Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Marella Maroder"'
Autor:
Sonia Coni, Silvia Maria Serrao, Zuleyha Nihan Yurtsever, Laura Di Magno, Rosa Bordone, Camilla Bertani, Valerio Licursi, Zaira Ianniello, Paola Infante, Marta Moretti, Marialaura Petroni, Francesca Guerrieri, Alessandro Fatica, Alberto Macone, Enrico De Smaele, Lucia Di Marcotullio, Giuseppe Giannini, Marella Maroder, Enzo Agostinelli, Gianluca Canettieri
Publikováno v:
Cell Death and Disease, Vol 11, Iss 12, Pp 1-14 (2020)
ABSTRACT Eukaryotic Translation Initiation Factor 5A (EIF5A) is a translation factor regulated by hypusination, a unique posttranslational modification catalyzed by deoxyhypusine synthetase (DHPS) and deoxyhypusine hydroxylase (DOHH) starting from th
Externí odkaz:
https://doaj.org/article/fdcfae0429de479c97a55c2c58a84f8e
Autor:
Diletta Overi, Guido Carpino, Marta Moretti, Antonio Franchitto, Lorenzo Nevi, Paolo Onori, Enrico De Smaele, Luca Federici, Daniele Santorelli, Marella Maroder, Lola M. Reid, Vincenzo Cardinale, Domenico Alvaro, Eugenio Gaudio
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Contrasting evidence is present regarding the contribution of stem/progenitor cell populations to pancreatic regeneration in diabetes. Interestingly, a cell compartment with stem/progenitor cell features has been identified in the pancreatic duct gla
Externí odkaz:
https://doaj.org/article/2a9e9e709c494cdd99e6d18926f6d091
Autor:
Laura Di Magno, Simona Manni, Fiorella Di Pastena, Sonia Coni, Alberto Macone, Sara Cairoli, Manolo Sambucci, Paola Infante, Marta Moretti, Marialaura Petroni, Carmine Nicoletti, Carlo Capalbo, Enrico De Smaele, Lucia Di Marcotullio, Giuseppe Giannini, Luca Battistini, Bianca Maria Goffredo, Egidio Iorio, Enzo Agostinelli, Marella Maroder, Gianluca Canettieri
Publikováno v:
Cell Reports, Vol 30, Iss 6, Pp 1735-1752.e7 (2020)
Summary: The antidiabetic drug phenformin displays potent anticancer activity in different tumors, but its mechanism of action remains elusive. Using Shh medulloblastoma as model, we show here that at clinically relevant concentrations, phenformin el
Externí odkaz:
https://doaj.org/article/598bceb7f2be4008945d9487d0404b2f
Autor:
Paola Infante, Roberta Faedda, Flavia Bernardi, Francesca Bufalieri, Ludovica Lospinoso Severini, Romina Alfonsi, Daniela Mazzà, Mariangela Siler, Sonia Coni, Agnese Po, Marialaura Petroni, Elisabetta Ferretti, Mattia Mori, Enrico De Smaele, Gianluca Canettieri, Carlo Capalbo, Marella Maroder, Isabella Screpanti, Marcel Kool, Stefan M. Pfister, Daniele Guardavaccaro, Alberto Gulino, Lucia Di Marcotullio
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
SuFu is a tumour suppressor in medulloblastoma and regulates Gli proteins in the Sonic Hedgehog pathway; however, the molecular mechanisms behind this regulation are unclear. Here, the authors show that the Itch/β-arrestin2 complex binds and ubiquit
Externí odkaz:
https://doaj.org/article/f7f69de80acf45bbb0fc69f6b60924c1
Autor:
Enrico De Smaele, Lucia Di Marcotullio, Marta Moretti, Marianna Pelloni, Maria Anna Occhione, Paola Infante, Danilo Cucchi, Azzura Greco, Laura Pietrosanti, Jelena Todorovic, Sonia Coni, Gianluca Canettieri, Elisabetta Ferretti, Roberto Bei, Marella Maroder, Isabella Screpanti, Alberto Gulino
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 13, Iss 4, Pp 374-385 (2011)
