Identification and validation of 174 COVID-19 vaccine candidate epitopes reveals low performance of common epitope prediction tools

Autor: Daniel Bisgaard Steen-Jensen, Marek Prachar, Ole Winther, Sune Justesen, Erik Jurgons, Stephan Thorgrimsen, Frederik Otzen Bagger

Publikováno v: Scientific Reports
Prachar, M, Justesen, S, Steen-Jensen, D B, Thorgrimsen, S, Jurgons, E, Winther, O & Bagger, F O 2020, ' Identification and validation of 174 COVID-19 vaccine candidate epitopes reveals low performance of common epitope prediction tools ', Scientific Reports, vol. 10, no. 1, 20465 . https://doi.org/10.1038/s41598-020-77466-4
Scientific Reports, Vol 10, Iss 1, Pp 1-8 (2020)
Prachar, M, Justesen, S, Steen-Jensen, D B, Thorgrimsen, S, Jurgons, E, Winther, O & Bagger, F O 2020, ' Identification and validation of 174 COVID-19 vaccine candidate epitopes reveals low performance of common epitope prediction tools ', Scientific Reports, vol. 10, 20465 . https://doi.org/10.1038/s41598-020-77466-4

The outbreak of SARS-CoV-2 (2019-nCoV) virus has highlighted the need for fast and efficacious vaccine development. Stimulation of a proper immune response that leads to protection is highly dependent on presentation of epitopes to circulating T-cell

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http://europepmc.org/articles/PMC7686376