Zobrazeno 1 - 10
of 157
pro vyhledávání: '"Marek Wesolowski"'
Publikováno v:
Antioxidants, Vol 12, Iss 12, p 2039 (2023)
Plant products, especially medicinal herbs and spices, have been used for centuries as a remedy to support human health and improve the flavor of food. Therefore, the purpose of this study was to identify plant species distinguished by their high con
Externí odkaz:
https://doaj.org/article/ff6fc1854b23451692a25a8903655a5c
Autor:
Marek Wesolowski, Edyta Leyk
Publikováno v:
Pharmaceutics, Vol 15, Iss 6, p 1596 (2023)
Reliable interpretation of the changes occurring in the samples during their heating is ensured by using more than one measurement technique. This is related to the necessity of eliminating the uncertainty resulting from the interpretation of data ob
Externí odkaz:
https://doaj.org/article/e586217681ca49b4aa2361e9b43c2351
Publikováno v:
Separations, Vol 10, Iss 5, p 277 (2023)
(1) Background: The concentration of amisulpride, an atypical antipsychotic drug, is most often determined in the blood, with many inconveniences. An alternative may be to use saliva as a diagnostic material for this purpose. The development of a met
Externí odkaz:
https://doaj.org/article/d755334aecae45148afaeee715f54b5e
Autor:
Ewelina Dziurkowska, Marek Wesolowski
Publikováno v:
Biomedicines, Vol 11, Iss 3, p 708 (2023)
The determination of antidepressant drugs and their metabolites in the body, mainly in the blood, allows for the monitoring of drug levels and their metabolism, helps identify drug interactions, and reduces the likelihood of increased side effects. D
Externí odkaz:
https://doaj.org/article/149958dda8ec47119e15b5e8eadaeb3c
Autor:
Anna Gumieniczek, Anna Berecka-Rycerz, Hanna Trębacz, Angelika Barzycka, Edyta Leyk, Marek Wesolowski
Publikováno v:
Molecules, Vol 27, Iss 13, p 4283 (2022)
Pharmaceutical excipients should not interact with active substances, however, in practice, they sometimes do it, affecting the efficacy, stability and safety of drugs. Thus, interactions between active substances and excipients are not desirable. Fo
Externí odkaz:
https://doaj.org/article/76820586c1de44448f6b85640fb0e107
Publikováno v:
Foods, Vol 11, Iss 5, p 667 (2022)
Background: Medicinal plants are often used in the treatment of diabetes mellitus, although knowledge about their mode of action and the substances responsible for their antidiabetic potential is limited. It is well known that some trace elements pla
Externí odkaz:
https://doaj.org/article/11caa0309fb942b59216477222dd1f28
Autor:
Edyta Leyk, Marek Wesolowski
Publikováno v:
Pharmaceutics, Vol 13, Iss 11, p 1836 (2021)
As amorphization may improve the solubility and bioavailability of a drug substance, the aim of this work was to assess to what extent the crystallinity of caffeine (CAF) and theophylline (TF) can be reduced by homogenization with a polymeric excipie
Externí odkaz:
https://doaj.org/article/e283acea960b40a68c5da3b18b9d866e
Autor:
Edyta Leyk, Marek Wesolowski
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Hydroxypropyl methylcellulose (hypromellose) is a widely known excipient commonly used in the preparation of drug formulations. It can interact with some active pharmaceutical ingredients (APIs), thereby contributing to a reduction in crystallinity,
Externí odkaz:
https://doaj.org/article/536171be75cc41eb9a3ac3a9870c955a
Autor:
Milena Polumackanycz, Mateusz Kaszuba, Agnieszka Konopacka, Urszula Marzec-Wróblewska, Marek Wesolowski, Krzysztof Waleron, Adam Buciński, Agnieszka Viapiana
Publikováno v:
Molecules, Vol 25, Iss 22, p 5272 (2020)
Rosa canina L. (dog rose) is a rich source of phenolic compounds that offer great hope for the prevention of chronic human diseases. Herein, wild and commercial samples of dog rose were chemically characterized with respect to their phenolic composit
Externí odkaz:
https://doaj.org/article/4985107b45b34bef871a4e55f807cc64
Publikováno v:
Pharmaceutics, Vol 12, Iss 7, p 648 (2020)
The low water solubility of benzodiazepines seriously affects their bioavailability and, in consequence, their biological activity. Since co-crystallization has been found to be a promising way to modify undesirable properties in active pharmaceutica
Externí odkaz:
https://doaj.org/article/e3e1ff08ad4148ec83e767c8e7d23086