Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Marek Sawzdargo"'
Autor:
Brian F. O'Dowd, Susan R. George, Miles D. Thompson, Marek Sawzdargo, Michael Lamey, Hong Chi, George Varghese
Publikováno v:
Journal of Biological Chemistry. 277:9415-9421
We have shown in a previous study that desensitization and internalization of the human dopamine D1 receptor following short-term agonist exposure are mediated by temporally and biochemically distinct mechanisms. In the present study, we have used si
Autor:
Brian F. O'Dowd, Marek Sawzdargo, Henry H.Q. Heng, Tuan V. Nguyen, Dennis Lee, Regina Cheng, Susan R. George, Kevin R. Lynch
Publikováno v:
Molecular Brain Research. 64:193-198
The G protein-coupled receptor (GPCR) family share a structural motif of seven transmembrane segments with large numbers of conserved residues in those regions. Here, we report the identification and cloning of two novel human intronless GPCR genes,
Autor:
Thomas Nowak, Kevin R. Lynch, Brian F. O'Dowd, Henry H.Q. Heng, Adriano Marchese, Dong-Soon Im, Regina Cheng, Tuan V. Nguyen, Susan R. George, Marek Sawzdargo
Publikováno v:
Genomics. 56(1)
We have discovered three novel human genes, GPR34, GPR44, and GPR45, encoding family A G-protein-coupled receptors (GPCRs). The receptor encoded by GPR34 is most similar to the P2Y receptor subfamily, while the receptor encoded by GPR44 is most simil
Autor:
Lin-Lin Shiao, Brian F. O'Dowd, Anne Chateauneuf, Nathalie Coulombe, Tuan V. Nguyen, Michael P. Johnson, Suzanne R. Broussard, Gary P. O'Neill, Donna L. Hreniuk, Kathleen A. Sullivan, Gordon Y.K. Ng, Mark Abramovitz, Stacia Kargman, Roy G. Smith, Lee F. Kolakowski, Marek Sawzdargo, Habibeh Khoshbouei, Carina P. Tan, Andrew D. Howard, Susan R. George, Anita Tharian, Jilly F. Evans, Scott D. Feighner
Publikováno v:
Scopus-Elsevier
Galanin is a 29- or 30-amino acid peptide with wide-ranging effects on hormone release, feeding behavior, smooth muscle contractility, and somatosensory neuronal function. Three distinct galanin receptor (GALR) subtypes, designated GALR1, 2, and 3, h
Autor:
Lee F. Kolakowski, Shijie Xu, Marek Sawzdargo, Brian F. O'Dowd, Tuan V. Nguyen, Susan R. George
Publikováno v:
Biochemical and biophysical research communications. 239(2)
In our search for novel human galanin receptor (GALR) subtypes, human genomic DNA was PCR amplified using sets of degenerate primers based on conserved sequences in human and rat GALR. The sequence of one of the subcloned PCR products revealed homolo