.1016/j.ajhg.2020.06.020
American Journal of Human Genetics

The identification of disease alleles underlying human autoinflammatory diseases can provide important insights into the mechanisms that maintain neutrophil homeostasis. Here, we focused our attention on generalized pustular psoriasis (GPP), a potent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::393991be26bba806e91f9482c1f48e5f
https://doi.org/10.1016/j.ajhg.2021.03.001

Schwere arzneimittelinduzierte Hautreaktionen: Klinik, Diagnostik, Ätiologie und Therapie

Autor: Maren Paulmann, Maja Mockenhaupt

Publikováno v: JDDG: Journal der Deutschen Dermatologischen Gesellschaft. 13:625-645

Zusammenfassung Arzneimittel konnen schwere Hautreaktionen auslosen, deren Reaktionsformen sich im klinischen Bild, in der Prognose und der Therapie unterscheiden. Neben Stevens-Johnson-Syndrom (SJS), toxisch epidermaler Nekrolyse (TEN) und generalis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::215c2f2e50a73e82015855c3cfe84cfd
https://doi.org/10.1111/ddg.130_12747