Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Marek Vecera"'
Autor:
Michal Hendrych, Peter Solar, Marketa Hermanova, Ondrej Slaby, Hana Valekova, Marek Vecera, Alena Kopkova, Zdenek Mackerle, Tomas Kazda, Petr Pospisil, Radek Lakomy, Jan Chrastina, Jiri Sana, Radim Jancalek
Publikováno v:
Diagnostics, Vol 13, Iss 2, p 181 (2023)
Glioblastoma (GBM) is regarded as an aggressive brain tumor that rarely develops extracranial metastases. Despite well-investigated molecular alterations in GBM, there is a limited understanding of these associated with the metastatic potential. We h
Externí odkaz:
https://doaj.org/article/2d92de1fcac74c1f93785f454dc71447
Autor:
Michael Bartos, Frantisek Siegl, Alena Kopkova, Lenka Radova, Jan Oppelt, Marek Vecera, Tomas Kazda, Radim Jancalek, Michal Hendrych, Marketa Hermanova, Petra Kasparova, Zuzana Pleskacova, Vaclav Vybihal, Pavel Fadrus, Martin Smrcka, Radek Lakomy, Radim Lipina, Tomas Cesak, Ondrej Slaby, Jiri Sana
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Glioblastoma (GBM) is the most frequently occurring primary malignant brain tumor of astrocytic origin. To change poor prognosis, it is necessary to deeply understand the molecular mechanisms of gliomagenesis and identify new potential biomarkers and
Externí odkaz:
https://doaj.org/article/94d22527aabb4477a1afa411c71b7e62
Autor:
Jiri Sana, Petr Busek, Pavel Fadrus, Andrej Besse, Lenka Radova, Marek Vecera, Stefan Reguli, Lucie Stollinova Sromova, Marek Hilser, Radim Lipina, Radek Lakomy, Leos Kren, Martin Smrcka, Aleksi Sedo, Ondrej Slaby
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Abstract Glioblastoma stem-like cells (GSCs) are critical for the aggressiveness and progression of glioblastoma (GBM) and contribute to its resistance to adjuvant treatment. MicroRNAs (miRNAs) are small, non-coding RNAs controlling gene expression a
Externí odkaz:
https://doaj.org/article/45af015b41e7425cbe979cb802a41555
Autor:
Marek Vecera, Jiri Sana, Jan Oppelt, Boris Tichy, Kopkova Alena, Radim Lipina, Martin Smrcka, Radim Jancalek, Marketa Hermanova, Leos Kren, Ondrej Slaby
Publikováno v:
PLoS ONE, Vol 14, Iss 2, p e0211978 (2019)
Current progress in the field of next-generation transcriptome sequencing have contributed significantly to the study of various malignancies including glioblastoma multiforme (GBM). Differential sequencing of transcriptomes of patients and non-tumor
Externí odkaz:
https://doaj.org/article/569ca729b60648138682575f0af90093
Autor:
Alena Kopkova, Jiri Sana, Pavel Fadrus, Tana Machackova, Marek Vecera, Vaclav Vybihal, Jaroslav Juracek, Petra Vychytilova-Faltejskova, Martin Smrcka, Ondrej Slaby
Publikováno v:
PLoS ONE, Vol 13, Iss 12, p e0208580 (2018)
Associated with the pathogenesis of many cancers, including brain tumors, microRNAs (miRNAs) present promising diagnostic biomarkers. These molecules have been also studied in cerebrospinal fluid (CSF), showing great potential as a diagnostic tool in
Externí odkaz:
https://doaj.org/article/78ff707868664712af554f34af07d40c
Autor:
IVANA ROSKOVA, MAREK VECERA, LENKA RADOVA, KAROLINA TRACHTOVA, FRANTISEK SIEGL, MARKETA HERMANOVA, MICHAL HENDRYCH, LEOS KREN, VACLAV VYBIHAL, HANA VALEKOVA, PETRA KASPAROVA, IVANA KOLOUSKOVA, TOMAS KAZDA, ONDREJ SLABY, RADIM JANCALEK, JIRI SANA, MARTIN SMRCKA
Publikováno v:
Cancer Genomics Proteomics
CANCER GENOMICS & PROTEOMICS
CANCER GENOMICS & PROTEOMICS
Background/Aim: Brain metastases (BMs) are the most frequent intracranial tumors in adults and one of the greatest challenges for modern oncology. Most are derived from lung, breast, renal cell, and colorectal carcinomas and melanomas. Up to 14% of p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b37ec8f0990b3d6e18c0b700853e536
https://europepmc.org/articles/PMC9806667/
https://europepmc.org/articles/PMC9806667/
Autor:
Monika Vlachová, Lukáš Pečinka, Jana Gregorová, Lukáš Moráň, Tereza Růžičková, Petra Kovačovicová, Martina Almáši, Luděk Pour, Martin Štork, Roman Hájek, Tomáš Jelínek, Tereza Popková, Marek Večeřa, Josef Havel, Petr Vaňhara, Sabina Ševčíková
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Multiple myeloma (MM) is the second most prevalent hematological malignancy, characterized by infiltration of the bone marrow by malignant plasma cells. Extramedullary disease (EMD) represents a more aggressive condition involving the migrat
Externí odkaz:
https://doaj.org/article/123756e52c444a3ba9395eee02fa6b55
Autor:
Marek Vecera, Lenka Radova, Radim Lipina, Stefan Reguli, Martin Smrcka, Radim Jancalek, Michal Filip, Marketa Hermanova, Leos Kren, Dagmar Al Tukmachi, Tana Machackova, Petra Pokorna, Jiri Sana, Ondrej Slaby
Publikováno v:
Cancer Research. 83:3765-3765
Introduction: Glioblastoma (GBM) is the most frequent primary astrocytoma characterized by an aggressive and diffuse growth and a poor prognosis. The median survival of patients with GBM is only 12 to 16 months from diagnosis despite conventional the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71876566f59557c4792ae3eec7417b77
https://doi.org/10.1158/1538-7445.am2023-3765
https://doi.org/10.1158/1538-7445.am2023-3765
Autor:
Dagmar Al Tukmachi, Michaela Ruckova, Marek Vecera, Tana Machackova, Petra Pokorna, Marketa Hermanova, Michal Hendrych, Leos Kren, Ivana Roskova, Vaclav Vybihal, Hana Valekova, Radim Jancalek, Jiri Sana, Martin Smrcka, Ondrej Slaby
Publikováno v:
Cancer Research. 83:3758-3758
Brain metastases (BMs) comprise a heterogeneous group of the most frequent intracranial tumors in adults, most originating in lung, breast, renal cell, and colorectal carcinomas and melanomas. Despite the recent improvements in imaging methodology re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::918d99fbb47ffeefb2670800a8157e79
https://doi.org/10.1158/1538-7445.am2023-3758
https://doi.org/10.1158/1538-7445.am2023-3758
Autor:
Radim Jancalek, Marek Vecera, Frantisek Siegl, Jiri Sana, Karolina Trachtova, Michal Hendrych, Vaclav Vybihal, Martin Smrcka, Marketa Hermanova, Tomas Kazda, Ondrej Slaby
Publikováno v:
Neuro-Oncology. 24:vii149-vii150
BACKGROUND Brain metastases (BMs) are intracranial tumors that frequently occur in adult cancer patients. Because the prognosis of patients with BM individually varies, it would be useful to improve prognostic scoring tools by including new high-perf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::932e904dd72b81213384468ab05ba5c0
https://doi.org/10.1093/neuonc/noac209.575
https://doi.org/10.1093/neuonc/noac209.575