Medulloblastoma is the most common pediatric malignant brain tumor, arising from aberrant cerebellar precursors' development, a process mainly controlled by Hedgehog (Hh) signaling pathway. Histone deacetylase HDAC1 has been recently shown to modulat
Externí odkaz:
https://doaj.org/article/3c47502b291a4528a149ac9a248b7d27
Autor:
Enrico De Smaele, Caterina Fragomeli, Elisabetta Ferretti, Marianna Pelloni, Agnese Po, Gianluca Canettieri, Sonia Coni, Lucia Di Marcotullio, Azzura Greco, Marta Moretti, Concezio Di Rocco, Simona Pazzaglia, Marella Maroder, Isabella Screpanti, Giuseppe Giannini, Alberto Gulino
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 10, Iss 1, Pp 89-98 (2008)
Medulloblastoma (MB) is the most common malignant brain tumor of childhood arising from deregulated cerebellar development. Sonic Hedgehog (Shh) pathway plays a critical role in cerebellar development and its aberrant expression has been identified i
Externí odkaz:
https://doaj.org/article/1e2bf33c12544e118836d04060380923
Autor:
Vincenzo Cardinale, Rosa Puca, Guido Carpino, Gaia Scafetta, Anastasia Renzi, Michele De Canio, Francesca Sicilia, Lorenzo Nevi, Domenico Casa, Rocco Panetta, Pasquale Bartolomeo Berloco, Lola M Reid, Giorgio Federici, Eugenio Gaudio, Marella Maroder, Domenico Alvaro
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0134677 (2015)
Generation of β-pancreatic cells represents a major goal in research. The aim of this study was to explore a protein-based strategy to induce differentiation of human biliary tree stem cells (hBTSCs) towards β-pancreatic cells. A plasmid containing
Externí odkaz:
https://doaj.org/article/7a4f67623566411395e4e350b0c0cbc1
Autor:
Donatella Ponti, Gian Carlo Bellenchi, Rosa Puca, Daniela Bastianelli, Marella Maroder, Giuseppe Ragona, Pascal Roussel, Marc Thiry, Dan Mercola, Antonella Calogero
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e96037 (2014)
EGR1 is an immediate early gene with a wide range of activities as transcription factor, spanning from regulation of cell growth to differentiation. Numerous studies show that EGR1 either promotes the proliferation of stimulated cells or suppresses t
Externí odkaz:
https://doaj.org/article/02d9463e55d64237a30a0320ecbbcf4d
Autor:
Sonia Coni, Rosa Bordone, Devon Michael Ivy, Zuleyha Nihan Yurtsever, Laura Di Magno, Rodrigo D'Amico, Bianca Cesaro, Alessandro Fatica, Francesca Belardinilli, Francesca Bufalieri, Marella Maroder, Enrico De Smaele, Lucia Di Marcotullio, Giuseppe Giannini, Enzo Agostinelli, Gianluca Canettieri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb5d24f1d7f3dc2802e8a04f34408998
https://hdl.handle.net/11573/1674490
https://hdl.handle.net/11573/1674490
Autor:
Marta Moretti, Laura Di Magno, Francesca Guerrieri, Valerio Licursi, Lucia Di Marcotullio, Silvia Maria Serrao, Enzo Agostinelli, Zuleyha Nihan Yurtsever, Sonia Coni, Rosa Bordone, Camilla Bertani, Zaira Ianniello, Marella Maroder, Giuseppe Giannini, Alberto Macone, Paola Infante, Alessandro Fatica, Gianluca Canettieri, Enrico De Smaele, Marialaura Petroni
Publikováno v:
Cell Death and Disease, Vol 11, Iss 12, Pp 1-14 (2020)
Cell Death & Disease
Cell Death & Disease
Eukaryotic Translation Initiation Factor 5A (EIF5A) is a translation factor regulated by hypusination, a unique posttranslational modification catalyzed by deoxyhypusine synthetase (DHPS) and deoxyhypusine hydroxylase (DOHH) starting from the polyami