Zobrazeno 1 - 10
of 105
pro vyhledávání: '"Marek Wieczorek"'
Autor:
Paweł Piatek, Magdalena Namiecinska, Natalia Lewkowicz, Małgorzata Kulińska-Michalska, Zbigniew Jabłonowski, Mariola Matysiak, Sylwia Michlewska, Marek Wieczorek, Przemysław Lewkowicz
Publikováno v:
Journal of Inflammation, Vol 21, Iss 1, Pp 1-23 (2024)
Abstract Background Neutrophils are a heterogeneous population capable of antimicrobial functions associated with pre-activation/activation and tissue regeneration. The specific polarisation of immune cells is mediated by the modification of ‘chrom
Externí odkaz:
https://doaj.org/article/5390482dcc3344d1a020bdcdb6077167
Autor:
Paweł Piatek, Natalia Lewkowicz, Sylwia Michlewska, Marek Wieczorek, Radosław Bonikowski, Karol Parchem, Przemysław Lewkowicz, Magdalena Namiecinska
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The blood–brain barrier (BBB) tightly controls the microenvironment of the central nervous system (CNS) to allow neurons to function properly. Additionally, emerging studies point to the beneficial effect of natural oils affecting a wide variety of
Externí odkaz:
https://doaj.org/article/0d58fd63aab547259c33605604594638
Autor:
Anna Teresa Kobrzycka, Adrian Mateusz Stankiewicz, Joanna Goscik, Monika Gora, Beata Burzynska, Roksana Iwanicka-Nowicka, Krystyna Pierzchala-Koziec, Marek Wieczorek
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 16 (2022)
BackgroundVagus nerve is one of the crucial routes in communication between the immune and central nervous systems. The impaired vagal nerve function may intensify peripheral inflammatory processes. This effect subsides along with prolonged recovery
Externí odkaz:
https://doaj.org/article/2f799512b51f46ea97bb377562abadc3
Autor:
Paweł Piatek, Magdalena Namiecinska, Natalia Lewkowicz, Małgorzata Kulińska-Michalska, Zbigniew Jabłonowski, Mariola Matysiak, Justyna Dulska, Sylwia Michlewska, Marek Wieczorek, Przemysław Lewkowicz
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Neutrophils are a heterogenous population capable of both antimicrobial functions and suppressor ones, however, no specific pattern of transcription factors controlling this plasticity has been identified. We observed rapid changes in the neutrophil
Externí odkaz:
https://doaj.org/article/69771c17f4cd4e4cbf8f8ccb4503331d
Autor:
Dorota Łażewska, Agata Siwek, Agnieszka Olejarz-Maciej, Agata Doroz-Płonka, Anna Wiktorowska-Owczarek, Marta Jóźwiak-Bębenista, David Reiner-Link, Annika Frank, Wioletta Sromek-Trzaskowska, Ewelina Honkisz-Orzechowska, Ewelina Królicka, Holger Stark, Marek Wieczorek, Waldemar Wagner, Katarzyna Kieć-Kononowicz, Anna Stasiak
Publikováno v:
Pharmaceutics, Vol 14, Iss 10, p 2187 (2022)
The clinical symptoms of Parkinson’s disease (PD) appear when dopamine (DA) concentrations in the striatum drops to around 20%. Simultaneous inhibitory effects on histamine H3 receptor (H3R) and MAO B can increase DA levels in the brain. A series o
Externí odkaz:
https://doaj.org/article/9d182e4dcb5d4290bc05ad6a476c576a
Autor:
Paweł Piatek, Maciej Tarkowski, Magdalena Namiecinska, Agostino Riva, Marek Wieczorek, Sylwia Michlewska, Justyna Dulska, Małgorzata Domowicz, Małgorzata Kulińska-Michalska, Natalia Lewkowicz, Przemysław Lewkowicz
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Peripheral neutrophils in HIV-infected individuals are characterized by impairment of chemotaxis, phagocytosis, bactericidal activity, and oxidative burst ability regardless of whether patients are receiving antiretroviral therapy or not. Neutrophil
Externí odkaz:
https://doaj.org/article/539a9c3e5136423ba3e89aff0fa95b87
Autor:
Anna Kobrzycka, Paweł Napora, Brandon L. Pearson, Krystyna Pierzchała-Koziec, Rafał Szewczyk, Marek Wieczorek
Publikováno v:
Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-18 (2019)
Abstract Background Determining the etiology and possible treatment strategies for numerous diseases requires a comprehensive understanding of compensatory mechanisms in physiological systems. The vagus nerve acts as a key interface between the brain
Externí odkaz:
https://doaj.org/article/b34a9bbbcdec4936b1d839407675409c
Autor:
Paweł Jóźwiak, Piotr Ciesielski, Agnieszka Zaczek, Anna Lipińska, Lech Pomorski, Marek Wieczorek, Magdalena Bryś, Ewa Forma, Anna Krześlak
Publikováno v:
Journal of Biomedical Science, Vol 24, Iss 1, Pp 1-10 (2017)
Abstract Background Cells adapt to hypoxia by transcriptional induction of genes that participate in regulation of angiogenesis, glucose metabolism and cell proliferation. The primary factors mediating cell response to low oxygen tension are hypoxia
Externí odkaz:
https://doaj.org/article/ae2a7442738c44cca65368d028fbc820
Autor:
Marek Wieczorek, Jana Sticht, Sebastian Stolzenberg, Sebastian Günther, Christoph Wehmeyer, Zeina El Habre, Miguel Álvaro-Benito, Frank Noé, Christian Freund
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
MHCII proteins bind and present both foreign and self-antigens to potentially activate CD4+ T cells via cognate T cell receptors (TCRs) during the adaptive immune response. Here, the authors combine NMR-detected H/D exchange with Markov modelling ana
Externí odkaz:
https://doaj.org/article/885b930885fb44358b5880c82938cbe4
Autor:
Katharina Koschek, Vedat Durmaz, Oxana Krylova, Marek Wieczorek, Shilpi Gupta, Martin Richter, Alexander Bujotzek, Christina Fischer, Rainer Haag, Christian Freund, Marcus Weber, Jörg Rademann
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 11, Iss 1, Pp 837-847 (2015)
Three polymers, poly(N-(2-hydroxypropyl)methacrylamide) (pHPMA), hyperbranched polyglycerol (hPG), and dextran were investigated as carriers for multivalent ligands targeting the adaptive tandem WW-domain of formin-binding protein (FBP21). Polymer ca
Externí odkaz:
https://doaj.org/article/c374aa3a28494ccc9e4db5c0b9399341