Zobrazeno 1 - 10
of 119
pro vyhledávání: '"Marek Los"'
Autor:
Sabine Hombach‐Klonisch, Forouh Kalantari, Manoj Reddy Medapati, Suchitra Natarajan, Sai Nivedita Krishnan, Aditya Kumar‐Kanojia, Thatchawan Thanasupawat, Farhana Begum, Fred Y. Xu, Grant M. Hatch, Marek Los, Thomas Klonisch
Publikováno v:
Molecular Oncology, Vol 13, Iss 2, Pp 153-170 (2019)
Poly(ADP‐ribose) polymerase 1 inhibitors alone or in combination with DNA damaging agents are promising clinical drugs in the treatment of cancer. However, there is a need to understand the molecular mechanisms of resistance to PARP1 inhibitors. Ex
Externí odkaz:
https://doaj.org/article/6d09dbc596134a22a127ea18afe858e3
Autor:
Aleksandra Glogowska, Janette Pyka, Astrid Kehlen, Marek Los, Paul Perumal, Ekkehard Weber, Sheue-yann Cheng, Cuong Hoang-Vu, Thomas Klonisch
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 10, Iss 10, Pp 1120-1130 (2008)
The intracellular domains of the membrane-anchoring regions of some precursors of epidermal growth factor (EGF) family members have intrinsic biologic activities. We have determined the role of the human proEGF cytoplasmic domain (proEGFcyt) as part
Externí odkaz:
https://doaj.org/article/c8387519017a4d728911d762519397de
Autor:
Dipu Mohan Kumar, Mamoru Yamaguchi, Koshiro Miura, Mingqun Lin, Marek Los, Johannes F Coy, Yasuko Rikihisa
Publikováno v:
PLoS Pathogens, Vol 9, Iss 10, p e1003666 (2013)
Ehrlichia chaffeensis, an obligatory intracellular rickettsial pathogen, enters and replicates in monocytes/macrophages and several non-phagocytic cells. E. chaffeensis entry into mammalian cells is essential not only for causing the emerging zoonosi
Externí odkaz:
https://doaj.org/article/bcef2d8c932c465792e9221b21394514
Autor:
Soumya Panigrahi, Jörg Stetefeld, Jaganmohan R Jangamreddy, Soma Mandal, Sanat K Mandal, Marek Los
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e28395 (2012)
In this study we have calculated a 3D structure of apoptin and through modeling and docking approaches, we show its interaction with Bcr-Abl oncoprotein and its downstream signaling components, following which we confirm some of the newly-found inter
Externí odkaz:
https://doaj.org/article/656e78c4119b43bda0cc0181d4f7153a
Autor:
Saeid Ghavami, Mark M Mutawe, Pawan Sharma, Behzad Yeganeh, Karol D McNeill, Thomas Klonisch, Helmut Unruh, Hessam H Kashani, Dedmer Schaafsma, Marek Los, Andrew J Halayko
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e16523 (2011)
Statins inhibit the proximal steps of cholesterol biosynthesis, and are linked to health benefits in various conditions, including cancer and lung disease. We have previously investigated apoptotic pathways triggered by statins in airway mesenchymal
Externí odkaz:
https://doaj.org/article/355b8c38925742648fe47238996f5963
Autor:
Amir Barzegar Behrooz, Hamid Latifi-Navid, Akram Nezhadi, Maciej Świat, Marek Los, Zahra Jamalpoor, Saeid Ghavami
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1870:119482
Autor:
Abbas Afkhami, Shahla Shojaei, Mazaher Ahmadi, Marek Los, Parvaneh Mehrbod, Tayyebeh Madrakian, Hagar I. Labouta, Pooneh Mokarram, Dedmer Schaafsma, Nahid Rezvani Jalal, Michael Giersig, Saeid Ghavami
Publikováno v:
ACS Applied Nano Materials. 4:4307-4328
Magnetic nanomaterials (MNMs) have gained great interest from different fields of study ranging from wastewater treatment to (bio)sensor development, taking advantage of both nanoscale size (allowing high surface-to-volume ratios) and the opportunity
Autor:
Marveh Rahmati, Filip Machaj, Negar Azarpira, Mahmoud Aghaei, Philip Kawalec, Joseph W. Gordon, Marek Los, Ahmad Nasimian, Saeid Ghavami, David L. Perrin, S. Zahra Bathaie, Jakub Rosik, Afshin Samali, Bhavya Bhushan
Publikováno v:
Cancers, Vol 13, Iss 4927, p 4927 (2021)
Cancers; Volume 13; Issue 19; Pages: 4927
Cancers
Cancers; Volume 13; Issue 19; Pages: 4927
Cancers
Simple Summary The expression of BiP (GRP78), spliced XBP1 (sXBP1, nuclear XBP1), and IRE1α, were significantly associated with Rhabdomyosarcoma (RMS) in the four main RMS subtypes: alveolar (ARMS), embryonal (ERMS), pleomorphic (PRMS) and sclerosin
Autor:
Manoj Reddy Medapati, Thatchawan Thanasupawat, Fred Y. Xu, Farhana Begum, Thomas Klonisch, Grant M. Hatch, Marek Los, Aditya Kumar-Kanojia, Forouh Kalantari, Sabine Hombach-Klonisch, Suchitra Natarajan, Sai Nivedita Krishnan
Publikováno v:
Molecular Oncology
Molecular Oncology, Vol 13, Iss 2, Pp 153-170 (2019)
Molecular Oncology, Vol 13, Iss 2, Pp 153-170 (2019)
Poly(ADP‐ribose) polymerase 1 inhibitors alone or in combination with DNA damaging agents are promising clinical drugs in the treatment of cancer. However, there is a need to understand the molecular mechanisms of resistance to PARP1 inhibitors. Ex
Autor:
Sanaz Dastghaib, Kamran Bagheri Lankarani, Amir Ravandi, Nima Rezaei, Katarzyna Kotfis, Hagar I. Labouta, Naseer Ahmed, Ahmad Nasimian, Parvaneh Mehrbod, Shahla Shojaei, Marek Los, Tania Dehesh, Mohammadamin Sadeghdoust, Saeid Ghavami, Tayyebeh Madrakian, Farnaz Aligolighasemabadi, Pooneh Mokarram, Payam Peymani, Pooya Iranpour, Mazaher Ahmadi, Biniam Kidane, Pawan K. Sharma, Andrzej Madej
Publikováno v:
Translational Medicine Communications, Vol 6, Iss 1, Pp 1-14 (2021)
Translational Medicine Communications
Translational Medicine Communications
Background The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has profoundly affected the lives of millions of people. To date, there is no approved vaccine or specific dr