Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Marek Sarissky"'
Publikováno v:
European Pharmaceutical Journal. 69:87-89
SAP and EAT-2 are intracellular adaptor proteins that link SLAMF receptors to downstream intracellular signalling pathways. Their expression and functions vary among different types of hematopoietic cells. The roles of SAP and EAT-2 in haematological
Publikováno v:
Leukemia & Lymphoma. 58:1726-1729
Chronic lymphocytic leukemia (CLL) is a neoplastic disorder characterized by the clonal expansion of malignant B cells which accumulate in the bone marrow and peripheral blood. CLL B cells are stro...
Publikováno v:
Molecular Biology Reports. 40:4129-4137
A novel series of naphthalimide polyamine conjugates were designed, synthesized and evaluated for in vitro antiproliferative activity against human leukemia (Jurkat), human cervical adenocarcinoma (HeLa), human breast adenocarcinoma (MCF-7) and human
Autor:
M Cizmarikova, Jan Mojzis, V Habalova, Mirossay A, Kohút A, L Schonova, M Wagnerova, Ladislav Mirossay, A Linkova, Marek Sarissky
Publikováno v:
The Pharmacogenomics Journal. 10:62-69
P-glycoprotein (PGP), the product of the MDR1 gene, is a transmembrane active efflux pump for a variety of carcinogens and cytostatics. It has been suggested that MDR1 polymorphisms contribute to the variability in cancer risk and therapeutic outcome
Publikováno v:
Surgical oncology. 24(3)
Treatment of benign meningiomas remains a challenge, especially when they involve the skull-base or when surgery and radiation fail. Moreover, a recent in vitro MTT (3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide) study testing hydr
Autor:
Pál Perjési, Jan Mojzis, David Drutovic, Martina Pilátová, Peter Kruzliak, Monica Lupi, Martina Chripkova, Giovanna Damia, Marek Sarissky, Massimo Broggini
Publikováno v:
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. 35(10)
Colorectal cancer is the third most common cancer in the world, with 1.2 million new cancer cases annually. Chalcones are secondary metabolite precursors of flavonoids that exhibit diverse biological activities, including antioxidant and antitumor ac
Autor:
Peter Kutschy, Lenka Varinská, Lenka Ivanova, Lydia Saxunova, Jan Mojzis, Ladislav Mirossay, Maria Repovska, Martina Pilátová, Marek Sarissky, Robert Seliga
Publikováno v:
Toxicology in vitro : an international journal published in association with BIBRA. 27(2)
The aim of the study was to investigate the cytotoxic activity of camalexin and its five synthetic derivatives in cancer and non-cancer cells. In cancer cells the benzocamalexin (BC) displayed the most potent activity with an IC50 value of 23.3–30.
Autor:
Ladislav Mirossay, Martina Pilátová, Marek Sarissky, Pál Perjési, Lenka Varinská, Peter Solár, Jan Mojzis, Alexander Ostro
Publikováno v:
Toxicology in vitro : an international journal published in association with BIBRA. 24(5)
As flavonoids, chalcones possess a wide variety of biological activities including anticancer properties. In the present study we have investigated the in vitro antiproliferative and antiangiogenic effects of four synthetic chalcones. E-2-(4′-metho
Publikováno v:
Bioelectrochemistry (Amsterdam, Netherlands). 56(1-2)
A number of structures with magnetic moments exists in living organisms that may be oriented by magnetic field. While most experimental efforts belong to the area of effects induced by weak and extremely low-frequency electromagnetic fields, we attem
Publikováno v:
Cellular & Molecular Neurobiology; Sep2009, Vol. 29 Issue 6/7, p845-858, 14p