Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Marek Tchorzewski"'
Autor:
Adrian Zając, Aleksandra Maciejczyk, Joanna Sumorek-Wiadro, Kamil Filipek, Kamil Deryło, Ewa Langner, Jarosław Pawelec, Magdalena Wasiak, Mateusz Ścibiorski, Wojciech Rzeski, Marek Tchórzewski, Michał Reichert, Joanna Jakubowicz-Gil
Publikováno v:
Cells, Vol 12, Iss 23, p 2670 (2023)
Background: Gliomas are the most malignant tumors of the central nervous system. One of the factors in their high drug resistance is avoiding programmed death (PCD) induction. This is related to the overexpression of intracellular survival pathways:
Externí odkaz:
https://doaj.org/article/51b72680bbe74d72b50d4e4ce9271ad8
Autor:
Dawid Krokowski, Raul Jobava, Krzysztof J. Szkop, Chien-Wen Chen, Xu Fu, Sarah Venus, Bo-Jhih Guan, Jing Wu, Zhaofeng Gao, Wioleta Banaszuk, Marek Tchorzewski, Tingwei Mu, Phil Ropelewski, William C. Merrick, Yuanhui Mao, Aksoylu Inci Sevval, Helen Miranda, Shu-Bing Qian, Maria Manifava, Nicholas T. Ktistakis, Anastasios Vourekas, Eckhard Jankowsky, Ivan Topisirovic, Ola Larsson, Maria Hatzoglou
Publikováno v:
Cell reports. 40(3)
The integrated stress response (ISR) plays a pivotal role in adaptation of translation machinery to cellular stress. Here, we demonstrate an ISR-independent osmoadaptation mechanism involving reprogramming of translation via coordinated but independe
Fungal infections cause serious problems in many aspects of human life; especially infections by fungal species represent problems in immunocompromised patients. Current antifungal antibiotics target various metabolic pathways, predominantly the cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a245f663f029655c1d7b7b50cb9b2a23
https://doi.org/10.22541/au.162524119.91042257/v1
https://doi.org/10.22541/au.162524119.91042257/v1
Autor:
Mateusz Mołoń, Karolina Stępień, Patrycja Kielar, Bela Vasileva, Bonka Lozanska, Dessislava Staneva, Penyo Ivanov, Monika Kula-Maximenko, Eliza Molestak, Marek Tchórzewski, George Miloshev, Milena Georgieva
Publikováno v:
Cells, Vol 11, Iss 17, p 2754 (2022)
Ageing is accompanied by dramatic changes in chromatin structure organization and genome function. Two essential components of chromatin, the linker histone Hho1p and actin-related protein 4 (Arp4p), have been shown to physically interact in Saccharo
Externí odkaz:
https://doaj.org/article/5d077816eba94c979617fd4836672869
Autor:
Barbara Michalec-Wawiórka, Jakub Czapiński, Kamil Filipek, Patrycja Rulak, Arkadiusz Czerwonka, Marek Tchórzewski, Adolfo Rivero-Müller
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 10, p 5206 (2021)
Precise analysis of the genetic expression and functioning of proteins requires experimental approaches that, among others, enable tight control of gene expression at the transcriptional level. Doxycycline-induced Tet-On/Tet-Off expression systems pr
Externí odkaz:
https://doaj.org/article/e357692425d84548b5da60d2b76688f9
Autor:
Przemysław Grela, Xiao-Ping Li, Patrycja Horbowicz, Monika Dźwierzyńska, Marek Tchórzewski, Nilgun E. Tumer
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract The eukaryotic P-stalk contains two P1-P2 protein dimers with a conserved C- terminal domain (CTD) critical for the interaction with external factors. To understand the role of the individual CTD of human P1/P2 proteins, we examined the inte
Externí odkaz:
https://doaj.org/article/71d6133ab595498ea40a882565c22834
Autor:
Agnieszka Szuster-Ciesielska, Leszek Wawiórka, Dawid Krokowski, Nikodem Grankowski, Łukasz Jarosz, Urszula Lisiecka, Marek Tchórzewski
Publikováno v:
Journal of Immunology Research, Vol 2019 (2019)
Malaria remains one the most infectious and destructive protozoan diseases worldwide. Plasmodium falciparum, a protozoan parasite with a complex life cycle and high genetic variability responsible for the difficulties in vaccine development, is impli
Externí odkaz:
https://doaj.org/article/5d86bcb06cbb445897da16ef886f0b96
Publikováno v:
Cells, Vol 9, Iss 7, p 1745 (2020)
Aging is a biological phenomenon common to all living organisms. It is thought that the rate of aging is influenced by diverse factors, in many cases related to the control of energy metabolism, i.e., the so-called pro-longevity effects of starvation
Externí odkaz:
https://doaj.org/article/2db2c4ef41ed49c992926463c49e71cc
Publikováno v:
PLoS ONE, Vol 13, Iss 11, p e0207312 (2018)
Staphylococcus epidermidis small colony variants can survive inside macrophages and their survival has been proposed as a pivotal process in the pathogenesis of biomaterial associated infections. In the present study the intracellular location of cli
Externí odkaz:
https://doaj.org/article/12a912f7c3024df58e07c9cace8fe186
Autor:
Mostafa Fekry, Wessen Alshokry, Przemysław Grela, Marek Tchórzewski, Eva-Christina Ahlgren, Christopher A Söderberg, Oleksandr Gakh, Grazia Isaya, Salam Al-Karadaghi
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0184961 (2017)
Frataxin is a highly conserved protein found in both prokaryotes and eukaryotes. It is involved in several central functions in cells, which include iron delivery to biochemical processes, such as heme synthesis, assembly of iron-sulfur clusters (ISC
Externí odkaz:
https://doaj.org/article/276fdaea55a847fbbeb8f205105b7a57