Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Mareli, Allmeroth"'
Autor:
Elisabeth Eppard, Ana de la Fuente, Nicole Mohr, Mareli Allmeroth, Rudolf Zentel, Matthias Miederer, Stefanie Pektor, Frank Rösch
Publikováno v:
EJNMMI Research, Vol 8, Iss 1, Pp 1-14 (2018)
Abstract Background In this work, the in vitro and in vivo stabilities and the pharmacology of HPMA-made homopolymers were studied by means of radiometal-labeled derivatives. Aiming to identify the fewer amount and the optimal DOTA-linker structure t
Externí odkaz:
https://doaj.org/article/d2fa3e625d174a858aa6f3bfbe074e77
Autor:
Nicole Bausbacher, Karolin Wagener, Dorothea Moderegger, Frank Rösch, Stefan Kramer, Oliver Thews, Barbara Biesalski, Rudolf Zentel, Mareli Allmeroth, Achim T. Reibel
Publikováno v:
Nuclear Medicine and Biology. 58:59-66
Background For the evaluation of macromolecular drug delivery systems suitable pre-clinical monitoring of potential nanocarrier systems is needed. In this regard, both short-term as well as long-term in vivo tracking is crucial to understand structur
Publikováno v:
International Journal of Nanomedicine
Daniel Gündel,1 Mareli Allmeroth,2 Sarah Reime,1 Rudolf Zentel,2 Oliver Thews1 1Institute of Physiology, Martin Luther University Halle-Wittenberg, Halle (Saale), 2Institute of Organic Chemistry, Johannes Gutenberg-University, Mainz, Germany Backgro
Autor:
Karolin, Wagener, Dorothea, Moderegger, Mareli, Allmeroth, Achim, Reibel, Stefan, Kramer, Barbara, Biesalski, Nicole, Bausbacher, Rudolf, Zentel, Oliver, Thews, Frank, Rösch
Publikováno v:
Nuclear medicine and biology. 58
For the evaluation of macromolecular drug delivery systems suitable pre-clinical monitoring of potential nanocarrier systems is needed. In this regard, both short-term as well as long-term in vivo tracking is crucial to understand structure-property
Autor:
Mirjam Hemmelmann, Kaloian Koynov, Rudolf Zentel, Matthias Barz, Mareli Allmeroth, Christiane Knoth, Frank Rösch, Dorothea Moderegger, Ulrich Schmitt, Christoph Hiemke
Publikováno v:
Macromolecular Rapid Communications. 32:712-717
In this study we give evidence that domperidone encapsulated into amphiphilic p(HPMA)-co-p(laurylmethacrylate) (LMA) copolymer aggregates is able to cross the blood-brain barrier, since it affected motor behaviour in animals, which is a sensitive mea
Publikováno v:
Biochemistry. 53(9)
Because a polymer environment might be milder than a detergent micelle, amphiphilic polymers have attracted attention as alternatives to detergents in membrane biochemistry. The polymer poly[N-(2-hydroxypropyl)-methacrylamid] [p(HPMA)] has recently b
Autor:
Oliver Thews, Mareli Allmeroth, Daniel Gündel, Dorothea Moderegger, Kristin Mohr, Kaloian Koynov, Hans-Georg Buchholz, Rudolf Zentel, Frank Rösch
Publikováno v:
Biomacromolecules. 14(9)
Polymeric drug carriers aim to selectively target tumors in combination with protecting normal tissue. In this regard polymer structure and molecular weight are key factors considering organ distribution and tumor accumulation of the polymeric drug d
Autor:
Dorothea Moderegger, Nicole Mohr, Oliver Thews, Kaloian Koynov, Daniel Gündel, Hans-Georg Buchholz, Mareli Allmeroth, Rudolf Zentel, Frank Rösch
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 172(1)
This paper reports the body distribution of block copolymers (made by controlled radical polymerization) with N-(2-hydroxypropyl)methacrylamide (HPMA) as hydrophilic block and lauryl methacrylate (LMA) as hydrophobic block. They form micellar aggrega
Modifying the body distribution of HPMA-based copolymers by molecular weight and aggregate formation
Autor:
Dorothea Moderegger, Barbara Biesalski, Mareli Allmeroth, Oliver Thews, Rudolf Zentel, Frank Rösch, Kaloian Koynov
Publikováno v:
Biomacromolecules. 12(7)
There is a recognized need to create well-defined polymer probes for in vivo and clinical positron emission tomography (PET) imaging to guide the development of new generation polymer therapeutics. Using the RAFT polymerization technique in combinati
Autor:
Ulrich Schmitt, Mareli Allmeroth, Dorothea Moderegger, Christiane Knoth, Kaloian Koynov, Matthias Barz, Rudolf Zentel, Frank Rösch, Mirjam Hemmelmann, Christoph Hiemke
Publikováno v:
Macromolecular Rapid Communications. 32