Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Marek Strajbl"'
Autor:
Sharon Fischman, Itay Levin, Jean-Michel Rondeau, Marek Štrajbl, Sylvie Lehmann, Thomas Huber, Guy Nimrod, Régis Cebe, Dotan Omer, Jiri Kovarik, Shmuel Bernstein, Yehezkel Sasson, Alik Demishtein, Tomer Shlamkovich, Olga Bluvshtein, Noam Grossman, Reut Barak-Fuchs, Michael Zhenin, Yair Fastman, Shir Twito, Tal Vana, Nevet Zur, Yanay Ofran
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-13 (2023)
Abstract Antibody engineering technology is at the forefront of therapeutic antibody development. The primary goal for engineering a therapeutic antibody is the generation of an antibody with a desired specificity, affinity, function, and developabil
Externí odkaz:
https://doaj.org/article/1921facbf7654a2f948f646d19bc1cac
Autor:
Timothy Wyant, James Vasselli, Inbar Amit, Itay Levin, Natali Levitan, Reut Barak, May Ben-Mayor, Olga Bluvshtein, Noam Grossman, Yehezkel Sasson, Guy Nimrod, Michael Zehnin, Sharon Fischman, Marek Štrajbl, Liron Danielpur, Aron Knickerbocker, Yanay Ofran
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/6d4500839a8d4cf1870713fde2ba1876
Autor:
Guy Nimrod, Sharon Fischman, Mark Austin, Asael Herman, Feenagh Keyes, Olga Leiderman, David Hargreaves, Marek Strajbl, Jason Breed, Shelley Klompus, Kevin Minton, Jennifer Spooner, Andrew Buchanan, Tristan J. Vaughan, Yanay Ofran
Publikováno v:
Cell Reports, Vol 25, Iss 8, Pp 2121-2131.e5 (2018)
Summary: The ultimate goal of protein design is to introduce new biological activity. We propose a computational approach for designing functional antibodies by focusing on functional epitopes, integrating large-scale statistical analysis with multip
Externí odkaz:
https://doaj.org/article/e21b3c7b86a74d50adb9bf3461cc5156
Autor:
Natali Levitan, Yehezkel Sasson, Liron Danielpur, Tim Wyant, Inbar Amit, Marek Strajbl, Sharon Fischman, May Ben-Mayor, Itay Levin, Reut Barak, Aron Knickerbocker, Guy Nimrod, James Vasselli, Noam Grossman, Yanay Ofran, Olga Bluvshtein, Michael Zehnin
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
BackgroundIL-2 binds two forms of IL-2 receptor: a high affinity trimeric receptor composed of CD25, CD122, and CD132, and a low affinity dimeric receptor composed of CD122 and CD132. Binding to the dimeric receptors, expressed on effector cells, cau
Autor:
Marek Strajbl, Inbar Amit, Itay Levin, Guy Nimrod, Tim Wyant, Ruet Barak, Michael Zehnin, Olga Bluvshtein, Sharon Fischman, Yanay Ofran, Noam Grossman, Natali Levitan, Yehezkel Sasson
Publikováno v:
Journal of Clinical Oncology. 38:e15004-e15004
e15004 Background: Interleukin 2 is a 15.4 kDa type I cytokine of the four helix bundle structure. IL-2 signaling has two opposite effects, it can enhance immune response by activation of effector cells and regulate immune response by activation prol
Autor:
Jason Breed, Kevin Minton, Jennifer Spooner, Yanay Ofran, Feenagh Keyes, Tristan J. Vaughan, Sharon Fischman, Asael Herman, Guy Nimrod, Mark Austin, David J. Hargreaves, Olga Leiderman, Andrew Buchanan, Marek Strajbl, Shelley Klompus
Publikováno v:
Cell Reports, Vol 25, Iss 8, Pp 2121-2131.e5 (2018)
Summary: The ultimate goal of protein design is to introduce new biological activity. We propose a computational approach for designing functional antibodies by focusing on functional epitopes, integrating large-scale statistical analysis with multip
Publikováno v:
Methods in enzymology. 380